Resistance Exercise Machine within Lower Body Negative Pressure for Counteracting Effects of Microgravity

Baqai FP, Gridley DS, Slater JM, Luo-Owen X, Stodieck LS, Ferguson V, Chapes SK, Pecaut MJ (2009) Effects of spaceflight on innate immune function and antioxidant gene expression. Journal of Applied Physiology 106(6): 1935-1942 Baqai FP Gridley DS Slater JM Luo-Owen X Stodieck LS Ferguson V Chapes SK Pecaut MJ 2009 Effects of spaceflight on innate immune function and antioxidant gene expression Journal of Applied Physiology 106 6 1935 1942 Search in Google Scholar

Benson, A (2002) Motion sickness. In Medical Aspects of Harsh Environments textbooks of military medicine, K.B. Pandoff, R.E. Burr (eds), Washington, DC: Office of the Surgeon General, Department of the Army, Volume 2, pp 1049-1055 Benson A 2002 Motion sickness In Medical Aspects of Harsh Environments textbooks of military medicine Pandoff K.B. Burr R.E. Washington, DC Office of the Surgeon General, Department of the Army 2 1049 1055 Search in Google Scholar

Berg HE, Eiken O, Miklavcic L, Mekjavic IB (2007) Hip, thigh, and calf muscle atrophy and bone loss after 5-week bedrest inactivity. European Journal of Applied Physiology 99: 283-289 Berg HE Eiken O Miklavcic L Mekjavic IB 2007 Hip, thigh, and calf muscle atrophy and bone loss after 5-week bedrest inactivity European Journal of Applied Physiology 99 283 289 Search in Google Scholar

Boda WL, Watenpaugh DE, Ballard RE, Hargens AR (2000) Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise. Journal of Applied Physiology 89: 649-654 Boda WL Watenpaugh DE Ballard RE Hargens AR 2000 Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise Journal of Applied Physiology 89 649 654 Search in Google Scholar

Caillot-Augusseau A, Lafage-Proust M-H, Soler C, Pernod J, Dubois F, Alexandre C (1998) Bone formation and resorption biological markers in cosmonauts during and after a 180-day spaceflight (Euromir 95). Clinical Chemistry 44(3): 578-585 Caillot-Augusseau A Lafage-Proust M-H Soler C Pernod J Dubois F Alexandre C 1998 Bone formation and resorption biological markers in cosmonauts during and after a 180-day spaceflight (Euromir 95) Clinical Chemistry 44 3 578 585 Search in Google Scholar

Charles JB, Lathers CM (1991) Cardiovascular adaptation to spaceflight. Journal of Clinical Pharmacology 31(1): 1010–1023 Charles JB Lathers CM 1991 Cardiovascular adaptation to spaceflight Journal of Clinical Pharmacology 31 1 1010 1023 Search in Google Scholar

Convertino VA, Cooke WH (2005) Evaluation of cardiovascular risks of spaceflight does not support the NASA bioastronautics critical path roadmap. Aviation, Space, and Environmental Medicine 76: 869-876 Convertino VA Cooke WH 2005 Evaluation of cardiovascular risks of spaceflight does not support the NASA bioastronautics critical path roadmap Aviation, Space, and Environmental Medicine 76 869 876 Search in Google Scholar

Davis BL, Cavanaugh PR (1993) Simulating reduced gravity: a review of biomechanical issues pertaining to human motion. Aviation, Space, and Environmental Medicine 64(6): 557–566 Davis BL Cavanaugh PR 1993 Simulating reduced gravity: a review of biomechanical issues pertaining to human motion Aviation, Space, and Environmental Medicine 64 6 557 566 Search in Google Scholar

Dorfman TA, Levine BD, Tillery T, Peshock RM, Hastings JL, Schneider SM, Macias BR, Biolo G, Hargens AR (2007) Cardiac atrophy in women following bed rest. Journal of Applied Physiology 103: 8-16 Dorfman TA Levine BD Tillery T Peshock RM Hastings JL Schneider SM Macias BR Biolo G Hargens AR 2007 Cardiac atrophy in women following bed rest Journal of Applied Physiology 103 8 16 Search in Google Scholar

Gazenko OG, Gurovsky NN, Genin AM, Bryanov II, Eryomin AV, Egorov AD (1976) Results of medical investigations carried out on board the Salyut orbital stations. Life Science 14: 145–152 Gazenko OG Gurovsky NN Genin AM Bryanov II Eryomin AV Egorov AD 1976 Results of medical investigations carried out on board the Salyut orbital stations Life Science 14 145 152 Search in Google Scholar

Gianoudis J, Bailey CA, Sanders KM, Nowson CA, Hill K, Ebeling PR, Daly RM (2012) Osteo-cise: strong bones for life: protocol for a community-based randomised controlled trial of a multi-modal exercise and osteoporosis education program for older adults at risk of falls and fractures. BMC Musculoskeletal Disorders. 28:13: 78 Gianoudis J Bailey CA Sanders KM Nowson CA Hill K Ebeling PR Daly RM 2012 Osteo-cise: strong bones for life: protocol for a community-based randomised controlled trial of a multi-modal exercise and osteoporosis education program for older adults at risk of falls and fractures BMC Musculoskeletal Disorders 28 13 78 Search in Google Scholar

Hughson RL, Shoemaker JK, Blaber AP, Arbeille P, Greaves DK, Pereira-Junior PP, Xu D (2012) Cardiovascular regulation during long-duration spaceflights to the International Space Station. Journal of Applied Physiology 112: 719-727 Hughson RL Shoemaker JK Blaber AP Arbeille P Greaves DK Pereira-Junior PP Xu D 2012 Cardiovascular regulation during long-duration spaceflights to the International Space Station Journal of Applied Physiology 112 719 727 Search in Google Scholar

Lang T, LeBlanc A, Evans H, Lu Y, Genant H, Yu A (2004) Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight. Journal of Bone and Mineral Research 19: 1006-1012 Lang T LeBlanc A Evans H Lu Y Genant H Yu A 2004 Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight Journal of Bone and Mineral Research 19 1006 1012 Search in Google Scholar

Martinelli L, Russomano T, Santos M, Falcao F, Bauer M, Machado A, Sundaresan A (2009) Effect of microgravity on immune cell viability and proliferation simulation using 3-D clinostat. IEEE Engineering in Medicine and Biology Magazine 28(4): 85-90 Martinelli L Russomano T Santos M Falcao F Bauer M Machado A Sundaresan A 2009 Effect of microgravity on immune cell viability and proliferation simulation using 3-D clinostat IEEE Engineering in Medicine and Biology Magazine 28 4 85 90 Search in Google Scholar

Morgan JL, Zwart SR, Heer M, Ploutz-Snyder R, Ericson K, Smith SM (2012) Bone metabolism and nutritional status during 30-day head-down-tilt bed rest. Journal of Applied Physiology 113(10): 1519-1529 Morgan JL Zwart SR Heer M Ploutz-Snyder R Ericson K Smith SM 2012 Bone metabolism and nutritional status during 30-day head-down-tilt bed rest Journal of Applied Physiology 113 10 1519 1529 Search in Google Scholar

Mulavara AP, Feiveson AH, Fiedler J, Cohen H, Peters BT, Miller C, Brady R, Bloomberg JJ (2010) Locomotor function after long-duration spaceflight: effects and motor learning during recovery. Experimental Brain Research 202: 649-659 Mulavara AP Feiveson AH Fiedler J Cohen H Peters BT Miller C Brady R Bloomberg JJ 2010 Locomotor function after long-duration spaceflight: effects and motor learning during recovery Experimental Brain Research 202 649 659 Search in Google Scholar

NASA (2000) Anthropometric Source Book: Volume 1: Anthropometry for Designers Anthropology Staff/Webb Associates, NASA RP 1024, pp 7-78 NASA 2000 Anthropometric Source Book: Volume 1: Anthropometry for Designers Anthropology Staff/Webb Associates NASA RP 1024 7 78 Search in Google Scholar

Russomano T, Falcão F, Gurgel J, Piccoli L, Porto F, Dalmarco G, de Azevedo DFG, Allan J, Beck L, Petrat G, Thompsen S (2005) Development of a lower body negative pressure box with an environmental control system for physiological studies. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society 5: 4501-4504 Russomano T Falcão F Gurgel J Piccoli L Porto F Dalmarco G de Azevedo DFG Allan J Beck L Petrat G Thompsen S 2005 Development of a lower body negative pressure box with an environmental control system for physiological studies Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society 5 4501 4504 Search in Google Scholar

Schulz BW, Hart-Hughes S, Gordon MT, Bulat T (2012) Training implications of maximal forces on a computer-controlled and motor-driven leg press by age group, sex, footplate direction, and speed. Experimental Gerontology 47: 295-303 Schulz BW Hart-Hughes S Gordon MT Bulat T 2012 Training implications of maximal forces on a computer-controlled and motor-driven leg press by age group, sex, footplate direction, and speed Experimental Gerontology 47 295 303 Search in Google Scholar

Shackelford LC (2008) Musculoskeletal response to spaceflight, In Principles of Clinical Medicine for Spaceflight, M.R. Barratt, S.L. Pool (eds), pp 293-306. New York: Springer Shackelford LC 2008 Musculoskeletal response to spaceflight In Principles of Clinical Medicine for Spaceflight Barratt M.R. Pool S.L. 293 306 New York Springer Search in Google Scholar

Shackelford LC, LeBlanc AD, Driscoll TB, Evans HJ, Rianon NJ, Smith SM, Spector E, Feeback DL, Lai D (2004) Resistance exercise as a countermeasure to disuse-induced bone loss. Journal of Applied Physiology 97: 119-129 Shackelford LC LeBlanc AD Driscoll TB Evans HJ Rianon NJ Smith SM Spector E Feeback DL Lai D 2004 Resistance exercise as a countermeasure to disuse-induced bone loss Journal of Applied Physiology 97 119 129 Search in Google Scholar

Smith SM, Nillen JL, LeBlanc A, Lipton A, Demers LM, Lane HW, Leach CS (1998) Collagen cross-link excretion during spaceflight and bed rest. Journal of Clinical Endocrinology and Metabolism 83(10): 3584-3591 Smith SM Nillen JL LeBlanc A Lipton A Demers LM Lane HW Leach CS 1998 Collagen cross-link excretion during spaceflight and bed rest Journal of Clinical Endocrinology and Metabolism 83 10 3584 3591 Search in Google Scholar

Suh CH, Radcliffe CW (1978) Kinematics and Mechanisms Design, New York: Wiley Suh CH Radcliffe CW 1978 Kinematics and Mechanisms Design New York Wiley Search in Google Scholar

Thornton WE, Hoffler GW, Rummel JA (1977) Anthropometric changes and fluids shifts, In Biomedical Results from Skylab. RS Johnston, LF Dietlein, (eds.), pp 330-338. Washington, DC : Scientific and Technical Information Office, National Aeronautics and Space Administration. NASA SP-377 Thornton WE Hoffler GW Rummel JA 1977 Anthropometric changes and fluids shifts In Biomedical Results from Skylab Johnston RS Dietlein LF 330 338 Washington, DC Scientific and Technical Information Office, National Aeronautics and Space Administration NASA SP-377 Search in Google Scholar

Tidwell PH, Soper RR, Reinholtz CF (1996) Synthesis of Force-Generating Mechanisms, Proceedings of the 24th Biennial Mechanisms Conference, Irvine, California, August 18-22, paper 96-DETC/MECH-1211 Tidwell PH Soper RR Reinholtz CF 1996 Synthesis of Force-Generating Mechanisms Proceedings of the 24th Biennial Mechanisms Conference Irvine, California August 18-22 paper 96-DETC/MECH-1211 Search in Google Scholar

Trappe S, Costill D, Gallagher P, Creer A, Peters JR, Evans H, Riley D, Fitts R (2009) Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. Journal of Applied Physiology 106(4): 1159-1168 Trappe S Costill D Gallagher P Creer A Peters JR Evans H Riley D Fitts R 2009 Exercise in space: human skeletal muscle after 6 months aboard the International Space Station Journal of Applied Physiology 106 4 1159 1168 Search in Google Scholar

Vorobyev YI, Gazenko OG, Gurovskiy NN, Nefedov YG, Yegorov BB, Bayevskiy RM, Bryanov II, Genin AM, Degtyarev VA, Yegorov AD, Yeremin AV, Pestov ID (1976) Preliminary results of medical investigations carried out during flight of the second expedition of the Salyut-4 orbital station. Kosmicheskaya Biologiya I Aviakosmicheskaya Meditsina 10(5): 3-18 Vorobyev YI Gazenko OG Gurovskiy NN Nefedov YG Yegorov BB Bayevskiy RM Bryanov II Genin AM Degtyarev VA Yegorov AD Yeremin AV Pestov ID 1976 Preliminary results of medical investigations carried out during flight of the second expedition of the Salyut-4 orbital station Kosmicheskaya Biologiya I Aviakosmicheskaya Meditsina 10 5 3 18 Search in Google Scholar

Watenpaugh DE (2001) Fluid volume control during short-term spaceflight and implications for human performance. The Journal of Experimental Biology 204: 3209-3215 Watenpaugh DE 2001 Fluid volume control during short-term spaceflight and implications for human performance The Journal of Experimental Biology 204 3209 3215 Search in Google Scholar

Watenpaugh DE, Hargens AR (1996) The cardiovascular system in microgravity. In Handbook of Physiology: Environmental Physiology, Vol 1, Bethesda, MD: American Physiological Society, Sect 4, Vol 1, 29: 631-674 Watenpaugh DE Hargens AR 1996 The cardiovascular system in microgravity In Handbook of Physiology: Environmental Physiology 1 Bethesda, MD American Physiological Society Sect 4, Vol 1, 29 631 674 Search in Google Scholar

Zwart SR, Hargens AR, Lee SMC, Macias BR, Watenpaugh DE, Tse K, Smith SM (2007) Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins. Bone 40(2): 529–537 Zwart SR Hargens AR Lee SMC Macias BR Watenpaugh DE Tse K Smith SM 2007 Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins Bone 40 2 529 537 Search in Google Scholar