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Time to recovery from severe pneumonia and its predictors among pediatric patients admitted in Mizan-Tepi University Teaching Hospital, South West Ethiopia, 2022

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Sep 16, 2024

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Figure 1.

Kaplan–Meier survival estimate graph overall median recovery time among children admitted from 01 January 2019 to 30 December 2021 at pediatric ward of MTUTH, Ethiopia, 2022. MTUTH, Mizan-Tepi University Teaching Hospital.
Kaplan–Meier survival estimate graph overall median recovery time among children admitted from 01 January 2019 to 30 December 2021 at pediatric ward of MTUTH, Ethiopia, 2022. MTUTH, Mizan-Tepi University Teaching Hospital.

Figure 2.

Overall Kaplan–Meier survival and failure estimate of children admitted from 01 January 2019 to 30 December 2021 at pediatric ward of MTUTH, Ethiopia, 2022. MTUTH, Mizan-Tepi University Teaching Hospital.
Overall Kaplan–Meier survival and failure estimate of children admitted from 01 January 2019 to 30 December 2021 at pediatric ward of MTUTH, Ethiopia, 2022. MTUTH, Mizan-Tepi University Teaching Hospital.

Nutritional status and feeding characteristics of children admitted from 01 January 2019 to 30 December 2021 at the pediatric ward of MTUTH, Ethiopia, 2022 (N = 591)_

Characteristics Total, N (%) Outcome variable, N (%)
Censored, N = 50 Recovered, N = 541
WFA
    Normal 509 (86.13) 41 (8.1) 468 (91.9)
    Underweight 82 (13.87) 9 (11.0) 73 (89.0)
WFH
    Normal 497 (84.09) 41 (8.2) 456 (91.8)
    Wasted 94 (15.91) 9 (9.6) 85 (90.4)
HFA
    Normal 492 (83.25) 36 (7.3) 456 (92.7)
    Stunted 99 (16.75) 14 (14.1) 85 (85.9)
Mode of infant feeding
    Breast milk 379 (64.13) 33 (8.7) 346 (91.3)
    Formula 30 (5.08) 2 (6.7) 28 (93.3)
    Cow milk 182 (30.80) 15 (8.2) 167 (91.8)
Exclusive breastfeeding
    Yes 397 (67.17) 37 (9.3) 360 (90.7)
    No 194 (32.83) 13 (6.7) 181 (93.3)

Clinical and therapeutic regimen characteristics of children admitted from 01 January 2019 to 30 December 2021 at the pediatric ward of MTUTH, Ethiopia, 2022 (N = 591)_

Characteristics Total, N (%) Outcome variable, N (%)
Censored, N = 50 Recovered, N = 541
Danger sign during admission
    No 115 (19.46) 2 (1.7) 113 (98.3)
    Yes 476 (80.54) 48 (10.1) 428 (89.9)
Hypoxia during admission
    No 343 (58.04) 5 (1.5) 338 (98.5)
    Yes 248 (41.96) 45 (18.1) 203 (81.9)
Fever during admission
    No 209 (35.36) 19 (9.1) 190 (90.9)
    Yes 382 (64.64) 31 (8.1) 351 (91.9)
Respiratory distress
    No 187 (31.64) 4 (2.1) 183 (97.9)
    Yes 404 (68.36) 46 (11.4) 358 (88.6)
Vomiting everything
    No 483 (81.73) 36 (7.5) 447 (92.5)
    Yes 108 (18.27) 14 (13.0) 94 (87.0)
Altered consciousness
    No 539 (91.20) 31 (5.8) 508 (94.2)
    Yes 52 (8.80) 19 (36.5) 33 (63.5)
Inability to breastfeeding or drink
    No 363 (61.42) 9 (2.5) 354 (97.5)
    Yes 228 (38.58) 41 (18.0) 187 (82.0)
Abnormal body movement/convulsion
    No 589 (99.66) 48 (8.1) 541 (91.9)
    Yes 2 (0.34) 2 (100.0) -
Antibiotic first given
    Ceftriaxone 338 (57.19) 29 (8.6) 309 (91.4)
    Crystalline penicillin 45 (7.61) 2 (4.4) 43 (95.6)
    Ampicillin and gentamicin 208 (35.19) 19 (9.1) 189 (90.9)
Antibiotic change after admission
    No 267 (45.18) 12 (4.5) 255 (95.5)
    Yes 324 (54.82) 38 (11.7) 286 (88.3)
Co-morbidity
    No 395 (66.84) 32 (8.1) 363 (91.9)
    Yes 196 (33.16) 18 (9.2) 178 (90.8)
Birth weight during birth (g)
    <2500 61 (10.32) 4 (6.6) 57 (93.4)
    >2500 530 (89.68) 46 (8.7) 484 (91.3)
Gestational age (weeks)
    <37 84 (14.21) 8 (9.5) 76 (90.5)
    37–42 507 (85.79) 42 (8.3) 465 (91.7)
Presentation to seek care (days)
    5 203 (34.35) 32 (15.8) 171 (84.2)
    <5 388 (65.65) 18 (4.6) 370 (95.4)

Socio-demographic characteristics of children admitted from 01 January 2019 to 30 December 2021 at the pediatric ward of MTUTH, Ethiopia, 2022 (N = 591)_

Characteristics Total, N (%) Outcome variable, N (%)
Censored, N = 50 Recovered, N = 541
Sex
    Male 359 (60.74) 18 (5.0) 341 (95.0)
    Female 232 (39.26) 32 (13.8) 200 (86.2)
Age (years)
    <1 308 (52.12) 33 (10.7) 275 (89.3)
    1–5 170 (28.76) 9 (5.3) 161 (94.7)
    5–14 113 (19.12) 8 (7.1) 105 (92.9)
Residency
    Urban 211 (35.70) 11 (5.2) 200 (94.8)
    Rural 380 (64.30) 39 (10.3) 341 (89.7)

Incidence rate and median recovery time of children with severe pneumonia in each age group category admitted from 01 January 2019 to 30 December 2021 at NICU of MTUTH Hospital, Ethiopia, 2022_

Birthweight category Events Total time at risk Incidence rate/100 (95% CI) Median recovery time
<1 year (n = 308) 275 1224 22.47 (95% CI: 19.96–25.28) 4
1–5 years (n = 170) 161 618 26.10 (95% CI: 22.32–30.40) 4
>5 years (n = 113) 105 403 26. 05 (95% CI: 21.52–31.54) 3

Results of the bivariate and multivariable analysis of children admitted from 01 January 2019 to 30 December 2021 at the pediatric ward of the MTUTH, Ethiopia, 2022_

Predictor CHR (95% CI) AHR (95% CI) P-value
Age (years)
    <1 0.83 (0.66–1.04) 0.92 (0.72–1.17) 0.496
    1–5 0.98 (0.77–1.25) 0.96 (0.74–1.24) 0.754
    >5 1 1.00
Respiratory distress
    No 1 1.00
    Yes 0.81 (0.68–0.97) 0.95 (0.78–1.17) 0.642
Vomiting everything
    No 1 1.00
    Yes 0.79 (0.63–0.99) 0.84 (0.67–1.06) 0.142
Antibiotic changed
    No 1 1.00
    Yes 0.89 (0.76–1.06) 0.88 (0.74–1.05) 0.148
Infant feeding
    Breast milk 1 1.00
    Formula 1.65 (1.12–2.44) 1.29 (0.81–2.03) 0.279
    Cow milk 1.03 (0.85–1.24) 0.81 (0.64–1.04) 0.102
Exclusive Breastfeeding
    Yes 1 1.00
    No 1.18 (0.98–1.41) 1.3 (1.03–1.66) 0.025*
Altered level of consciousness
    No 1 1.00
    Yes 0.64 (0.45–0.92) 0.71 (0.49–1.04) 0.077
Unable to suck
    No 1 1.00
    Yes 0.75 (0.63–0.89) 0.81 (0.65–0.99) 0.048*
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Assistive Professions, Nursing