<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>This study was designed to determine the progressive pathological changes in the testis and epididymis of rabbit bucks experimentally infected with <italic>Trypanosoma brucei brucei</italic> (<italic>T. brucei</italic>). Fifteen local rabbit bucks were divided into 2 groups comprising 8 bucks in group A and 7 bucks in group B. Bucks in group A were infected intraperitoneally with approximately 1.0×10<sup>6</sup> of <italic>T. brucei</italic> while bucks in group B served as the uninfected control. The bucks were closely monitored for clinical signs of trypanosomosis from the time of infection till the end of the study. One buck from each group was humanely sacrificed on days 9, 19, 29 and 38 post-infection (pi) and its testis and epididymis were examined for pathological changes. At post mortem, no gross lesions were observed in the infected bucks except for adhesion of the testis and epididymis to the scrotum on days 29 and 38 pi. There were no histological changes in the testis and epididymis of the infected buck sacrificed on day 9 pi apart from mild depletion of the epididymal sperm reserve. The buck infected on day 19 pi had moderate testicular degeneration but the epididymis was devoid of sperm reserve. Severe testicular and epididymal degeneration was observed in the buck on days 29 and 38 pi. The testis and epididymis of bucks from the control group were normal with evidence of spermatogenic activities and full epididymal sperm reserve throughout. The study shows that infected bucks were unfit for breeding from day 19 pi.</p>
</abstract>

This study was designed to determine the progressive pathological changes in the testis and epididymis of rabbit bucks experimentally infected with Trypanosoma brucei brucei (T. brucei). Fifteen local rabbit bucks were divided into 2 groups comprising 8 bucks in group A and 7 bucks in group B. Bucks in group A were infected intraperitoneally with approximately 1.0×106 of T. brucei while bucks in group B served as the uninfected control. The bucks were closely monitored for clinical signs of trypanosomosis from the time of infection till the end of the study. One buck from each group was humanely sacrificed on days 9, 19, 29 and 38 post-infection (pi) and its testis and epididymis were examined for pathological changes. At post mortem, no gross lesions were observed in the infected bucks except for adhesion of the testis and epididymis to the scrotum on days 29 and 38 pi. There were no histological changes in the testis and epididymis of the infected buck sacrificed on day 9 pi apart from mild depletion of the epididymal sperm reserve. The buck infected on day 19 pi had moderate testicular degeneration but the epididymis was devoid of sperm reserve. Severe testicular and epididymal degeneration was observed in the buck on days 29 and 38 pi. The testis and epididymis of bucks from the control group were normal with evidence of spermatogenic activities and full epididymal sperm reserve throughout. The study shows that infected bucks were unfit for breeding from day 19 pi.

Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with <italic>Trypanosoma Brucei Brucei</italic>

Department of Theriogenology and Animal Production, Faculty of Veterinary Medicine

Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with 

This study was designed to determine the progressive pathological changes in the testis and epididymis of rabbit bucks experimentally infected with Trypanosoma...

Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with Trypanosoma Brucei Brucei

Published Online: Oct 26, 2021

Page range: 139 - 147

Received: Oct 23, 2020

Accepted: Mar 18, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0018

Keywords
epididymis, rabbit buck, sperm reserve, testis,

© 2021 Adewale Ayodeji Adeyeye et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with Trypanosoma Brucei Brucei

Published Online: Oct 26, 2021

Page range: 139 - 147

Received: Oct 23, 2020

Accepted: Mar 18, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0018

Keywordsepididymis, rabbit buck, sperm reserve, testis,

© 2021 Adewale Ayodeji Adeyeye et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
epididymis, rabbit buck, sperm reserve, testis,