<abstract xmlns="http://www.w3.org/1999/xhtml"><p>A one-day-old female Holstein calf was presented with subcutaneous masses spread over the whole body. Macroscopically, the masses were firm in touch, greyish-white in colour, 0.5-2 cm in diameter range. Histopathological examination confirmed the cutaneous Kaposiform hemangioendothelioma (KHE). Microscopic examination of the tumor revealed sheets of spindled endothelial cells forming vascular slits. Immunohistochemically, the tumor cells and capillaries gave strongly positive reaction for CD31 while vimentin, alpha smooth muscle actin and cytokeratin AE1/AE3 were negative. In this case, macroscopical, detailed histhopathological and immunohistochemical findings of congenital KHE reported firstly in a newborn calf.</p></abstract>

A one-day-old female Holstein calf was presented with subcutaneous masses spread over the whole body. Macroscopically, the masses were firm in touch, greyish-white in colour, 0.5-2 cm in diameter range. Histopathological examination confirmed the cutaneous Kaposiform hemangioendothelioma (KHE). Microscopic examination of the tumor revealed sheets of spindled endothelial cells forming vascular slits. Immunohistochemically, the tumor cells and capillaries gave strongly positive reaction for CD31 while vimentin, alpha smooth muscle actin and cytokeratin AE1/AE3 were negative. In this case, macroscopical, detailed histhopathological and immunohistochemical findings of congenital KHE reported firstly in a newborn calf.

Congenital Cutaneous Kaposiform Hemangioendothelioma in a Newborn Calf

Department of Pathology, Faculty of Veterinary Medicine

Department of Pathology, Faculty of Ceyhan Veterinary Medicine

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Congenital Cutaneous Kaposiform Hemangioendothelioma in a Newborn Calf"}

A one-day-old female Holstein calf was presented with subcutaneous masses spread over the whole body. Macroscopically, the masses were firm in touch,...

Congenital Cutaneous Kaposiform Hemangioendothelioma in a Newborn Calf

Published Online: Oct 15, 2020

Page range: 193 - 196

Received: Dec 23, 2019

Accepted: Mar 30, 2020

DOI: https://doi.org/10.2478/macvetrev-2020-0018

Keywords
kaposiform hemangioendothelioma, pathology, immunohistochemistry, new-born calf

© 2020 Erkmen Tuğrul Epikmen et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Congenital Cutaneous Kaposiform Hemangioendothelioma in a Newborn Calf

Published Online: Oct 15, 2020

Page range: 193 - 196

Received: Dec 23, 2019

Accepted: Mar 30, 2020

DOI: https://doi.org/10.2478/macvetrev-2020-0018

Keywordskaposiform hemangioendothelioma, pathology, immunohistochemistry, new-born calf

© 2020 Erkmen Tuğrul Epikmen et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
kaposiform hemangioendothelioma, pathology, immunohistochemistry, new-born calf