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Fatemeh G, Sajjad M, Niloufar R, Neda S, Leila S, Khadijeh M. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. J Neurol 2022 Jan; 269(1): 205–216. https://doi.org/10.1007/s00415-020-10381-w.Search in Google Scholar
Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Med Rev 2021 Dec; 60: 101556. https://doi.org/10.1016/j.smrv.2021.101556.Search in Google Scholar
Innocenti A, Lentini G, Rapacchietta S, Cinnirella P, Elia M, Ferri R, Bruni O. The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review. Int J Mol Sci 2023 Apr 25; 24(9): 7821. https://doi.org/10.3390/ijms24097821.Search in Google Scholar
Gardani M, Bradford DRR, Russell K, Allan S, Beattie L, Ellis JG, Akram U. A systematic review and meta-analysis of poor sleep, insomnia symptoms and stress in undergraduate students. Sleep Med Rev 2022 Feb; 61: 101565. https://doi.org/10.1016/j.smrv.2021.101565.Search in Google Scholar
Imafuku F, Yamamoto K, Tanaka E, Aoki R, Nishino S. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems. Nutrients 2023 May 19; 15(10): 2377. https://doi.org/10.3390/nu15102377.Search in Google Scholar
Chandra Shekhar H, Joshua L, Thomas J V. Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study. Adv Ther 2024 Jan; 41(1): 246–261. https://doi.org/10.1007/s12325-023-02708-6.Search in Google Scholar
Sahin K, Gencoglu H, Korkusuz AK, Orhan C, Aldatmaz İE, Erten F, Er B, Morde A, Padigaru M, Kilic E. Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Serotonin Receptor Activity in a Murine Model. Antioxidants (Basel) 2024 May 27; 13(6): 657. https://doi.org/10.3390/antiox13060657.Search in Google Scholar
Freund W, Weber F. The Function of Sleep and the Treatment of Primary Insomnia. Dtsch Arztebl Int 2023 Dec 15; 120: 863–870. https://doi.org/10.3238/arztebl.m2023.0228.Search in Google Scholar
Gutiérrez-Romero SA, Torres-Narváez ES, Zamora-Gómez AC, Castillo-Castillo S, Latorre-Velásquez AL, Betancourt-Villamizar C, Mendivil CO. Effect of a nutraceutical combination on sleep quality among people with impaired sleep: a randomised, placebo-controlled trial. Sci Rep 2024 Apr 5; 14(1): 8062. https://doi.org/10.1038/s41598-024-58661-z.Search in Google Scholar
Bhagavan C, Kung S, Doppen M, John M, Vakalalabure I, Oldfield K, Braithwaite I, Newton-Howes G. Cannabinoids in the Treatment of Insomnia Disorder: A Systematic Review and Meta-Analysis. CNS Drugs 2020 Dec; 34: 1217–1228. https://doi.org/10.1007/s40263-020-00773-x.Search in Google Scholar
Yeh WC, Chuang YC, Yen CW, Liu MC, Wu MN, Liou LM, Hsieh CF, Chien CF, Hsu CY. Static postural stability and neuropsychological performance after awakening from REM and NREM sleep in patients with chronic insomnia: a randomized, crossover, overnight polysomnography study. J Clin Sleep Med 2022 Aug 1; 18(8): 1983–1992. https://doi.org/10.5664/jcsm.10052.Search in Google Scholar
Shaha DP. Insomnia Management: A Review and Update. J Fam Pract 2023 Jul; 72(6 Suppl): S31–S36. https://doi.org/10.12788/jfp.0620.Search in Google Scholar
Wang WL, Chen KH, Pan YC, Yang SN, Chan YY. The effect of yoga on sleep quality and insomnia in women with sleep problems: a systematic review and meta-analysis. BMC Psychiatry 2020 May 1; 20(1): 195. https://doi.org/10.1186/s12888-020-02566-4.Search in Google Scholar
Gandolfi JV, Bernardo APA Di, Chanes DAV, Martin DF, Joles VB, Amendola CP, Sanches LU, Ciorlia GL, Lobo SM. The Effects of Melatonin Supplementation on Sleep Quality and Assessment of the Serum Melatonin in ICU Patients: A Randomized Controlled Trial. Crit Care Med 2020 Dec; 48(12): E1286–E1293. https://doi.org/10.1097/ccm.0000000000004690.Search in Google Scholar
Permuy M, López-Peña M, González-Cantalapiedra A, Muñoz F. Melatonin: A Review of Its Potential Functions and Effects on Dental Diseases. Int J Mol Sci 2017 Apr 19; 18(4): 865. https://doi.org/10.3390/ijms18040865.Search in Google Scholar
Xu H, Zhang C, Qian Y, Zou J, Li X, Liu Y, Zhu H, Meng L, Liu S, Zhang W, Yi H, Guan J, Chen Z, Yin S. Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial. Sleep Med 2020 Dec; 76: 113–119. https://doi.org/10.1016/j.sleep.2020.10.018.Search in Google Scholar
Pandit S, Srivastav AK, Sur TK, Chaudhuri S, Wang Y, Biswas TK. Effects of Withania somnifera Extract in Chronically Stressed Adults: A Randomized Controlled Trial. Nutrients 2024 Apr 26; 16(9): 1293. https://doi.org/10.3390/nu16091293.Search in Google Scholar
Cheah KL, Norhayati MN, Yaacob LH, Rahman RA. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One 2021 Sep 24; 16(9): e0257843. https://doi.org/10.1371/journal.pone.0257843.Search in Google Scholar
Deshpande A, Irani N, Balkrishnan R, Benny IR. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. Sleep Med 2020 Aug; 72: 28–36. https://doi.org/10.1016/j.sleep.2020.03.012.Search in Google Scholar
Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar D. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus 2019 Sep 28; 11(9): e5797. https://doi.org/10.7759/cureus.5797.Search in Google Scholar
Shinjyo N, Waddell G, Green J. Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis. J evidence-based Integr Med 2020 Jan-Dec; 25. https://doi.org/10.1177/2515690x20967323.Search in Google Scholar
Pachikian BD, Copine S, Suchareau M, Deldicque L. Effects of Saffron Extract on Sleep Quality: A Randomized Double-Blind Controlled Clinical Trial. Nutrients 2021 Apr 27; 13(5): 1473. https://doi.org/10.3390/nu13051473.Search in Google Scholar
Tajaddini A, Roshanravan N, Mobasseri M, Aeinehchi A, Sefid-Mooye Azar P, Hadi A, Ostadrahimi A. Saffron improves life and sleep quality, glycaemic status, lipid profile and liver function in diabetic patients: A double-blind, placebo-controlled, randomised clinical trial. Int J Clin Pract 2021 Aug; 75(8): e14334. https://doi.org/10.1111/ijcp.14334.Search in Google Scholar
Umigai N, Takeda R, Mori A. Effect of crocetin on quality of sleep: A randomized, double-blind, placebo-controlled, crossover study. Complement Ther Med 2018 Dec; 41: 47–51. https://doi.org/10.1016/j.ctim.2018.09.003.Search in Google Scholar
Milajerdi A, Jazayeri S, Shirzadi E, Hashemzadeh N, Azizgol A, Djazayery A, Esmaillzadeh A, Akhondzadeh S. The effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus: A double-blind, randomized and placebo-controlled clinical trial. Complement Ther Med 2018 Dec; 41: 196–202. https://doi.org/10.1016/j.ctim.2018.09.023.Search in Google Scholar
Kisiolek JN, Flores VA, Ramani A, Butler B, Haughian JM, Stewart LK. Eight Weeks of Daily Cannabidiol Supplementation Improves Sleep Quality and Immune Cell Cytotoxicity. Nutrients 2023 Sep 27; 15(19): 4173. https://doi.org/10.3390/nu15194173.Search in Google Scholar
Walsh JH, Maddison KJ, Rankin T, Murray K, McArdle N, Ree MJ, Hillman DR, Eastwood PR. Treating insomnia symptoms with medicinal cannabis: a randomized, crossover trial of the efficacy of a cannabinoid medicine compared with placebo. Sleep 2021 Nov 12; 44(11). https://doi.org/10.1093/sleep/zsab149.Search in Google Scholar
Ried K, Tamanna T, Matthews S, Sali A. Medicinal cannabis improves sleep in adults with insomnia: a randomised double-blind placebo-controlled crossover study. J Sleep Res 2023 Jun; 32(3). https://doi.org/10.1111/jsr.13793.Search in Google Scholar
Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, Kunugi H. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients 2019 Oct 3; 11(10): 2362. https://doi.org/10.3390/nu11102362.Search in Google Scholar
Sarris J, Byrne GJ, Cribb L, Oliver G, Murphy J, Macdonald P, Nazareth S, Karamacoska D, Galea S, Short A, Ee C, Birling Y, Menon R, Ng CH. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial. J Psychiatr Res 2019 Mar; 110: 31–37. https://doi.org/10.1016/j.jpsychires.2018.12.014.Search in Google Scholar
Baba Y, Inagaki S, Nakagawa S, Kaneko T, Kobayashi M, Takihara T. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study. J Med Food 2021 Apr; 24(4): 333–341. https://doi.org/10.1089/jmf.2020.4803.Search in Google Scholar
Moshfeghinia R, Sanaei E, Mostafavi S, Assadian K, Sanaei A, Ayano G. The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review. BMC Psychiatry 2024 Dec 4; 24(1): 886. A https://doi.org/10.1186/s12888-024-06285-y.Search in Google Scholar
Haybar H, Javid AZ, Haghighizadeh MH, Valizadeh E, Mohaghegh SM, Mohammadzadeh A. The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina. Clin Nutr ESPEN 2018 Aug; 26: 47–52. https://doi.org/10.1016/j.clnesp.2018.04.015.Search in Google Scholar
Safari M, Asadi A, Aryaeian N, Huseini HF, shidfar F, Jazayeri S, Malek M, Hosseini AF, Hamidi Z. The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial. BMC Complement Med Ther 2023 May 2; 23(1): 140. https://doi.org/10.1186/s12906-023-03978-x.Search in Google Scholar
Shirazi M, Jalalian MN, Abed M, Ghaemi M. The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial. Rev Bras Ginecol Obstet 2021 Feb; 43(2): 126–130. https://doi.org/10.1055/s-0040-1721857.Search in Google Scholar
Khaing W, Vallibhakara SAO, Tantrakul V, Vallibhakara O, Rattanasiri S, McEvoy M, Attia J, Thakkinstian. Calcium and Vitamin D Supplementation for Prevention of Preeclampsia: A Systematic Review and Network Meta-Analysis. Nutrients 2017 Oct 18; 9(10): 1141. https://doi.org/10.3390/nu9101141.Search in Google Scholar
Zhu C, Zhang Y, Wang T, Lin Y, Yu J, Xia Q, Zhu P, Zhu DM. Vitamin D supplementation improves anxiety but not depression symptoms in patients with vitamin D deficiency. Brain Behav 2020 Nov; 10(11): e01760. https://doi.org/10.1002/brb3.1760.Search in Google Scholar
Abboud M. Vitamin D Supplementation and Sleep: A Systematic Review and Meta-Analysis of Intervention Studies. Nutrients 2022 Mar 3; 14(5): 1076. https://doi.org/10.3390/nu14051076.Search in Google Scholar
Mirzaei-Azandaryani Z, Abdolalipour S, Mirghafourvand M. The effect of vitamin D on sleep quality: A systematic review and meta-analysis. Nutr Health 2022 Dec; 28(4): 515–526. https://doi.org/10.1177/02601060221082367.Search in Google Scholar
Majid MS, Ahmad HS, Bizhan H, Hosein HZM, Mohammad A. The effect of vitamin D supplement on the score and quality of sleep in 20–50 year-old people with sleep disorders compared with control group. Nutr Neurosci 2018 Sep; 21(7): 511–519. https://doi.org/10.1080/1028415x.2017.1317395.Search in Google Scholar
Gao Q, Kou T, Zhuang B, Ren Y, Dong X, Wang Q. The Association between Vitamin D Deficiency and Sleep Disorders: A Systematic Review and Meta-Analysis. Nutrients 2018 Oct 1; 10(10): 1395. https://doi.org/10.3390/nu10101395.Search in Google Scholar
Lee HJ, Hong JK, Kim JK, Kim DH, Jang SW, Han SW, Yoon IY. Effects of Probiotic NVP-1704 on Mental Health and Sleep in Healthy Adults: An 8-Week Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 2021 Jul 30; 13(8): 2660. https://doi.org/10.3390/nu13082660.Search in Google Scholar
Ho YT, Tsai YC, Kuo TBJ, Yang CCH. Effects of Lactobacillus plantarum PS128 on Depressive Symptoms and Sleep Quality in Self-Reported Insomniacs: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial. Nutrients 2021 Aug 17; 13(8): 2820. https://doi.org/10.3390/nu13082820.Search in Google Scholar
Harnett JE, Pyne DB, McKune AJ, Penm J, Pumpa KL. Probiotic supplementation elicits favourable changes in muscle soreness and sleep quality in rugby players. J Sci Med Sport 2021 Feb; 24(2): 195–199. https://doi.org/10.1016/j.jsams.2020.08.005.Search in Google Scholar
Fei Y, Wang R, Lu J, Peng S, Yang S, Wang Y, Zheng K, Li R, Lin L, Li M. Probiotic intervention benefits multiple neural behaviors in older adults with mild cognitive impairment. Geriatr Nurs 2023 May–Jun; 51: 167–175. https://doi.org/10.1016/j.gerinurse.2023.03.006.Search in Google Scholar
Lan Y, Lu J, Qiao G, Mao X, Zhao J, Wang G, Tian P, Chen W. Bifidobacterium breve CCFM1025 Improves Sleep Quality via Regulating the Activity of the HPA Axis: A Randomized Clinical Trial. Nutrients 2023 Nov 6; 15(21): 4700. https://doi.org/10.3390/nu15214700.Search in Google Scholar
Chu A, Samman S, Galland B, Foster M. Daily consumption of Lactobacillus gasseri CP2305 improves quality of sleep in adults – A systematic literature review and meta-analysis. Clin Nutr 2023 Aug; 42(8): 1314–1321. https://doi.org/10.1016/j.clnu.2023.06.019.Search in Google Scholar
Zhu R, Fang Y, Li H, Liu Y, Wei J, Zhang S, Wang L, Fan R, Wang L, Li S, Chen T. Psychobiotic Lactobacillus plantarum JYLP-326 relieves anxiety, depression, and insomnia symptoms in test anxious college via modulating the gut microbiota and its metabolism. Front Immunol 2023Mar 23; 14: 1158137. https://doi.org/10.3389/fimmu.2023.1158137.Search in Google Scholar
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