<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The <italic>in vitro</italic> activity of <italic>Cinnamomum cassia</italic>, <italic>Melaleuca alternifolia</italic>, and <italic>Cymbopogon citratus</italic> essential oils and antimycotics clotrimazole, fluconazole, and ketokonazole against <italic>T. mentagrophytes</italic> was evaluated by the disc-diffusion method. The essential oils were tested at 5, 10, 20, 30, 50, and 100 % concentration. It was found that <italic>Cymbopogon</italic>, commonly called lemongrass, and cinnamon show stable results independent of the concentration used, whereas the efficacy of tea tree oil, significantly decreases with the decreasing concentration. When comparing the efficacy of antimycotics the largest zone of inhibition was obtained with clotrimazole, while fluconazole proved to be ineffective. We found that cinnamon and lemongrass are more effective than the antimycotics that we have used. Our study confirmed that some essential oils can be used for the treatment of dermatophytoses caused by <italic>Trichophyton mentagrophytes</italic> and some of them are more effective than the commercial drugs.</p>
</abstract>

The in vitro activity of Cinnamomum cassia, Melaleuca alternifolia, and Cymbopogon citratus essential oils and antimycotics clotrimazole, fluconazole, and ketokonazole against T. mentagrophytes was evaluated by the disc-diffusion method. The essential oils were tested at 5, 10, 20, 30, 50, and 100 % concentration. It was found that Cymbopogon, commonly called lemongrass, and cinnamon show stable results independent of the concentration used, whereas the efficacy of tea tree oil, significantly decreases with the decreasing concentration. When comparing the efficacy of antimycotics the largest zone of inhibition was obtained with clotrimazole, while fluconazole proved to be ineffective. We found that cinnamon and lemongrass are more effective than the antimycotics that we have used. Our study confirmed that some essential oils can be used for the treatment of dermatophytoses caused by Trichophyton mentagrophytes and some of them are more effective than the commercial drugs.

<italic>In Vitro</italic> Antifungal Activity of Selected Essential Oils Against <italic>Trichophyton mentagrophytes</italic>

Department of Pharmacology and Toxicology

University of Veterinary Medicine and Pharmacy in Košice

Folia Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

 Antifungal Activity of Selected Essential Oils Against 

The in vitro activity of Cinnamomum cassia, Melaleuca alternifolia, and Cymbopogon citratus essential oils and antimycotics clotrimazole, fluconazole, and...

In Vitro Antifungal Activity of Selected Essential Oils Against Trichophyton mentagrophytes

Published Online: Jun 19, 2023

Page range: 33 - 41

Received: Apr 05, 2023

Accepted: May 15, 2023

DOI: https://doi.org/10.2478/fv-2023-0015

Keywords
antimycotics, Cinnamomi cassiae aetheroleum, Cymbopogon citratus aetheroleum, dermatophytoses, Melaleucae aetheroleum

© 2023 Lucia Kottferová et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

In Vitro Antifungal Activity of Selected Essential Oils Against Trichophyton mentagrophytes

Published Online: Jun 19, 2023

Page range: 33 - 41

Received: Apr 05, 2023

Accepted: May 15, 2023

DOI: https://doi.org/10.2478/fv-2023-0015

Keywordsantimycotics, Cinnamomi cassiae aetheroleum, Cymbopogon citratus aetheroleum, dermatophytoses, Melaleucae aetheroleum

© 2023 Lucia Kottferová et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
antimycotics, Cinnamomi cassiae aetheroleum, Cymbopogon citratus aetheroleum, dermatophytoses, Melaleucae aetheroleum