The impact of a modified anaesthetic protocol on animal survival and the characteristics of ventricular arrhythmias in the course of acute myocardial infarction in a domestic pig model

1Anand S.S., Islam S., Rosengren A., Franzosi M.G., Steyn K., Yusufali A.H., Keltai M., Diaz R., Rangarajan S., Yusuf S.: INTERHEART Investigators. Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. Eur Heart J 2008, 29, 932–940, doi: 10.1093/eurheartj/ ehn018. Anand S.S. Islam S. Rosengren A. Franzosi M.G. Steyn K. Yusufali A.H. Keltai M. Diaz R. Rangarajan S. Yusuf S. INTERHEART Investigators Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. Eur Heart J 2008 29 932 940 10.1093/eurheartj/ehn018Open DOISearch in Google Scholar

2Barkagan M., Leshem E., Rottmann M., Sroubek J., Shapira-Daniels A., Anter E.: Expandable lattice electrode ablation catheter. Circ Arrhythm Electrophysiol 2019, 12, e007090, doi: 10.1161/CIRCEP.118.007090. Barkagan M. Leshem E. Rottmann M. Sroubek J. Shapira-Daniels A. Anter E. Expandable lattice electrode ablation catheter Circ Arrhythm Electrophysiol 2019 12 e007090 10.1161/CIRCEP.118.007090Open DOISearch in Google Scholar

3Barrabés J.A., García-Dorado D., González M.A., Ruiz-Meana M., Solares J., Puigfel Y., Soler-Soler J.: Regional expansion during myocardial ischemia predicts ventricular fibrillation and coronary reocclusion. Am J Physiol 1998, 274, H1767–H1775, doi: 10.1152/ajpheart.1998.274.5.H1767. Barrabés J.A. García-Dorado D. González M.A. Ruiz-Meana M. Solares J. Puigfel Y. Soler-Soler J. Regional expansion during myocardial ischemia predicts ventricular fibrillation and coronary reocclusion Am J Physiol 1998 274 H1767 H1775 10.1152/ajpheart.1998.274.5.H1767Open DOISearch in Google Scholar

4Barrabés J.A., García-Dorado D., Padilla F., Agulló L., Trobo L., Carballo J., Soler-Soler J.: Ventricular fibrillation during acute coronary occlusion is related to the dilation of the ischemic region. Basic Res Cardiol 2002, 97, 445–451, doi: 10.1007/s003950200051. Barrabés J.A. García-Dorado D. Padilla F. Agulló L. Trobo L. Carballo J. Soler-Soler J. Ventricular fibrillation during acute coronary occlusion is related to the dilation of the ischemic region Basic Res Cardiol 2002 97 445 451 10.1007/s003950200051Open DOISearch in Google Scholar

5Berg R.A., Sanders A.B., Kern K.B., Hilwig R.W., Heidenreich J.W., Porter M.E., Ewy G.A.: Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest. Circulation 2001, 104, 2465–2470, doi: 10.1161/hc4501.098926. Berg R.A. Sanders A.B. Kern K.B. Hilwig R.W. Heidenreich J.W. Porter M.E. Ewy G.A. Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest Circulation 2001 104 2465 2470 10.1161/hc4501.098926Open DOISearch in Google Scholar

6Bergey J.L., Nocella K., McCallum J.D.: Acute coronary artery occlusion–reperfusion-induced arrhythmias in rats, dogs, and pigs: antiarrhythmic evaluation of quinidine, procainamide, and lidocaine. Eur J Pharmacol 1982, 81, 205–216, doi: 10.1016/0014-2999(82)90438-1. Bergey J.L. Nocella K. McCallum J.D. Acute coronary artery occlusion–reperfusion-induced arrhythmias in rats, dogs, and pigs: antiarrhythmic evaluation of quinidine, procainamide, and lidocaine Eur J Pharmacol 1982 81 205 216 10.1016/0014-2999(82)90438-1Open DOISearch in Google Scholar

7Bergey J.L., Wendt R.L., Nocella K., McCallum J.D.: Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol. Eur J Pharmacol 1984, 97, 95–103, doi: 10.1016/0014-2999(84)90516-8. Bergey J.L. Wendt R.L. Nocella K. McCallum J.D. Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol Eur J Pharmacol 1984 97 95 103 10.1016/0014-2999(84)90516-8Open DOISearch in Google Scholar

8Brener S.J., Witzenbichler B., Maehara A., Dizon J., Fahy M., El-Omar M., Dambrink J.-H., Genereux P., Mehran R., Oldroyd K., Parise H., Gibson C.M., Stone G.W.: Infarct size and mortality in patients with proximal versus mid left anterior descending artery occlusion: the Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction (INFUSE-AMI) trial. Am Heart J 2013, 166, 64–70, doi: 10.1016/j.ahj.2013.03.029. Brener S.J. Witzenbichler B. Maehara A. Dizon J. Fahy M. El-Omar M. Dambrink J.-H. Genereux P. Mehran R. Oldroyd K. Parise H. Gibson C.M. Stone G.W. Infarct size and mortality in patients with proximal versus mid left anterior descending artery occlusion: the Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction (INFUSE-AMI) trial Am Heart J 2013 166 64 70 10.1016/j.ahj.2013.03.029Open DOISearch in Google Scholar

9Chen Y., Shao D.-B., Zhang F.-X., Zhang J., Yuan W., Man Y.-L., Du W., Liu B.-X., Wang D.-W., Li X.-R., Cao K.-J.: Establishment and evaluation of a swine model of acute myocardial infarction and reperfusion-ventricular fibrillationcardiac arrest using the interventional technique. J Chin Med Assoc 2013, 76, 491–496, doi: 10.1016/j.jcma.2013.05.013. Chen Y. Shao D.-B. Zhang F.-X. Zhang J. Yuan W. Man Y.-L. Du W. Liu B.-X. Wang D.-W. Li X.-R. Cao K.-J. Establishment and evaluation of a swine model of acute myocardial infarction and reperfusion-ventricular fibrillationcardiac arrest using the interventional technique J Chin Med Assoc 2013 76 491 496 10.1016/j.jcma.2013.05.013Open DOISearch in Google Scholar

10Cherry B.H., Nguyen A.Q., Hollrah R.A., Olivencia-Yurvati A.H., Mallet R.T.: Modeling cardiac arrest and resuscitation in the domestic pig. World J Crit Care Med 2015, 4, 1–12, doi: 10.5492/wjccm.v4.i1.1. Cherry B.H. Nguyen A.Q. Hollrah R.A. Olivencia-Yurvati A.H. Mallet R.T. Modeling cardiac arrest and resuscitation in the domestic pig World J Crit Care Med 2015 4 1 12 10.5492/wjccm.v4.i1.1Open DOISearch in Google Scholar

11Clauss S., Bleyer C., Schüttler D., Tomsits P., Renner S., Klymiuk N., Wakili R., Massberg S., Wolf E., Kääb S.: Animal models of arrhythmia: classic electrophysiology to genetically modified large animals. Nat Rev Cardiol 2019, 16, 457–475, doi: 10.1038/s41569-019-0179-0. Clauss S. Bleyer C. Schüttler D. Tomsits P. Renner S. Klymiuk N. Wakili R. Massberg S. Wolf E. Kääb S. Animal models of arrhythmia: classic electrophysiology to genetically modified large animals Nat Rev Cardiol 2019 16 457 475 10.1038/s41569-019-0179-0Open DOISearch in Google Scholar

12Conradie S., Coetzee A., Coetzee J.: Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. Can J Anaesth 1999, 46, 71–81, doi:10.1007/bf03012519. Conradie S. Coetzee A. Coetzee J. Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane Can J Anaesth 1999 46 71–81 10.1007/bf03012519Open DOISearch in Google Scholar

13Crick S.J., Sheppard M.N., Ho S.Y., Gebstein L., Anderson R.H.: Anatomy of the pig heart: comparisons with normal human cardiac structure. J Anat 1998, 193, 105–119, 10.1046/j.1469-7580.1998.19310105.x Crick S.J. Sheppard M.N. Ho S.Y. Gebstein L. Anderson R.H. Anatomy of the pig heart: comparisons with normal human cardiac structure J Anat 1998 193 105 119 10.1046/j.1469-7580.1998.19310105.xSearch in Google Scholar

14Dib N., Diethrich E.B., Campbell A., Gahremanpour A., McGarry M., Opie S.R.: A percutaneous swine model of myocardial infarction. J Pharmacol Toxicol Methods 2006, 53, 256–263, doi: 10.1016/j.vascn.2005.10.005. Dib N. Diethrich E.B. Campbell A. Gahremanpour A. McGarry M. Opie S.R. A percutaneous swine model of myocardial infarction J Pharmacol Toxicol Methods 2006 53 256 263 10.1016/j.vascn.2005.10.005Open DOISearch in Google Scholar

15Di Diego J.M., Antzelevitch C.: Ischaemic ventricular arrhythmias: Experimental models and their clinical relevance. Heart Rhythm 2011, 8, 1963–1968, doi: 10.1016/j.hrthm.2011.06.036. Di Diego J.M. Antzelevitch C. Ischaemic ventricular arrhythmias: Experimental models and their clinical relevance Heart Rhythm 2011 8 1963 1968 10.1016/j.hrthm.2011.06.036Open DOISearch in Google Scholar

16Di Giosia P., Passacquale G., Petrarca M., Giorgini P., Marra A.M., Ferro A.: Gender differences in cardiovascular prophylaxis: focus on antiplatelet treatment. Pharmacol Res 2017, 119, 36–47, doi: 10.1016/j.phrs.2017.01.025. Di Giosia P. Passacquale G. Petrarca M. Giorgini P. Marra A.M. Ferro A. Gender differences in cardiovascular prophylaxis: focus on antiplatelet treatment Pharmacol Res 2017 119 36 47 10.1016/j.phrs.2017.01.025Open DOISearch in Google Scholar

17Eldar M., Ohad D., Bor A., Varda-Bloom N., Swanson D.K., Battler A.: A closed-chest pig model of sustained ventricular tachycardia. Pacing Clin Electrophysiol 1994, 17, 1603–1609, doi: 10.1111/j.1540-8159.1994.tb02353.x. Eldar M. Ohad D. Bor A. Varda-Bloom N. Swanson D.K. Battler A. A closed-chest pig model of sustained ventricular tachycardia Pacing Clin Electrophysiol 1994 17 1603 1609 10.1111/j.1540-8159.1994.tb02353.xOpen DOISearch in Google Scholar

18Elsman P., van ’t Hof A.W.J., Hoorntje J.C.A., de Boer M.-J., Borm G.F., Suryapranata H., Ottervanger J.P., Gosselink A.T.M., Dambrink J.-H.E., Zijlstra F.: Effect of coronary occlusion site on angiographic and clinical outcome in acute myocardial infarction patients treated with early coronary intervention. Am J Cardiol 2006, 97, 1137–1141, doi: 10.1016/j.amjcard.2005.11.027. Elsman P. van ’t Hof A.W.J. Hoorntje J.C.A. de Boer M.-J. Borm G.F. Suryapranata H. Ottervanger J.P. Gosselink A.T.M. Dambrink J.-H.E. Zijlstra F. Effect of coronary occlusion site on angiographic and clinical outcome in acute myocardial infarction patients treated with early coronary intervention Am J Cardiol 2006 97 1137 1141 10.1016/j.amjcard.2005.11.027Open DOISearch in Google Scholar

19Ewy G.A., Zuercher M., Hilwig R.W., Sanders A.B., Berg R.A., Otto Ch.W., Hayes M.M., Kern K.B.: Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest. Circulation 2007, 116, 2525–2530, doi: 10.1161/CIRCULATIONAHA.107.711820. Ewy G.A. Zuercher M. Hilwig R.W. Sanders A.B. Berg R.A. Otto Ch.W. Hayes M.M. Kern K.B. Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest Circulation 2007 116 2525–2530 10.1161/CIRCULATIONAHA.107.711820Open DOISearch in Google Scholar

20Garcia-Dorado D., Theroux P., Elizaga J., Galinanes M., Solares J., Riesgo M., Gomez M.J., Garcia-Dorado A., Fernandez Aviles F.: Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion. Cardiovasc Res 1987, 21, 537–544, doi: 10.1093/cvr/21.7.537. Garcia-Dorado D. Theroux P. Elizaga J. Galinanes M. Solares J. Riesgo M. Gomez M.J. Garcia-Dorado A. Fernandez Aviles F. Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion Cardiovasc Res 1987 21 537 544 10.1093/cvr/21.7.537Open DOISearch in Google Scholar

21Gavira J.J., Perez-Ilzarbe M., Abizanda G., Garcia-Rodriguez A., Orbe J., Paramo J.A., Belzunce M., Rabago G., Barba J., Herreros J., Panizo A., de Jalon J.A., Martinez-Caro D., Prosper F.: A comparison between percutaneous and surgical transplantation of autologous skeletal myoblasts in a swine model of chronic myocardial infarction. Cardiovasc Res 2006, 71, 744–753, doi: 10.1016/j.cardiores.2006.06.018. Gavira J.J. Perez-Ilzarbe M. Abizanda G. Garcia-Rodriguez A. Orbe J. Paramo J.A. Belzunce M. Rabago G. Barba J. Herreros J. Panizo A. de Jalon J.A. Martinez-Caro D. Prosper F. A comparison between percutaneous and surgical transplantation of autologous skeletal myoblasts in a swine model of chronic myocardial infarction Cardiovasc Res 2006 71 744 753 10.1016/j.cardiores.2006.06.018Open DOISearch in Google Scholar

22Gorenek B., Blomström Lundqvist C., Brugada Terradellas J., Camm A.J., Hindricks G., Huber K., Kirchhof P., Kuck K.-H., Kudaiberdieva G., Lin T., Raviele A., Santini M., Tilz R.R., Valgimigli M., Vos M.A., Vrints Ch., Zeymer U., Kristiansen S.B.: Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA and EAPCI task force. EuroIntervention 2015, 10, 1095–1108, doi: 10.4244/EIJY14M08_19. Gorenek B. Blomström Lundqvist C. Brugada Terradellas J. Camm A.J. Hindricks G. Huber K. Kirchhof P. Kuck K.-H. Kudaiberdieva G. Lin T. Raviele A. Santini M. Tilz R.R. Valgimigli M. Vos M.A. Vrints Ch. Zeymer U. Kristiansen S.B. Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA and EAPCI task force EuroIntervention 2015 10 1095 1108 10.4244/EIJY14M08_19Open DOISearch in Google Scholar

23Gourine A.V., Bulhak A., Gonon A.T., Pernow J., Sjoquist P.: Cardioprotective effect induced by brief exposure to nitric oxide before myocardial ischemia–reperfusion in vivo. Nitric Oxide 2002, 7, 210–216, doi: 10.1016/s1089-8603(02)00114-3. Gourine A.V. Bulhak A. Gonon A.T. Pernow J. Sjoquist P. Cardioprotective effect induced by brief exposure to nitric oxide before myocardial ischemia–reperfusion in vivo Nitric Oxide 2002 7 210 216 10.1016/s1089-8603(02)00114-3Open DOISearch in Google Scholar

24Hohmann S., Deisher A.J., Suzuki A., Konishi H., Rettmann M.E., Merrell K.W., Kruse J.J., Newman L.K., Parker K.D., Monahan K.H., Foote R.L., Herman M.G., Packer D.L.: Left ventricular function after noninvasive cardiac ablation using proton beam therapy in a porcine model. Heart Rhythm 2019, 16, 1710–1719, doi: 10.1016/j.hrthm.2019.04.030. Hohmann S. Deisher A.J. Suzuki A. Konishi H. Rettmann M.E. Merrell K.W. Kruse J.J. Newman L.K. Parker K.D. Monahan K.H. Foote R.L. Herman M.G. Packer D.L. Left ventricular function after noninvasive cardiac ablation using proton beam therapy in a porcine model Heart Rhythm 2019 16 1710 1719 10.1016/j.hrthm.2019.04.030Open DOISearch in Google Scholar

25Kren L., Meluzin J., Pavlovsky Z., Mayer J., Kala P., Groch L., Hornacek I., Rauser P., Vlasin M.: Experimental model of myocardial infarction: histopathology and reperfusion damage revisited. Pathol Res Pract 2010, 206, 647–650, doi: 10.1016/j.prp.2010.03.008. Kren L. Meluzin J. Pavlovsky Z. Mayer J. Kala P. Groch L. Hornacek I. Rauser P. Vlasin M. Experimental model of myocardial infarction: histopathology and reperfusion damage revisited Pathol Res Pract 2010 206 647 650 10.1016/j.prp.2010.03.008Open DOISearch in Google Scholar

26Krombach G.A., Kinzel S., Mahnken A.H., Günther R.W., Buecker A.: Minimally invasive closed-chest method for creating reperfused or occlusive myocardial infarction in swine. Invest Radiol 2005, 40, 14–18. Krombach G.A. Kinzel S. Mahnken A.H. Günther R.W. Buecker A. Minimally invasive closed-chest method for creating reperfused or occlusive myocardial infarction in swine Invest Radiol 2005 40 14 18Search in Google Scholar

27Leshem E., Zilberman I., Tschabrunn C.M., Barkagan M., Contreras-Valdes F.M., Govari A., Anter E.: High-Power and short-duration ablation for pulmonary vein isolation: biophysical characterization. JACC Clin Electrophysiol 2018, 4, 467–479, doi: 10.1016/j.jacep.2017.11.018. Leshem E. Zilberman I. Tschabrunn C.M. Barkagan M. Contreras-Valdes F.M. Govari A. Anter E. High-Power and short-duration ablation for pulmonary vein isolation: biophysical characterization JACC Clin Electrophysiol 2018 4 467 479 10.1016/j.jacep.2017.11.018Open DOISearch in Google Scholar

28Li X., Shao D., Wang G., Jiang T., Wu H., Gu B., Cao K., Zhang J., Qi L., Chen Y.: Effects of different LAD-blocked sites on the development of acute myocardial infarction and malignant arrhythmia in a swine model. J Thorac Dis 2014, 6, 1271–1277, doi: 10.3978/j.issn.2072-1439.2014.07.22. Li X. Shao D. Wang G. Jiang T. Wu H. Gu B. Cao K. Zhang J. Qi L. Chen Y. Effects of different LAD-blocked sites on the development of acute myocardial infarction and malignant arrhythmia in a swine model J Thorac Dis 2014 6 1271 1277 10.3978/j.issn.2072-1439.2014.07.22Open DOISearch in Google Scholar

29Li X.D., Yang Y.J., Geng Y.J., Zhao J.L., Zhang H.T., Cheng Y.T., Wu Y.L.: Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts: partially via the PKA signaling pathway. Acta Pharmacol Sin 2012, 33, 879–887, doi: 10.1038/aps.2012.27. Li X.D. Yang Y.J. Geng Y.J. Zhao J.L. Zhang H.T. Cheng Y.T. Wu Y.L. Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts: partially via the PKA signaling pathway Acta Pharmacol Sin 2012 33 879 887 10.1038/aps.2012.27Open DOISearch in Google Scholar

30Li Y., Ristagno G., Bisera J., Tang W., Deng O., Weil M.H.: Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. Crit Care Med 2008, 36, 211–215, doi: 10.1097/01.CCM.0000295594.93345.A2. Li Y. Ristagno G. Bisera J. Tang W. Deng O. Weil M.H. Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation Crit Care Med 2008 36 211 215 10.1097/01.CCM.0000295594.93345.A2Open DOISearch in Google Scholar

31Mader T.J., Kellogg A.R., Walterscheid J.K., Lodding C.C., Sherman L.D.: A randomized comparison of cardiocerebral and cardiopulmonary resuscitation using a swine model of prolonged ventricular fibrillation. Resuscitation 2010, 81, 596–602, doi: 10.1016/j.resuscitation.2010.01.013. Mader T.J. Kellogg A.R. Walterscheid J.K. Lodding C.C. Sherman L.D. A randomized comparison of cardiocerebral and cardiopulmonary resuscitation using a swine model of prolonged ventricular fibrillation Resuscitation 2010 81 596 602 10.1016/j.resuscitation.2010.01.013Open DOISearch in Google Scholar

32Manninger M., Zweiker D., van Hunnik A., Alogna A., Prassl A.J., Schipke J., Zeemering S., Zirngast B., Schönleitner P., Schwarzl M., Herbst V., Thon-Gutschi E., Huber S., Rohrer U., Ebner J., Brussee H., Pieske B.M., Heinzel F.R., Verheule S., Antoons G., Lueger A., Mühlfeld C., Plank G., Schotten U., Post H., Scherr D.: Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation. Heart Rhythm 2018, 15, 1328–1336, doi: 10.1016/j.hrthm.2018.05.016. Manninger M. Zweiker D. van Hunnik A. Alogna A. Prassl A.J. Schipke J. Zeemering S. Zirngast B. Schönleitner P. Schwarzl M. Herbst V. Thon-Gutschi E. Huber S. Rohrer U. Ebner J. Brussee H. Pieske B.M. Heinzel F.R. Verheule S. Antoons G. Lueger A. Mühlfeld C. Plank G. Schotten U. Post H. Scherr D. Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation Heart Rhythm 2018 15 1328 1336 10.1016/j.hrthm.2018.05.016Open DOISearch in Google Scholar

33Marchlinski F.E., Waxman H.L., Buxton A.E., Josephson M.E.: Sustained ventricular tachyarrhythmias during the early postinfarction period: electrophysiologic findings and prognosis for survival. J Am Coll Cardiol 1983, 2, 240–250, doi: 10.1016/s0735-1097(83)80159-4. Marchlinski F.E. Waxman H.L. Buxton A.E. Josephson M.E. Sustained ventricular tachyarrhythmias during the early postinfarction period: electrophysiologic findings and prognosis for survival J Am Coll Cardiol 1983 2 240 250 10.1016/s0735-1097(83)80159-4Open DOISearch in Google Scholar

34Millett E.R.C., Peters S.A.E., Woodward M.: Sex differences in risk factors for myocardial infarction: cohort study of UK Biobank participants. BMJ 2018, 363, k4247, doi: 10.1136/bmj.k4247. Millett E.R.C. Peters S.A.E. Woodward M. Sex differences in risk factors for myocardial infarction: cohort study of UK Biobank participants BMJ 2018 363 k4247 10.1136/bmj.k4247Open DOISearch in Google Scholar

35Munz M.R., Faria M.A., Monteiro J.R., Águas A.P., Amorim M.J.: Surgical Porcine Myocardial Infarction Model through Permanent Coronary Occlusion. Comp Med 2011, 61, 445–452. Munz M.R. Faria M.A. Monteiro J.R. Águas A.P. Amorim M.J. Surgical Porcine Myocardial Infarction Model through Permanent Coronary Occlusion Comp Med 2011 61 445 452Search in Google Scholar

36Naslund U., Haggmark S., Johansson G., Marklund L., Reiz S.: A closed-chest myocardial occlusion–reperfusion model in the pig: techniques, morbidity and mortality. Eur Heart J 1992, 13, 1282–1289, doi: 10.1093/oxfordjournals.eurheartj.a060350. Naslund U. Haggmark S. Johansson G. Marklund L. Reiz S. A closed-chest myocardial occlusion–reperfusion model in the pig: techniques, morbidity and mortality Eur Heart J 1992 13 1282 1289 10.1093/oxfordjournals.eurheartj.a060350Open DOISearch in Google Scholar

37Naslund U., Haggmark S., Johansson G., Pennert K., Reiz S., Marklund S.L.: Effects of reperfusion and superoxide dismutase on myocardial infarct size in a closed chest pig model. Cardiovasc Res 1992, 26, 170–178, doi: 10.1093/cvr/26.2.170. Naslund U. Haggmark S. Johansson G. Pennert K. Reiz S. Marklund S.L. Effects of reperfusion and superoxide dismutase on myocardial infarct size in a closed chest pig model Cardiovasc Res 1992 26 170 178 10.1093/cvr/26.2.170Open DOISearch in Google Scholar

38National Research Council (US) Committee for the Update of the Guide for the Care and Use of Laboratory Animals: Guide for the Care and Use of Laboratory Animals, 8th edition, National Academies Press (US), Washington (DC), 2011. National Research Council (US) Committee for the Update of the Guide for the Care and Use of Laboratory Animals Guide for the Care and Use of Laboratory Animals, 8th edition National Academies Press (US) Washington (DC) 2011Search in Google Scholar

39Niemann J.T., Rosborough J.P., Youngquist S.T., Shah A.P.: Transthoracic defibrillation potential gradients in a closed chest porcine model of prolonged spontaneous and electrically induced ventricular fibrillation. Resuscitation 2010, 81, 477–480, doi: 10.1016/j.resuscitation.2009.12.027. Niemann J.T. Rosborough J.P. Youngquist S.T. Shah A.P. Transthoracic defibrillation potential gradients in a closed chest porcine model of prolonged spontaneous and electrically induced ventricular fibrillation Resuscitation 2010 81 477 480 10.1016/j.resuscitation.2009.12.027Open DOISearch in Google Scholar

40Noszczyk-Nowak A., Cepiel A., Janiszewski A., Pasławski R., Gajek J., Pasławska U., Nicpoń J.: Normal values for heart electrophysiology parameters of healthy swine determined on electrophysiology study. Adv Clin Exp Med 2016, 25, 1249–1254, doi: 10.17219/acem/65808. Noszczyk-Nowak A. Cepiel A. Janiszewski A. Pasławski R. Gajek J. Pasławska U. Nicpoń J. Normal values for heart electrophysiology parameters of healthy swine determined on electrophysiology study Adv Clin Exp Med 2016 25 1249–1254 10.17219/acem/65808Open DOISearch in Google Scholar

41Odenstedt J., Mansson C., Jansson S.O., Grip L.: Endocardial electromechanical mapping in a porcine acute infarct and reperfusion model evaluating the extent of myocardial ischemia. J Invasive Cardiol 2003, 15, 497–501. Odenstedt J. Mansson C. Jansson S.O. Grip L. Endocardial electromechanical mapping in a porcine acute infarct and reperfusion model evaluating the extent of myocardial ischemia J Invasive Cardiol 2003 15 497 501Search in Google Scholar

42Parker G.W., Michael L.H., Hartley C.J., Skinner J.E., Entman M.L.: Central β-adrenergic mechanisms may modulate ischemic ventricular fibrillation in pigs. Circ Res 1990, 66, 259–270, doi: 10.1161/01.RES.66.2.259. Parker G.W. Michael L.H. Hartley C.J. Skinner J.E. Entman M.L. Central β-adrenergic mechanisms may modulate ischemic ventricular fibrillation in pigs Circ Res 1990 66 259–270 10.1161/01.RES.66.2.259Open DOISearch in Google Scholar

43Pasławska U., Noszczyk-Nowak A., Pasławski R., Janiszewski A., Kiczak L., Zyśko D., Nicpoń J., Jankowska E.A., Szuba A., Ponikowski P.: Normal electrocardiographic and echocardiographic (M-mode and two-dimensional) values in Polish Landrace pigs. Acta Vet Scand 2014, 56, 54–66, doi: 10.1186/s13028-014-0054-2. Pasławska U. Noszczyk-Nowak A. Pasławski R. Janiszewski A. Kiczak L. Zyśko D. Nicpoń J. Jankowska E.A. Szuba A. Ponikowski P. Normal electrocardiographic and echocardiographic (M-mode and two-dimensional) values in Polish Landrace pigs Acta Vet Scand 2014 56 54 66 10.1186/s13028-014-0054-2Open DOISearch in Google Scholar

44Perez de Prado A., Cuellas-Ramon C., Regueiro-Purrinos M., Gonzalo-Orden J.M., Perez-Martinez C., Altonaga J.R., GarciaIglesias M.J., Orden-Recio M.A., Garcia-Marin J.F., Fernandez-Vazquez F.: Closed-chest experimental porcine model of acute myocardial infarction-reperfusion. J Pharmacol Toxicol Methods 2009, 60, 301–306, doi: 10.1016/j.vascn.2009.05.007. Perez de Prado A. Cuellas-Ramon C. Regueiro-Purrinos M. Gonzalo-Orden J.M. Perez-Martinez C. Altonaga J.R. GarciaIglesias M.J. Orden-Recio M.A. Garcia-Marin J.F. Fernandez-Vazquez F. Closed-chest experimental porcine model of acute myocardial infarction-reperfusion J Pharmacol Toxicol Methods 2009 60 301 306 10.1016/j.vascn.2009.05.007Open DOISearch in Google Scholar

45Qin H., Walcott G.P., Killingsworth C.R., Rollins D.L., Smith W.M., Ideker R.E.: Impact of myocardial ischemia and reperfusion on ventricular defibrillation patterns, energy requirements, and detection of recovery. Circulation 2002, 105, 2537–2542, doi: 10.1161/01.cir.0000016702.86180.f6. Qin H. Walcott G.P. Killingsworth C.R. Rollins D.L. Smith W.M. Ideker R.E. Impact of myocardial ischemia and reperfusion on ventricular defibrillation patterns, energy requirements, and detection of recovery Circulation 2002 105 2537 2542 10.1161/01.cir.0000016702.86180.f6Open DOISearch in Google Scholar

46Reffelmann T., Sensebat O., Birnbaum Y., Stroemer E., Hanrath P., Uretsky B.F., Schwarz E.R.: A novel minimal-invasive model of chronic myocardial infarction in swine. Coron Artery Dis 2004, 15, 7–12, doi: 10.1097/00019501-20040200000002. Reffelmann T. Sensebat O. Birnbaum Y. Stroemer E. Hanrath P. Uretsky B.F. Schwarz E.R. A novel minimal-invasive model of chronic myocardial infarction in swine Coron Artery Dis 2004 15 7 12 10.1097/00019501-20040200000002Open DOISearch in Google Scholar

47Regueiro-Purriños M., Fernández-Vázquez F., Perez de Prado A., Altónaga J.R., Cuellas-Ramón C., Ajenjo-Silverio J.M., Orden A., Gonzalo-Orden J.M.: Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction. J Am Assoc Lab Anim Sci 2011, 50, 73–78. Regueiro-Purriños M. Fernández-Vázquez F. Perez de Prado A. Altónaga J.R. Cuellas-Ramón C. Ajenjo-Silverio J.M. Orden A. Gonzalo-Orden J.M. Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction J Am Assoc Lab Anim Sci 2011 50 73 78Search in Google Scholar

48Saeed M., Martin A.J., Saloner D., Do L., Wilson M.: Noninvasive MR characterization of structural and functional components of reperfused infarct. Acta Radiol 2010, 51, 1093–1102, doi: 10.3109/02841851.2010.520025. Saeed M. Martin A.J. Saloner D. Do L. Wilson M. Noninvasive MR characterization of structural and functional components of reperfused infarct Acta Radiol 2010 51 1093–1102 10.3109/02841851.2010.520025Open DOISearch in Google Scholar

49Savage R.M., Guth B., White F.C., Hagan A.D., Bloor C.M.: Correlation of regional myocardial blood flow and function with myocardial infarct size during acute myocardial ischemia in the conscious pig. Circulation 1981, 64, 699–707, doi: 10.1161/01.CIR.64.4.699. Savage R.M. Guth B. White F.C. Hagan A.D. Bloor C.M. Correlation of regional myocardial blood flow and function with myocardial infarct size during acute myocardial ischemia in the conscious pig Circulation 1981 64 699 707 10.1161/01.CIR.64.4.699Open DOISearch in Google Scholar

50Smart S.C., Sagar K.B., Warltier D.C.: Differential roles of Ca++ channels and Na+–Ca++ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion. Cardiovasc Res 1997, 36, 337–346, doi: 10.1016/s0008-6363(97)00187-9. Smart S.C. Sagar K.B. Warltier D.C. Differential roles of Ca++ channels and Na+–Ca++ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion Cardiovasc Res 1997 36 337 346 10.1016/s0008-6363(97)00187-9Open DOISearch in Google Scholar

51Sun S., Jiang Y., Zhen Z., Lai W.-H., Liao S., Tse H.-F.: Establishing a swine model of post-myocardial infarction heart failure for stem cell treatment. J Vis Exp 2020, 159, e60392, doi: 10.3791/60392. Sun S. Jiang Y. Zhen Z. Lai W.-H. Liao S. Tse H.-F. Establishing a swine model of post-myocardial infarction heart failure for stem cell treatment J Vis Exp 2020 159 e60392 10.3791/60392Open DOISearch in Google Scholar

52Suzuki Y., Lyons J.K., Yeung A.C., Ikeno F.: In vivo porcine model of reperfused myocardial infarction: in situ double staining to measure precise infarct area/area at risk. Catheter Cardiovasc Interv 2008, 71, 100–107, doi: 10.1002/ccd.21329. Suzuki Y. Lyons J.K. Yeung A.C. Ikeno F. In vivo porcine model of reperfused myocardial infarction: in situ double staining to measure precise infarct area/area at risk Catheter Cardiovasc Interv 2008 71 100 107 10.1002/ccd.21329Open DOISearch in Google Scholar

53Teunissen P.F.A., Horrevoets A.J.G., van Royen N.: The coronary collateral circulation: genetic and environmental determinants in experimental models and humans. J Mol Cell Cardiol 2012, 52, 897–904, doi: 10.1016/j.yjmcc.2011.09.010. Teunissen P.F.A. Horrevoets A.J.G. van Royen N. The coronary collateral circulation: genetic and environmental determinants in experimental models and humans J Mol Cell Cardiol 2012 52 897 904 10.1016/j.yjmcc.2011.09.010Open DOISearch in Google Scholar

54Thygesen K, Alpert J.S., Jaffe A.S., Chaitman B.R., Bax J.J, Morrow D.A., White H.D., The Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction: Fourth universal definition of myocardial infarction (2018). Circulation 2018, 138, e618–e651, doi: 10.1161/CIR.0000000000000617. Thygesen K Alpert J.S. Jaffe A.S. Chaitman B.R. Bax J.J Morrow D.A. White H.D. The Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction: Fourth universal definition of myocardial infarction (2018) Circulation 2018 138 e618 e651 10.1161/CIR.0000000000000617Open DOISearch in Google Scholar

55Tschabrunn C.M., Roujol S., Nezafat R., Faulkner-Jones B., Buxton A.E., Josephson M.E., Anter E.: A swine model of infarct-related reentrant ventricular tachycardia: Electroanatomic, magnetic resonance, and histopathological characterization. Heart Rhythm 2016, 13, 262–273, doi: 10.1016/j.hrthm.2015.07.030. Tschabrunn C.M. Roujol S. Nezafat R. Faulkner-Jones B. Buxton A.E. Josephson M.E. Anter E. A swine model of infarct-related reentrant ventricular tachycardia: Electroanatomic, magnetic resonance, and histopathological characterization Heart Rhythm 2016 13 262 273 10.1016/j.hrthm.2015.07.030Open DOISearch in Google Scholar

56Verdouw P.D., Remme W.J., Hugenholtz P.G.: Cardiovascular and antiarrhythmic effects of aprindine (AC 1802) during partial occlusion of a coronary artery in the pig. Cardiovasc Res 1977, 11, 317–325, doi: 10.1093/cvr/11.4.317. Verdouw P.D. Remme W.J. Hugenholtz P.G. Cardiovascular and antiarrhythmic effects of aprindine (AC 1802) during partial occlusion of a coronary artery in the pig Cardiovasc Res 1977 11 317 325 10.1093/cvr/11.4.317Open DOISearch in Google Scholar

57Vilahur G., Gutiérrez M., Casani L., Lambert C., Mendieta G., Ben-Aicha S., Capdevila A., Pons-Lladó G., Carreras F., Carlsson L., Hidalgo A., Badimon L.: P2Y12 antagonists and cardiac repair post-myocardial infarction: global and regional heart function analysis and molecular assessments in pigs. Cardiovasc Res 2018, 114, 1860–1870, doi: 10.1093/cvr/cvy201. Vilahur G. Gutiérrez M. Casani L. Lambert C. Mendieta G. Ben-Aicha S. Capdevila A. Pons-Lladó G. Carreras F. Carlsson L. Hidalgo A. Badimon L. P2Y12 antagonists and cardiac repair post-myocardial infarction: global and regional heart function analysis and molecular assessments in pigs Cardiovasc Res 2018 114 1860 1870 10.1093/cvr/cvy201Open DOISearch in Google Scholar

58Walcott G.P., Killingsworth C.R., Smith W.M., Ideker R.E.: Biphasic waveform external defibrillation thresholds for spontaneous ventricular fibrillation secondary to acute ischemia. J Am Coll Cardiol 2002, 39, 359–365, doi: 10.1016/s0735-1097(01)01723-5. Walcott G.P. Killingsworth C.R. Smith W.M. Ideker R.E. Biphasic waveform external defibrillation thresholds for spontaneous ventricular fibrillation secondary to acute ischemia J Am Coll Cardiol 2002 39 359 365 10.1016/s0735-1097(01)01723-5Open DOISearch in Google Scholar

59Walcott G.P., Kroll M.W., Ideker R.E.: Ventricular fibrillation: are swine a sensitive species? J Interv Card Electrophysiol 2015, 42, 83–89, doi: 10.1007/s10840-014-9964-1. Walcott G.P. Kroll M.W. Ideker R.E. Ventricular fibrillation: are swine a sensitive species? J Interv Card Electrophysiol 2015 42 83 89 10.1007/s10840-014-9964-1Open DOISearch in Google Scholar

60Wojakowski W., Tendera M., Cybulski W., Zuba-Surma E.K., Szade K., Florczyk U., Kozakowska M., Szymula A., Krzych L., Pasławska U., Pasławski R., Milewski K., Buszman P.P., Nabiałek E., Kuczmik W., Janiszewski A., Dzięgiel P., Buszman P.E., Józkowicz A., Dulak J.: Effects of intracoronary delivery of allogenic bone marrow-derived stem cells expressing heme oxygenase-1 on myocardial reperfusion injury. Thromb Haemost 2012, 108, 464–475, doi: 10.1160/TH12-05-0303. Wojakowski W. Tendera M. Cybulski W. Zuba-Surma E.K. Szade K. Florczyk U. Kozakowska M. Szymula A. Krzych L. Pasławska U. Pasławski R. Milewski K. Buszman P.P. Nabiałek E. Kuczmik W. Janiszewski A. Dzięgiel P. Buszman P.E. Józkowicz A. Dulak J. Effects of intracoronary delivery of allogenic bone marrow-derived stem cells expressing heme oxygenase-1 on myocardial reperfusion injury Thromb Haemost 2012 108 464 475 10.1160/TH12-05-0303Open DOISearch in Google Scholar

61Yang Y.-J., Zhao J.-L., You S.-J., Wu Y-J., Jing Z.-C., Yang W.-X., Meng L., Wang Y.-W., Gao R.-L.: Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion. Heart 2006, 92, 1131–1137, doi: 10.1136/hrt.2005.077164. Yang Y.-J. Zhao J.-L. You S.-J. Wu Y-J. Jing Z.-C. Yang W.-X. Meng L. Wang Y.-W. Gao R.-L. Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion Heart 2006 92 1131 1137 10.1136/hrt.2005.077164Open DOISearch in Google Scholar

62Zhao J.-L., Yang Y.-J., Wu Y.-J., Jing Z.-C., You S.-J., Yang W.-X., Meng L., Tian Y., Chen J.-L., Gao R.-L., Chen Z.-J.: Effects of anti-platelet drugs on myocardial no-reflow after acute myocardial infarction and reperfusion: experiment with mini-swine model. Zhonghua Yi Xue Za Zhi 2005, 85, 2187–2191, doi: 10.3760/j:issn:0376-2491.2005.31.008. Zhao J.-L. Yang Y.-J. Wu Y.-J. Jing Z.-C. You S.-J. Yang W.-X. Meng L. Tian Y. Chen J.-L. Gao R.-L. Chen Z.-J. Effects of anti-platelet drugs on myocardial no-reflow after acute myocardial infarction and reperfusion: experiment with mini-swine model Zhonghua Yi Xue Za Zhi 2005 85 2187 2191 10.3760/j:issn:0376-2491.2005.31.008Open DOISearch in Google Scholar