Clinical profile and outcome of children with haemophilia A: The Royal Hospital, Oman’s experience
Anood AlRawahi
Orcid profile, Ibrahim AlGaithi
Orcid profile, Fatma Al Riyami
Orcid profile, Maather Al Abri
Orcid profile, Hajer Al Shukaili
Orcid profile and Abdulhakim Al Rawahi
Orcid profile 
Article Category: Clinical Research
Published Online: Mar 19, 2025
Page range: 23 - 28
DOI: https://doi.org/10.2478/jhp-2025-0003
Keywords
© 2025 Anood AlRawahi et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Background
Data on clinical characteristics and bleeding outcome of Omani children with haemophilia A (HA) is limited. This study aims to describe the clinical profile and outcome of Omani children with HA at the Royal Hospital from 2006 to 2019.
Methods
This is a retrospective study including all Omani children (< 13 years) with HA at the Royal Hospital. Data included age at presentation, factor VIII (FVIII) level, treatment, complications, and bleeding episodes.
Results
Forty-four males were included; mean age was 1 year ± 1.7 years at presentation. Mean period of follow-up was 7.9 ± 3.6 years. The most common complaints at presentation were muscle bleeds (29.5%) and post-circumcision bleeding (11.4%). Two (4.5%) had mild HA, 29 (66%) had moderate HA, and 13 (29.5%) had severe HA. Twenty-eight (63.6%) were on regular prophylaxis, ten (22.7%) developed at least one target joint, and six (13.6%) developed FVIII inhibitors. The mean annualised bleeding rate was 1.8 ± 2.3, 4.6 ± 0.4, and 4.6 ± 8.6 for the persons with mild, moderate, and severe HA, respectively.
Conclusion
The clinical phenotype of Omani children is milder compared to other studies but with similar clinical outcomes.