Effect of Curcuma longa maceration treatment on ovarian follicular development, serum oestradiol, uterine growth and vascularisation in female albino rats
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Fig. 1.
The uterine (A) and ovary (B) relative weight of experimental Sprague Dawley rats after 20 days’ treatment with Curcuma longa maceration at doses of 0% (Control), 1% (Cur-Low) or 5% (Cur-High). ANOVA – one-way analysis of variance; * – significant difference compared to the control group (P-value < 0.05); ns – non significant
Fig. 2.
Diameter (A), length (B), and vascularisation (C) of uterus in experimental Sprague Dawley rats after 20 days’ treatment with Curcuma longa maceration at doses of 0% (Control), 1% (Cur-Low) or 5% (Cur-High). ANOVA – one-way analysis of variance; NS/ns – non significant
Fig. 3.
Gross pathology of the uterus and its vascularisation in experimental Sprague Dawley rats after 20 days’ treatment with Curcuma longa maceration at doses of 0% (A – Control), 1% (B – Cur-Low) or 5% (C – Cur-High)
Fig. 4.
Histopathological visualisation showing the effect of 20 days’ Curcuma longa maceration administration on the uterine gland of experimental Sprague Dawley rats. The maceration was administered at doses of 0% (A – Control), 1% (B – Cur-Low) or 5% (C – Cur-High)
Fig. 5.
Histopathological visualisation showing the effect of 20 days’ Curcuma longa maceration administration on the follicles of experimental Sprague Dawley rats. The maceration was administered at doses of 0% (A – Control), 1% (B – Cur-Low) or 5% (C – Cur-High)
Fig. 6.
Immunohistochemical staining showing the effect of 20 days’ Curcuma longa maceration administration on the expression of ovarian vascular endothelial growth factor by experimental Sprague Dawley rats. The maceration was administered at doses of 0% (A – Control), 1% (B – Cur-Low) or 5% (C – Cur-High)
Fig. 7.
Serum follicle-stimulating hormone (FSH) (A), oestradiol (B) and progesterone (C) concentrations in experimental female Sprague Dawley rats after 20 days’ treatment with Curcuma longa maceration at doses of 0% (Control), 1% (Cur-Low) or 5% (Cur-High). ANOVA – one-way analysis of variance; * – significant difference compared to the control group (P-value < 0.05); ns – non significant