The Difference in the Mucus Organization Between the Small and Large Intestine and Its Protection of Selected Natural Substances. A Review

1. Abiodun, O. O., Rodriguez-Nogales, A., Algieri, F., Gomez-Caravaca, A. M., Segura-Carretero, A., Utrilla, M. P., et al., 2016: Antiinflamatory and immunomodulatory activity of an ethanolic extract from the stem bark of Terminalia catappa L. (Combretaceae): in vitro and in vivo evidences. Journal of Ethnopharmacology, 192, 309—319.10.1016/j.jep.2016.07.056Search in Google Scholar

2. Aliakbarpour, H. R., Chamani, M., Rahimi, G., Sadeghi, A. A., Qujeq, D., 2012: The Bacillus subtilis and lactic acid bacteria probiotics influence intestinal mucin gene expression, histomorphology and growth performance in broilers. Asian-Australas. J. Anim. Sci., 25, 1285—1293.10.5713/ajas.2012.12110Search in Google Scholar

3. Bäckström, M., Ambort, D., Thomsson, E., Johansson, M. E., Hansson, G. C., 2013: Increased understanding of the biochemistry and biosynthesis of MUC2 and other gel-forming mucins through the recombinant expression of their protein domains. Mol. Biotechnol., 54, 250—256.10.1007/s12033-012-9562-3Search in Google Scholar

4. Bermudez-Brito, M., Plaza-Díaz, J., Muñoz-Quezada, S., Gómez-Llorente, C., Gil A., 2012: Probiotic Mechanisms of Action. Ann. Nutr. Metab., 61, 160—174.10.1159/000342079Search in Google Scholar

5. Blaschek, H. P., Wang, H. H., Agle, M. E., 2007:Biofilms in the Food Environment, 1st edn., IFT Press, Blackwell Publishing Iowa, USA, 193 pp.10.1002/9780470277782Search in Google Scholar

6. Birchenough, G. M. H., Johansson, M. E. V., Gustafsson, J. K., Bergström, J. H., Hansson, G. C., 2015: New developments in goblet cell mucus secretion and function. Mucosal Immunol., 8, 712—719.10.1038/mi.2015.32Search in Google Scholar

7. Cani, P. D., 2018: A brief overview of the mechanisms of action by which traditional and next-generation probiotics affect host health. Gut Microbiota, Research and Practice, https://www.gutmicrobiotaforhealth.com/en/brief-overview-mechanisms-action-traditional-next-generation-probiotics-affect-host-health/.Search in Google Scholar

8. Cornick, S., Tawiah, A., Chadee, K., 2015: Roles and regulation of the mucus barrier in the gut. Tissue Barriers, 3, e982426.10.4161/21688370.2014.982426Search in Google Scholar

9. Čapkovičová, A., Maková, Z., Piešová, E., Faix, Š., Alves, A., Faixová, Z., 2012: Evaluation of effects of Thymus vulgaris extract on metabolism and gut mucus in chicks. Folia Veterinaria, 56, 21—27.Search in Google Scholar

10. Čapkovičová, A., Maková, Z., Piešová, E., Alves, A., Faix, Š., Faixová, Z., 2014: Evaluation of the effects of Salvia officinalis essential oil on plasma biochemistry, gut mucus and quantity of acidic and neutral mucins in the chicken gut. Acta Vet. Beograd, 64, 138—148.10.2478/acve-2014-0014Search in Google Scholar

11. Demeterová, M., Šamudovská, A., Faixová, Z. Maková, Z., Piešová, E., Bujňák, L., 2012: Purified β–glucan from oyster mushrooms (pleurotus ostreatus l.) in the diets for chickens: performance, mucus formation and fermentation in the caecum. Folia Veterinaria, 56, 45—46.Search in Google Scholar

12. Deplancke, B., Gaskins, H. R., 2001: Microbial modulation of innate defense: goblet cells and the intestinal mucus layer. Am. J. Clin. Nutr., 73, 1131S—1141S.10.1093/ajcn/73.6.1131SSearch in Google Scholar

13. Dohrman, A., Miyata, S., Gallup, M., 1998: Mucin gene (MUC2 and MUC5AC upregulation by gram-positive and gram-negative bacteria. Biochim. Biophys. Acta, 1406, 251—259.10.1016/S0925-4439(98)00010-6Search in Google Scholar

14. Donaldson, G. P., Lee, S. M., Mazmanian, S. K., 2016: Gut biogeography of the bacterial microbiota. Nature Reviews Microbiology, 14, 20—32.10.1038/nrmicro3552483711426499895Search in Google Scholar

15.https://ec.europa.eu/food/safety/animal-feed/feed-additives_en.Search in Google Scholar

16. Ermund, A., Schütte, A., Johansson, M. E. V., Gustafsson, J. K., Hansson, G. C., 2013: Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer’s patches. Am. J. Physiol. Gastrointest. Liver Physiol., 305, G341—G347.10.1152/ajpgi.00046.2013376124723832518Search in Google Scholar

17. Faixová, Z., Piešová, E., Maková, Z., Levkut, M. jr., Pistl, J., Lauková, A., et al., 2012: Effect of dietary probiotic and plant extract supplementation on mucin dynamics in the chicken intestine and on performance of chickens. Folia Veterinaria, 56 (Supplementum II), 15—16.Search in Google Scholar

18. Hansson, G. C., 2012: Role of mucus layers in gut infection and inflammation. Curr. Opin. Microbiol., 15, 57—62.10.1016/j.mib.2011.11.002371645422177113Search in Google Scholar

19. Hashemi, R., Davoodi, H., 2011: Herbal plant and their derivatives as growth and health promoters in animal nutrition. Veterinary Research Communications, 35, 169—180.10.1007/s11259-010-9458-221213046Search in Google Scholar

20. Chen, Y. P., Cheng, Y. F., Li, X. H., Yang, W. L., Wen, C., Zhuang, S., Zhou, Y. M., 2017: Effects of threonine supplementation on the growth performance, immunity, oxidative status, intestinal integrity, and barrier function of broilers at the early age. Poultry Science, 96, 405—413.10.3382/ps/pew24027418662Search in Google Scholar

21. Cho, Y., Yoon, K. J., 2014: An overview of calf diarrhea — infectious etiology, diagnosis, and intervention. J. Vet. Sci., 15, 1—17.10.4142/jvs.2014.15.1.1397375224378583Search in Google Scholar

22. Jakobsson, H. E., Rodríguez-Piñeiro, A. M., Schütte, A., Ermund, A., Boysen, P., Bemark, M., et al., 2015: The composition of the gut microbiota shapes the colon mucus barrier. EMBO reports, 16, 164—177.10.15252/embr.201439263432874425525071Search in Google Scholar

23. Johansson, M. E. V., Ambort, D., Pelaseyed, T., Schutte, A., Gustafsson, J. K., Ermund, A., et al., 2011a: Composition and functional role of the mucus layers in the intestine. Cellular and Molecular Life Sciences, 68, 3635—3641.10.1007/s00018-011-0822-321947475Search in Google Scholar

24. Johansson, M. E. V., Holmén-Larsson, D. B., Hansson, G. C., 2011b: The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc. Natl. Acad. Sci. USA, 108, 4659—4665.10.1073/pnas.1006451107306360020615996Search in Google Scholar

25. Johansson, M. E. V., Sjovall, H., Hansson, G. C., 2013: The gastrointestinal mucus system in health and disease. Natur. Rev. Gastroenterol. Hepatol., 10, 352—361.10.1038/nrgastro.2013.35375866723478383Search in Google Scholar

26. Kim, Y. S., Ho, S. B., 2010: Intestinal Goblet cells and mucins in health and disease: Recent insights and progress. Curr. Gastroenterol. Rep., 12, 319—330.10.1007/s11894-010-0131-2Search in Google Scholar

27. Li, H., Limenitakis, J. P., Fuhrer, T., Geuking, M. B., Lawson, M. A., Wyss, M., et al., 2015: The outer mucus layer hosts a distinct intestinal microbial niche. Nature Communications, 6, 8292.10.1038/ncomms9292Search in Google Scholar

28. Licois, D., Guillo, J. F., Mouline, C., Reynaud, A., 1992: Susceptibility of the rabbit to an enteropathogenic strain of Escherichia coli 0103: effect of animals’ age. Ann. Rech. Vet., 23, 225—232.Search in Google Scholar

29. Lin, A., 2010:Characterization of Murine Intestinal Mucus Layer Gene Expression During Postnatal Maturation (Thesis), University of Toronto, 101 pp.Search in Google Scholar

30. Loeffler, S. L., 2014: Effects of Probiotic and Prebiotic Supplementation in Turkey Poults on Intestinal Morphology and MUC2 Gene Expression (Thesis), The Ohio State University, 50 pp.Search in Google Scholar

31. Macfarlane, S., Macfarlane, G. T., 2006: Composition and metabolic activities of bacterial biofilms colonizing food residues in the human gut. App. Environ. Microbiol., 72, 6204—6211.10.1128/AEM.00754-06Search in Google Scholar

32. Mah, T. F. C., O’Toole, G. A., 2001: Mechanisms of biofilm resistance to antimicrobial agents. Trends in Microbiology, 9, 34—39.10.1016/S0966-842X(00)01913-2Search in Google Scholar

33. Major, P., Revajová, V., Levkut, M., Ševčíková, Z., Spišáková, V., Faixová, Z., et al., 2011: Intestinal mucin dynamic and leukocytic responses of chickens infected with Eimeria acervulina and fed oregano supplemented diet. Acta Vet. Brno, 80, 147—156.10.2754/avb201180020147Search in Google Scholar

34. Maková, Z., Piešová, E., Faixová, Z., Levkut, M. jr, Lauková, A., Pistl, J., 2009: The effect of S. enteritidis PT4 and E. faecium EF55 on chicken intestine mucus production and some haematological parameters. Folia Veterinaria, 53, 162—164.Search in Google Scholar

35. Mattar, A. F., Teitelbaum, D. H., Drongowski, R. A., Yongyi, F., Harmon, C. M., Coran, A. G., 2002: Probiotics up-regulate MUC-2 mucin gene expression in a Caco-2 cell-culture model. Pediatr. Surg. Int., 18, 586—90.10.1007/s00383-002-0855-7Search in Google Scholar

36. Mack, D. R., Michail, S., Wei, S., McDougall, L., 1999: Probiotics inhibit enteropathogenic E. coli adherence in vitro by including intestinal mucin gene expression. Am. J. Physiol. Gastrointest. Liver Physiol., 276, 39—44.10.1152/ajpgi.1999.276.4.G941Search in Google Scholar

37. Moghaddam, H. S., Moghaddam, H. N., Kermanshahi, H., Mosavi, A. H., Raji, A., 2011: The effect of threonine on mucin 2 gene expression, intestinal histology and performance of broiler chicken. Ital. J. Anim. Sci., 10, e14.10.4081/ijas.2011.e14Search in Google Scholar

38. Montagne, L., Pluske, J. R., Hampson, D. J., 2003: A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young nonruminant animals. Anim. Feed Sci. Technol., 108, 95—117.10.1016/S0377-8401(03)00163-9Search in Google Scholar

39. Oh, N. S., Lee, J. Y., Lee, J. M., Lee, K. W., Kim, Y., 2017: Mulberry leaf extract fermented with Lactobacillus acidophilus A4 ameliorates 5-fluorouracil-induced intestinal mucositis in rats. Lett. Appl. Microbiol., 64, 459—468.10.1111/lam.1274128378512Search in Google Scholar

40. Sangani, A. K., Masoudi, A. A., Hosseini, S. A., 2014: The effects of herbal plants on Mucin 2 gene expression and performance in ascetic broilers. Iranian Journal of Veterinary Medicine, 8, 47—52.Search in Google Scholar

41. Smirnov, A., Tako, E., Ferket, P. R., Uni, Z., 2006: Mucin gene expression and mucin content in the chicken intestinal goblet cells are affected by in ovo feeding of carbohydrates. Poult. Sci. J., 85, 669—673.10.1093/ps/85.4.66916615351Search in Google Scholar

42. Sørensen, M. T., Vestergaard, E. M., Jensen, S. K., Lauridsen, C., Højsgaard, S., 2009: Performance and diarrhoea in piglets following weaning at seven weeks of age: Challenge with E. coli O 149 and effect of dietary factors. Livestock Science, 123, 314—321.10.1016/j.livsci.2008.12.001Search in Google Scholar

43. Strompfová, V., Lauková A., 2007:In vitro study on bacteriocin production of Enterococci associated with chickens. Anaerobe, 13, 228—237.10.1016/j.anaerobe.2007.07.00217884622Search in Google Scholar

44. Ševčíková, Z., Blanár, J., Lauková, A., Revajová, V., Strompfová, V., Levkut, M., 2016: Effect of Enterococcus faecium EF 55 on morphometry and proliferative activity of intestinal mucosa in broilers infected with Salmonella enteritidis. J. Vet. Res., 60, 261—265.10.1515/jvetres-2016-0040Search in Google Scholar

45. Van den Steen, P., Rudd, P. M., Dwek, R. A., Opdenakker, G., 1998: Concepts and Principles of O-Linked Glycosylation. Critical Reviews in Biochemistry and Molecular Biology, 33, 151—208.10.1080/104092398912041989673446Search in Google Scholar

46. Wang, L., Cao, H., Liu, L., Wang, B., Walker, W. A., Acra, S. A., Yan, F., 2014: Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, and Lactobacillus rhamnosus GG-derived protein. J. Biol. Chem., 289, 20234—20244.10.1074/jbc.M114.553800410633924895124Search in Google Scholar

47. Wilson, M., 2002: Bacterial adhesion to host tissues: mechanisms and consequences. Adv. Mol. Cell. Microb., 1, 1—39.10.1017/CBO9780511541575Search in Google Scholar