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Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge†

Ning Liu
Ning Liu
, 
Hong Lu
Hong Lu
, 
Xiao-Qing Yi
Xiao-Qing Yi
, 
Yang Yang
Yang Yang
 and 
Xiao-Hong Huang
Xiao-Hong Huang
   | Aug 03, 2022
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Article Category: Original Article
Published Online: Aug 03, 2022
Page range: 155 - 163
Received: Dec 14, 2021
Accepted: Feb 24, 2022
DOI: https://doi.org/10.2478/fon-2022-0017
Keywords
© 2022 Ning Liu et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Association matrix of protective training for AD exposure, protective knowledge, using warning labels and using protective masks.
Association matrix of protective training for AD exposure, protective knowledge, using warning labels and using protective masks.

Figure 2

Mediation effect of protective knowledge on the association of protective training regarding AD exposure with warning label use.Note: The proportion of mediation = 23.4%.
Mediation effect of protective knowledge on the association of protective training regarding AD exposure with warning label use.Note: The proportion of mediation = 23.4%.

Figure 3

Mediation effect of protective knowledge on the association of protective training regarding AD exposure with protective mask use.Note: The proportion of mediation =27.2%.
Mediation effect of protective knowledge on the association of protective training regarding AD exposure with protective mask use.Note: The proportion of mediation =27.2%.

Association between protective training regarding AD exposure, protective knowledge, and use of warning labels.

Items Protective knowledge (M, β, 95% CI) Warning label use (Y, OR, 95% CI)
Model 1X→M Model 2X→Y Model 3X+M→Y
Protective training (X)
  No Reference Reference Reference
  Yes 0.361 (0.173, 0.550)*** 4.270 (1.424, 12.806)** 3.762 (1.242, 11.396)*
Protective knowledge (M) 1.751 (1.019, 3.010)*

General characteristics of the participants.

Characteristics Number of participants, n (%) Using warning labels Using protective masks
Yes, n (%) No, n (%) χ2/t P Single-layer surgical mask, n (%) Double-layer surgical mask, n (%) N95, n (%) 3M, n (%) χ2/F P
Age (years, Mean (SD)) 30.19 (6.24) 32.35 (7.27) 29.87 (6.02) 2.36a 0.019 30.19 (5.79) 30.63 (6.43) 29.92 (6.62) 28.92 (6.63) 0.37b 0.775
BMI (kg/m2) 0.01c 0.996 0.30d 0.583
  <18.5 62 (20.3) 8 (20.0) 54 (20.4) 23 (20.2) 19 (20.1) 15 (16.9) 5 (41.7)
  18.5–23.9 206 (67.5) 27 (67.5) 179 (67.5) 82 (71.9) 58 (64.4) 60 (67.4) 6 (50.0)
  ≥24 37 (12.1) 5 (12.5) 32 (12.1) 9 (7.9) 13 (14.4) 14 (15.7) 1 (8.3)
Length of service (years) 4.73c 0.094 1.00d 0.317
  <3.81 100 (32.8) 8 (20.0) 92 (34.7) 36 (31.6) 24 (26.7) 34 (38.2) 6 (0.5)
  3.81–10.27 101 (33.1) 13 (32.5) 88 (33.2) 38 (33.3) 36 (40.0) 24 (27.0) 3 (0.25)
  >10.27 104 (34.1) 19 (47.5) 85 (32.1) 40 (35.1) 30 (33.3) 31 (34.8) 3 (0.25)
Married 3.91c 0.048 1.15d 0.284
  No 155 (50.8) 14 (35.0) 141 (53.2) 56 (49.1) 42 (46.7) 50 (56.2) 7 (58.3)
  Yes 150 (49.2) 26 (65.0) 124 (46.8) 58 (50.9) 48 (53.3) 39 (43.8) 5 (41.7)
Education (Years) 2.37c 0.124 3.61d 0.057
  <16 80 (26.2) 6 (15.0) 74 (27.9) 22 (19.3) 26 (28.9) 29 (32.6) 3 (25.0)
  ≥16 225 (73.8) 34 (85.0) 191 (72.1) 92 (80.7) 64 (71.1) 60 (67.4) 9 (75.0)
Department 18.91c <0.001 0.60d 0.439
  Gynaecology 61 (33.1) 17 (42.5) 84 (31.7) 32 (28.1) 34 (37.8) 34 (38.2) 1 (8.3)
  Oncology 143 (20.0) 16 (40.0) 45 (17.0) 20 (17.5) 21 (23.3) 18 (20.2) 2 (16.7)
  Other 101 (46.9) 7 (17.5) 136 (51.3) 62 (54.4) 35 (38.9) 37 (41.6) 9 (75.0

Association between protective training regarding AD exposure, protective knowledge, and using protective masks.

Items Protective knowledge (M, β, 95% CI) Protective mask use (Y, OR, 95% CI)
Model 1X→M Model 2X→Y Model 3X+M→Y
Protective training (X)
  No Reference Reference Reference
  Yes 0.361 (0.173, 0.550)*** 2.087 (1.314, 3.317)** 1.836 (1.145, 2.944)*
Protective knowledge (M) 1.545 (1.165, 2.047)*
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