<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec>
<h3>Introduction</h3>
<p>The experiment was set to determine the effects of long-term (55-day) use of three commercial prebiotics including <italic>Saccharomyces cerevisiae</italic>–derived β-glucans and one including inulin on juvenile vimba <italic>(Vimba vimba)</italic> reared intensively under controlled conditions.</p>
</sec>
<sec>
<h3>Material and Methods</h3>
<p>Six-month-old fish were fed commercial feed (Control group, n = 90), or the same feed supplemented with 0.02% Leiber Beta-S (BS group, n = 90), 0.20% Biolex MB40 (MB group, n = 90), 0.30% CeFi (CE group, n = 90) or 1.00% inulin Orafti GR (IN group, n = 90) for 55 days.</p>
</sec>
<sec>
<h3>Results</h3>
<p>In the BS group, the final growth parameters were significantly lower than in the Control group, while the feed conversion ratio was significantly higher. No significant differences were found between any other group and the Control group in the respective parameters. The respiratory burst activity of the head-kidney phagocytes was significantly lower in all fish groups fed the prebiotic-supplemented diets compared to the Control group. The proliferative response of the head-kidney lymphocytes stimulated by concanavalin A was lower in the BS group than in the Control group, while in other groups this response was not affected. No significant differences were found in histopathological analyses of the digestive tract, liver or pancreas.</p>
</sec>
<sec>
<h3>Conclusion</h3>
<p>The long-term supplementation of fish diets with prebiotics can negatively influence the growth, feed conversion, nonspecific cellular resistance and proliferative activity of the T lymphocytes of vimba juveniles.</p>
</sec>
</abstract>

Introduction
The experiment was set to determine the effects of long-term (55-day) use of three commercial prebiotics including Saccharomyces cerevisiae–derived β-glucans and one including inulin on juvenile vimba (Vimba vimba) reared intensively under controlled conditions.


Material and Methods
Six-month-old fish were fed commercial feed (Control group, n = 90), or the same feed supplemented with 0.02% Leiber Beta-S (BS group, n = 90), 0.20% Biolex MB40 (MB group, n = 90), 0.30% CeFi (CE group, n = 90) or 1.00% inulin Orafti GR (IN group, n = 90) for 55 days.


Results
In the BS group, the final growth parameters were significantly lower than in the Control group, while the feed conversion ratio was significantly higher. No significant differences were found between any other group and the Control group in the respective parameters. The respiratory burst activity of the head-kidney phagocytes was significantly lower in all fish groups fed the prebiotic-supplemented diets compared to the Control group. The proliferative response of the head-kidney lymphocytes stimulated by concanavalin A was lower in the BS group than in the Control group, while in other groups this response was not affected. No significant differences were found in histopathological analyses of the digestive tract, liver or pancreas.


Conclusion
The long-term supplementation of fish diets with prebiotics can negatively influence the growth, feed conversion, nonspecific cellular resistance and proliferative activity of the T lymphocytes of vimba juveniles.

Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba <italic>(Vimba vimba)</italic>

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba 

Introduction
The experiment was set to determine the effects of long-term (55-day) use of three commercial prebiotics including Saccharomyces...

Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba (Vimba vimba)

Published Online: Jun 16, 2023

Page range: 233 - 241

Received: Jan 20, 2023

Accepted: May 22, 2023

DOI: https://doi.org/10.2478/jvetres-2023-0033

Keywords
innate immunity, aquaculture, β-glucan

© 2023 Barbara Kazuń et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba (Vimba vimba)

Published Online: Jun 16, 2023

Page range: 233 - 241

Received: Jan 20, 2023

Accepted: May 22, 2023

DOI: https://doi.org/10.2478/jvetres-2023-0033

Keywordsinnate immunity, aquaculture, β-glucan

© 2023 Barbara Kazuń et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
innate immunity, aquaculture, β-glucan