<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jccm-2021-0034_s_006">
<h3>Introduction</h3>
<p>The current prescription and practice of net ultrafiltration among critically ill patients receiving kidney replacement therapy in the U.S. are unclear.</p></sec>
<sec id="j_jccm-2021-0034_s_007">
<h3>Aim of the study</h3>
<p>To assess the attitudes of U.S. critical care practitioners on net ultrafiltration (UF<sub>NET</sub>) prescription and practice among critically ill patients with acute kidney injury treated with kidney replacement therapy.</p></sec>
<sec id="j_jccm-2021-0034_s_008">
<h3>Methods</h3>
<p>A secondary analysis was conducted of a multinational survey of intensivists, nephrologists, advanced practice providers, and ICU and dialysis nurses practising in the U.S.</p></sec>
<sec id="j_jccm-2021-0034_s_009">
<h3>Results</h3>
<p>Of 1,569 respondents, 465 (29.6%) practitioners were from the U.S. Mainly were nurses and advanced practice providers (58%) and intensivists (38.2%). The median duration of practice was 8.7 (IQR, 4.2-19.4) years. Practitioners reported using continuous kidney replacement therapy (as the first modality in 60% (IQR 20%-90%) for UF<sub>NET</sub>. It was found that there was a significant variation in assessment of prescribed-to-delivered dose of UF<sub>NET</sub>, use of continuous kidney replacement therapy for UF<sub>NET</sub>, methods used to achieve UF<sub>NET</sub>, and assessment of net fluid balance during continuous kidney replacement therapy. There was also variation in interventions performed for managing hemodynamic instability, perceived barriers to UF<sub>NET</sub>, belief that early and protocol-based fluid removal is beneficial, and willingness to enroll patients in a clinical trial.</p></sec>
<sec id="j_jccm-2021-0034_s_010">
<h3>Conclusions</h3>
<p>There was considerable practice variation in UF<sub>NET</sub> among critical care practitioners in the U.S., reflecting the need to generate evidence-based practice guidelines for UF<sub>NET</sub>.</p></sec></abstract>

Introduction
The current prescription and practice of net ultrafiltration among critically ill patients receiving kidney replacement therapy in the U.S. are unclear.

Aim of the study
To assess the attitudes of U.S. critical care practitioners on net ultrafiltration (UFNET) prescription and practice among critically ill patients with acute kidney injury treated with kidney replacement therapy.

Methods
A secondary analysis was conducted of a multinational survey of intensivists, nephrologists, advanced practice providers, and ICU and dialysis nurses practising in the U.S.

Results
Of 1,569 respondents, 465 (29.6%) practitioners were from the U.S. Mainly were nurses and advanced practice providers (58%) and intensivists (38.2%). The median duration of practice was 8.7 (IQR, 4.2-19.4) years. Practitioners reported using continuous kidney replacement therapy (as the first modality in 60% (IQR 20%-90%) for UFNET. It was found that there was a significant variation in assessment of prescribed-to-delivered dose of UFNET, use of continuous kidney replacement therapy for UFNET, methods used to achieve UFNET, and assessment of net fluid balance during continuous kidney replacement therapy. There was also variation in interventions performed for managing hemodynamic instability, perceived barriers to UFNET, belief that early and protocol-based fluid removal is beneficial, and willingness to enroll patients in a clinical trial.

Conclusions
There was considerable practice variation in UFNET among critical care practitioners in the U.S., reflecting the need to generate evidence-based practice guidelines for UFNET.

Survey of U.S. Critical Care Practitioners on Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Kidney Replacement Therapy

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Introduction
The current prescription and practice of net ultrafiltration among critically ill patients receiving kidney replacement therapy in the U.S. are...

Survey of U.S. Critical Care Practitioners on Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Kidney Replacement Therapy

Article Category: Research article

Published Online: Nov 06, 2021

Page range: 272 - 282

Received: Mar 11, 2021

Accepted: Aug 24, 2021

DOI: https://doi.org/10.2478/jccm-2021-0034

Keywords
net ultrafiltration, critical care practitioners, renal replacement therapy, web-based survey

© 2021 Huiwen Chen, Raghavan Murugan, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Survey of U.S. Critical Care Practitioners on Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Kidney Replacement Therapy

Article Category: Research article

Published Online: Nov 06, 2021

Page range: 272 - 282

Received: Mar 11, 2021

Accepted: Aug 24, 2021

DOI: https://doi.org/10.2478/jccm-2021-0034

Keywordsnet ultrafiltration, critical care practitioners, renal replacement therapy, web-based survey

© 2021 Huiwen Chen, Raghavan Murugan, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
net ultrafiltration, critical care practitioners, renal replacement therapy, web-based survey