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Fig. 1

Ganzoni equation
Ganzoni equation

Fig. 2

Design of the study
Design of the study

Fig. 3

Haemoglobin levels variation between key moments
Haemoglobin levels variation between key moments

Fig. 4

Glucose influences increase in haemoglobin value
Glucose influences increase in haemoglobin value

Fig. 5

Quadratic analysis of haemoglobin trend variation
Quadratic analysis of haemoglobin trend variation

Bioumoral parameters for postoperative iron deficiency screening (mean (SD))

Parameters Values
Serum iron (μmol/L) 3.41 (1.67)
Transferrin saturation (%) 7.19 (2.74)
Ferritin (μg/L) 118.23 (17.22)
dTIBC (μmol/L) 48.80 (12.20)
MCV (fL) 85.46 (6.49)
MCH (g/dL) 28.34 (3.93)

Basic characteristics of included patients

Characteristics Values
Age in years. mean (SD ) 19-86. mean 58.90(19.06)

Gender (number) (%)
- female 8 (38.09)
- male 13 (61.90)

ASA* Score (number) (%)
- ASA II 4 (19.05)
- ASA III 14 (66.67)
- ASA IV 3 (14.28)

Type of surgery (number) (%)
- general surgery 7 (33.33)
- orthopaedics 9 (42.85)
- multiple trauma 5 (23.80)

Emergency vs elective (number) (%)
- emergency 11 (52.38)
- elective 10 (47.61)

Surgery duration in minutes; mean (SD)
- general surgery 172.85( 57.74)
- orthopaedics 155.62(41.18)
- multiple trauma 88 (41.66)

Intraoperative bleeding in mL; mean (SD)
- general surgery 745.71 (405.28)
- orthopaedics 653.7 (453.26)
- multiple trauma 610 (111.35)

Haemoglobin variation in g/dL (mean (SD)
- preoperative 11.78 (2.27)
- intraoperative 10.27 (1.81)
- pre-iron administration 8.51( 0.95)
- post-iron administration at 48 hours (I) 8.65 (0.91)
- post-iron administration at 72 hours (II) 8.84( 0.86)

Length of stay in hospital in days. 5 – 23 (mean = 10)

Postoperative bioumoral parameters measurements. Mean values(SD)

Parameter 48 hours after intervention 72 hours after intervention
Glycaemia (mg/dL) 125.5 (27.59) 124.8 (28.28)
Fibrinogen (mg/dL) 227.3 (34.07) 250.1 (25.15)
Urea (mg/dL) 31.95 (6.18) 29.86 (5.97)
Creatinine (mg/dL) 1.14 (0.30) 1.06 (0.22)
Lactate (mmol/L) 1.25 ( 0.48) 1.29 (0.34)
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