Effect of poloxamer 407 administration on the serum lipids profile, anxiety level and protease activity in the heart and liver of mice

Albert CM, Chae CU, Rexrode KM, Manson JE and Kawachi I. (2005). Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women. Circulation 111: 480-487.Search in Google Scholar

Baskin-Bey ES, Canbay A, Bronk SF, Werneburg N, Guicciardi ME, Nyberg SL and Gores GJ. (2005). Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury. Am J Physiol Gastrointest Liver Physiol 288: G396-402.Search in Google Scholar

Barrett A and Kirschke H. (1981). Cathepsin B, cathepsin H and cathepsin L. Meth Enzymol 80. Pt C: 535-561.Search in Google Scholar

Bellosta S and Bernini F. (2005) Modulation of macrophage function and metabolism. Hndb. Exp. Pharmacol. (HEP) 170: 665-695.Search in Google Scholar

Brix K, Dunkhorst A, Mayer K and Jordans S. Cysteine cathepsins: cellular roadmap to different functions. (2008) Biochimie 90: 194-207.10.1016/j.biochi.2007.07.02417825974Search in Google Scholar

Bromme D and Wilson S. (2011). Role of cysteine cathepsins in extracellular proteolysis. Extracellular Matrix Degradation. Biology of Extracellular Matrix, Vol. 2, 23-51.10.1007/978-3-642-16861-1_2Search in Google Scholar

Chow AK, Cena J and Schulz R. (2007). Acute actions and novel targets of matrix metallopro-teases in the heart and vasculature. Br J Pharmacol 152: 189-205.Search in Google Scholar

Cudic M and Fields GB. (2009). Extracellular proteases as targets for drug development. Curr Protein Pept Sci 10: 297-307.Search in Google Scholar

Cullen P, Rauterberg J and Lorkowski S. (2005). The pathogenesis of atherosclerosis. In: Handb. Exp. Pharmacol. (HEP) (Springer-Verlag,Berlin, Heidelberg), 170 Atherosclerosis, Diet and Drugs. Pt.1: 3-70.Search in Google Scholar

Derosa G, Maffioli P, D’Angelo A, Salvadeo SA, Ferrari I, Fogari E. et al. (2009). Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in combined dyslipidemia. Clin Invest Med 32: E124- E132.Search in Google Scholar

Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K and Watanabe S. (2011). Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression. Biochem BiophysRes Commun 412: 618-625.Search in Google Scholar

Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P and Weissleder R. (2008). Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation 118: 1802-1809.Search in Google Scholar

Ji G, Zhao X, Leng L, Liu P and Jiang Z. (2011). Comparison of dietary control and atorvastatin on high fat diet induced hepatic steatosis and hyperlipidemia in rats. Lipids Health Dis 10: 23.Search in Google Scholar

Johnston TP. (2004). The P-407-induced murine models of dose-controlled hyperlipidemia and atherosclerosis. J Cardiovasc Pharmacol 43: 595-606.Search in Google Scholar

Johnston TP. (2009). Poloxamer 407 increases soluble adhesion molecules, ICAM-1, VCAM-1, and E-selectin, in C57BL/6 mice. J Pharm Pharmacol 61: 1681-1688.Search in Google Scholar

Johnston TP. (2010). Poloxamer 407 as a general lipase inhibitor: its implications in lipid metabolism and atheroma formation in C57BL/6 mice. JPharm Pharmacol 62: 1807-1812.Search in Google Scholar

Johnston TP, Nguyen LB, Chu WA and Shefer S. (2001). Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis. Int J Pharm 229: 75-86.Search in Google Scholar

Kim DE, Kim JY, Schellingerhout D, Shon SM, Jeong SW, Kim EJ and Kim WK. (2009). Molecular imaging of cathepsin B proteolytic enzyme activity reflects the inflammatory component of atherosclerotic pathology and can quantitatively demonstrate the antiatherosclerotic therapeutic effects of atorvastatin and glucosamine. Mol Imaging 8: 291-301.Search in Google Scholar

Knight CG, Willenbrock F and Murphy G. (1992). A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases. FEBS Lett 296: 263-266.Search in Google Scholar

Korolenko TA, Cherkanova MS, Tuzikov FV, Johnston TP, Tuzikova NA, Loginova VM and Kaledin, VI. (2011). Influence of atorvastatin on fractional and subfractional composition of serum lipoproteins and MMP activity in mice with Triton WR 1339-induced lipemia. J Pharm Pharmacol 65: 833-839.Search in Google Scholar

Korolenko TA, Tuzikov FV, Cherkanova MS, Johnston TP, Tuzikova NA, Loginova VM, et al. (2012a). Influence of atorvastatin and carboxymethylated glucan on the serum lipoprotein profile and MMP activity of mice with poloxamer 407-induced lipemia. Can J Physiol Pharmacol 90: 141-153.10.1139/y11-11822320860Search in Google Scholar

Korolenko TA, Tuzikov FV, Johnston TP, Tuzikova NA, Kisarova YaA, Zhanaeva SYa et al. (2012b). The influence of repeated administration of poloxamer 407 on serum lipoproteins and protease activity in mouse liver and heart. Can J Physiol Pharmacol 90: 1456-1468.10.1139/y2012-11823181274Search in Google Scholar

Lowry OH, Rosebrough NJ, Farr AL and Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.Search in Google Scholar

Lutgens SP, Cleutjens KB, Daemen MJ and Heeneman S. Cathepsin cysteine proteases in cardiovascular disease. (2007). FASEB J 21: 3029-3041.10.1096/fj.06-7924com17522380Search in Google Scholar

Müller AL, Hryshko LV and Dhalla NS. (2012). Extracellular and intracellular proteases in cardiac dysfunction due to ischemia-reperfusion injury. Int JCardiol. Feb 2012.Search in Google Scholar

Ohira T, Diez Roux AV, Polak JF, Homma S, Iso H and Wasserman BA. (2012). Associations of anger, anxiety, and depressive symptoms with carotid arterial wall thickness: the multi-ethnic study of atherosclerosis. PsychosomMed 74: 517-525.Search in Google Scholar

Palmer WK, Emeson EE and Johnston TP. (1998). Poloxamer 407-induced atherogenesis in the C57BL/6 mouse. Atherosclerosis 136: 115-123.Search in Google Scholar

Peterson JT. (2006). The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors. Cardiovasc Res 69: 677-687.Search in Google Scholar

Qin Y and Shi GP. (2011). Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases. Pharmacol Ther131: 338-350.Search in Google Scholar

Reiser J, Adair B and Reinheckel T. (2010). Specialized roles for cysteine cathepsins in health and disease. J Clin Invest 120: 3421-34 31.Search in Google Scholar

Rodgers RJ and Dalvi A. (1997). Anxiety, defence and the elevated plus-maze. Neurosci Biobehav Rev 21: 801-810.Search in Google Scholar

Sjoberg S and Shi G-P. (2011). Cysteine protease cathepsins in atherosclerosis and abdominal aortic aneurysm. Clinic Rev Bone Miner Metab 9: 138-147.Search in Google Scholar

Sun M, Chen M, Liu Y, Fukuoka M, Zhou K, Li G. et al. (2011). Cathepsin-L contributes to cardiac repair and remodelling post-infarction. Circulation 89: 374-383.Search in Google Scholar

Tanaka H, Ishida T, Johnston TP, Yasuda T, Ueyama T, Kojima Y. et al. (2009). Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia. J Atheroscler Thromb 16: 327-338.Search in Google Scholar

Vasiljeva O, Reinheckel T, Peters C, Turk D, Turk, V and Turk, B. (2007). Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr Pharm Des 13 : 387-403.Search in Google Scholar

Warren A, Benseler V, Cogger VC, Bertolino P and Le Couteur DG. (2011). The impact of poloxamer 407 on the ultrastructure of the liver and evidence for clearance by extensive endothelial and Kupffer cell endocytosis. ToxicolPathol 39: 390-397.Search in Google Scholar

Wiederanders B, Kirschke H and Schaper S. (1986). The azocasein-urea-pepstatin assay discriminates between lysosomal proteinases. Biomed BiochimActa 45: 1477-1483.Search in Google Scholar