Open Access

The Role of Lymphatic Marker Prox-1 in Relation to Brain Tumours

 and    | Dec 30, 2021

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1. Absinta, M., Ha, S. K., Nair, G., Sati, P., Luciano, N. J., Palisoc, M., et al., 2017: Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI. eLife, 6., e29738.10.7554/eLife.29738562648228971799Search in Google Scholar

2. Adamczyk, L. A., Gordon, K., Kholová, I., Meijer-Lorna, L. B., Telinius, N., Gallager, P. J., et al., 2016: Lymph vessels: the forgotten second circulation in health in disease. Virchows Arch., 469, 1, 3—17. DOI: 10.1007/s00428-016-1945-6.10.1007/s00428-016-1945-6492311227173782Search in Google Scholar

3. Al-Kofahi, M., Yun Winny, J., Minagar, A., Alexander, S., 2017: Anatomy and roles of lymphatics in inflammatory diseases. Clin. Exper. Neuroimmunol., 8, 199—214.10.1111/cen3.12400Search in Google Scholar

4. Aspelund, A., Antila, S., Proulx, S. T., Karlsen, T. V., Karaman, S., Detmar, M., et al., 2015: A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J. Exp. Med., 212, 7, 991—999. DOI: 10.1084/jem.20142290.10.1084/jem.20142290449341826077718Search in Google Scholar

5. Bear, M. F., Connors, B. W., Paradiso, M. A., 2001: Neuroscience: Exploring the Brain. Baltimore, MD, Lippincott Williams and Wikins, 975 pp.Search in Google Scholar

6. Elsir, T., Eriksson, A., Orrego, A., Lindström, M. S., Nistér, M., 2010: Expression of PROX1 is a common feature of High-Grade malignant astrocytic gliomas. J. Neuropathol. Exp. Neurol., 69, 2, 129—138.10.1097/NEN.0b013e3181ca476720084020Search in Google Scholar

7. Elsir, T., Smits, A., Lindström, M. S., Nistér, M., 2012: Transcription factor PROX1: its role in development and cancer. Cancer Metastasis Rev., DOI: 10.1007/s10555-012-9390.10.1007/s10555-012-9390-8Search in Google Scholar

8. Farmanfarma Kalan, K. H., Mohammadian, M, Shahabinia, Z., Hassanipour, S., Salehiniya, H., 2019: Brain cancer in the world: An epidemiological review. World Cancer Res. J., 6, e1356. DOI: 10.32113/wcrj_20197_1356.Search in Google Scholar

9. Foubert, P., Varner, J. A., 2012: Integrins in tumour angiogenesis and lymphangiogenesis. Methods Mol. Biol., 757, 471—486. DOI: 10.1007/978-1-61779-166-6_27.10.1007/978-1-61779-166-6_27543362321909928Search in Google Scholar

10. Gale, N. W., Yancopoulos, N. D., 1999: Growth factors acting via endothelial cell-specific receptor tyrosin kinases: VEGFs, Angiopoietins and ephrins in vascular development. Genes. Dev., 13, 1055—1066. DOI: 10.1101/gad.13.9.1055.10.1101/gad.13.9.105510323857Search in Google Scholar

11. Gould, J., 2018: Breaking down brain cancer. Nature, 561, 40.10.1038/d41586-018-06704-730258156Search in Google Scholar

12. Hong, Y. K., Harvey, N., Noh, Y. H., Schacht, V., Hirakawa, S., Detmar, M., et al., 2002: Prox-1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev. Dyn., 225, 351—357. DOI: 10.1002/dvdy.10163.10.1002/dvdy.1016312412020Search in Google Scholar

13. Hu, X., Deng, Q., Ma, L., Li, Q., Chen, Y., Liao, Y., et al., 2020: Meningeal lymphatic vessels regulate brain tumour drainage and immunity. Cell Res., 30, 229—243. DOI: 10.1038/s41422-020-0287-8.10.1038/s41422-020-0287-8705440732094452Search in Google Scholar

14. Christiansen, A., Detmar, M., 2011: Lymphangiogenesis and cancer. Genes Cancer, 2, 12, 1146—1148. DOI: 10.1177/1947601911423028.10.1177/1947601911423028341112322866206Search in Google Scholar

15. Irschick, R., Siemon, C., Brenner, E., 2019: The history of anatomical research of lymphatics—from the ancient times to the end of the European renaissance. Ann. Anat., 223, 49—69. DOI: 10.1016/j.aanat.2019.01.010.10.1016/j.aanat.2019.01.01030731199Search in Google Scholar

16. Karpanen, T., Egeblad, M., Karkkainen, M. J., Kubo, H., Ylä-Herttuala, S., Jäättelä, M., et al., 2001: Vascular endothelial growth factor C promotes tumour lymphangiogenesis and intralymphatic tumour growth. Cancer Res., 61, 5, 1786—1790.Search in Google Scholar

17. Kong, L. L., Yang, N. Z., Shi, L. H., Zhao, G. H., Zhou, W., Ding, Q., et al., 2017: The optimum marker for the detection of lymphatic vessels. Mol. Clin. Res., 7, 515—520. DOI: 10. 3892/mco.2017.1356.10.3892/mco.2017.1356557420028855985Search in Google Scholar

18. Larjavaara, S., Mäntylä, R., Salminen, T., Haapasalo, H., Raitanen, J., Jääskeläinen, J., et al., 2007: Incidence of gliomas by anatomic location. Neuro-Oncology, 9, 3, 319—325. DOI: 10.1215/15228517-2007-016.10.1215/15228517-2007-016190742117522333Search in Google Scholar

19. Lavado, A., Oliver, G., 2007: Prox-1 expression patterns in the developing and adult murine brain. Dev. Dyn., 236, 518— 524. DOI: 10.1002/dvdy.21024.10.1002/dvdy.2102417117441Search in Google Scholar

20. Louveau, A., Herz, J., Nordheim Alme, M., Salvador, A. F., Dong, M. Q., Viar, K. E., et al., 2018: CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nat. Neurosci., 21, 10, 1380—1391. DOI: 10.1038/s41593-018-0227-9.10.1038/s41593-018-0227-9621461930224810Search in Google Scholar

21. Maloveská, M., Danko, J., Petrovová, E., Krešáková, L., Vdoviaková, K., Michalicová, A., et al., 2018: Dynamics of Evans blue clearance from cerebrospinal fluid into meningeal lymphatic vessels and deep cervical lymph nodes. Neurol. Res., 40, 5, 372—380. DOI: 10.1080/01616412.2018.1446282.10.1080/01616412.2018.144628229619904Search in Google Scholar

22. Meng, F. W., Liu, F. S., Liu, W. H., Li, L., Jie, L. L., 2020: Formation of new lymphatic vessels in glioma: An immunohistochemical analysis. Neuropathol., 40, 215—223. DOI: 10.1111/neup.12625.10.1111/neup.12625731719031960509Search in Google Scholar

23. Mesquita Da, S., Fu, Z., Kipnis, J., 2018: The meningeal lymphatic system: A new player in neurophysiology. Neuron, 100, 375—388. DOI: 10.1016/j.neuron.2018.09.022.10.1016/j.neuron.2018.09.022626816230359603Search in Google Scholar

24. Mezey, É., Szalayova, I., Hogden, Ch., Brady, A., Dósa, Á., Sótonyi, P., et al., 2021: An immunohistochemical study of lymphatic elements. PNAS, 118, 3, 1—12. DOI: 10.1073/pnas. 2002574118/.10.1073/pnasSearch in Google Scholar

25. Natale, G., Bocci, G., Ribatti, D., 2017: Scholars and scientists in the history of the lymphatic system. J. Anat., 231, 3, 417—429. DOI: 10.1111/joa.12644.10.1111/joa.12644Search in Google Scholar

26. Oliver, G., Sosa-Pineda, B., Geisendorf, S., Spana, E. P., Doe, Ch. Q., Gruss, P., 1993: Prox1, a prospero-related homeobox gene expressed during mouse development. Mech. Dev., 44, 1, 3—16. DOI: 10.1016/0925-4773(93)90012-M.10.1016/0925-4773(93)90012-MSearch in Google Scholar

27. Olszewski, W., 2003: The lymphatic systen in body homeostasis: Physiological conditions. Lymphat. Res. Biol., 1, 1, 11—21. DOI: 10.1089/15396850360495655.10.1089/15396850360495655Search in Google Scholar

28. Paduch, R., 2016: The role of lymphangiogenesis and angiogenesis in tumour metastasis. Cell Oncol., 39, 5, 397—410. DOI: 10.1007/s13402-016-0281-9.10.1007/s13402-016-0281-9Search in Google Scholar

29. Ray, L. A., Heys, J. J., 2019: Fluid flow and mass transport in brain tissue. Fluids, 4, 4, 1—30. DOI: 10.3390/fluids4040196.10.3390/fluids4040196Search in Google Scholar

30. Roodakker, K. R., Elsir, T., Edqvist, P. H. D., Hägerstrand, D., Carlson, J., Lysiak, M., et al., 2016: PROX-1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas results from independent glioblastoma cohorts stratified by age and IDH mutation status. Oncotarget, 7, 45, 72431—72442. DOI: 10.18632/oncotarget.11957.10.18632/oncotarget.11957Search in Google Scholar

31. Rudzinska, M., Ledwon, J. K., Gawel, D., Sikorska, J., Czarnocka, B., 2017: The role of prospero homeobox 1 (PROX1) expression in follicular thyroid carcinoma cells. Oncotarget, 8, 69, 114136—114155. DOI: 10.18632/oncotarget. 23167.10.18632/oncotargetSearch in Google Scholar

32. Skobe, M., Hamberg, L. M., Hawighorst, T., Schirner, M., Wolf, G. L., Alitalo, K., et al., 2001: Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma. Am. J. Pathol., 159, 3, 893—903. DOI: 10.1016/S0002-9440(10)61765-8.10.1016/S0002-9440(10)61765-8Search in Google Scholar

33. Sun, B. L., Wang, L. H., Yang, T., Sun, J. Y., Mao, L. L., Yang, M. F., et al., 2017: Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases. Prog. Neurobiol., 163–164, 118—143. DOI: 10.1016/j.pneurobio. 2017.08.007.10.1016/j.pneurobio.2017.08.007Search in Google Scholar

34. Suy, R., Thomis, S., Fourneau, I., 2016: The discovery of lymphatic system in the seventeenth century. Part I: The early history. Acta Chirurg. Belg., 116, 4, 260—266. DOI: 10.1080/000 15458.2016.1176792.10.1080/00015458.2016.1176792Search in Google Scholar

35. Tamura, R., Yoshida, K., Toda, M., 2019: Current understanding of lymphatic vessels in the central nervous system. Neurosurg. Rev., 43, 4, 1055—1064. DOI: 10.1007/s10143-019-01133-0.10.1007/s10143-019-01133-031209659Search in Google Scholar

36. Tomarev, S. I, Zinovieva, R. D., Chang, B., Hawes, N. L., 1998: Characterization of the mouse Prox-1 gene. Biochem. Biophys. Res. Commun., 248, 3, 684—689. DOI: 10.1006/bbrc. 1998.8989.10.1006/bbrc.1998.8989Search in Google Scholar

37. Veikkola, T., Jussila, L., Makinen, T., Karpanen, T., Jeltsch, M., Petrova, T. V., et al., 2001: Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J., 20, 6, 1223—1231. DOI: 10.1093/emboj/20.6.1223.10.1093/emboj/20.6.122314553211250889Search in Google Scholar

38. Witte, M. H., Jones, K., Wilting, J., Dictor, M., Selg, M., McHale, N., et al., 2006: Structure function relationships in the lymphatic system and implications for cancer biology. Cancer Metastasis Rev., 25, 2, 159—184. DOI: 10.1007/s10 555-006-8496-2.10.1007/s10555-006-8496-2Search in Google Scholar

39. Xu, X., Wan, X., Wei, X., 2017: PROX-1 promotes human glioblastoma cell proliferation and invasion via activation of the nuclear factor-κB signaling pathway. Mol. Med. Rep., 15, 963—968. DOI: 10.3892/mmr.2016.6075.10.3892/mmr.2016.607528035380Search in Google Scholar

40. Zinovieva, R. D., Duncan, M. K., Johnson, T. R., Torres, R., Polymeropoulos, M. H., Tomarev, S. I., 1996: Structure and chromosomal localization of the human homeobox gene Prox-1. Genomics, 35, 517—522.10.1006/geno.1996.03928812486Search in Google Scholar

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