[
Althammer F. Heralding a new era of oxytocinergic research: New tools, new problems? J Neuroendocrinol 35, e13333, 2023.
]Search in Google Scholar
[
Amato S, Averna M, Guidolin D, Ceccoli C, Gatta E, Candiani S, Pedrazzi M, Capraro M, Maura G, Agnati LF, Cervetto C, Marcoli M. Heteromerization of dopamine D2 and oxytocin receptor in adult striatal astrocytes. Int J Mol Sci 24, 4677, 2023.
]Search in Google Scholar
[
Babij R, Ferrer C, Donatelle A, Wacks S, Buch AM, Niemeyer JE, Ma H, Duan ZRS, Fetcho RN, Che A, Otsuka T, Schwartz TH, Huang BS, Liston C, De Marco Garcia NV. Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex. Neuron 111, 256–274, 2023.
]Search in Google Scholar
[
Babinska K, Tomova A, Celusakova H, Babkova J, Repiska G, Kubranska A, Filcikova D, Siklenkova L, Ostatnikova D. Fecal calprotectin levels correlate with main domains of the autism diagnostic interview-revised (ADI-R) in a sample of individuals with autism spectrum disorders from Slovakia. Physiol Res 66, S517–S522, 2017.
]Search in Google Scholar
[
Bakos J, Zatkova M, Bacova Z, Ostatnikova D. The role of hypothalamic neuropeptides in neurogenesis and neurito-genesis. Neural Plast 2016, 3276383, 2016.
]Search in Google Scholar
[
Bariselli S, Tzanoulinou S, Glangetas C, Prevost-Solie C, Pucci L, Viguie J, Bezzi P, O’Connor EC, Georges F, Luscher C, Bellone C. SHANK3 controls maturation of social reward circuits in the VTA. Nat Neurosci 19, 926–934, 2016.
]Search in Google Scholar
[
Barnes SA, Pinto-Duarte A, Kappe A, Zembrzycki A, Metzler A, Mukamel EA, Lucero J, Wang X, Sejnowski TJ, Markou A, Behrens MM. Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders. Mol Psychiatry 20, 1161–1172, 2015.
]Search in Google Scholar
[
Baskerville TA, Douglas AJ. Dopamine and oxytocin interactions underlying behaviors: potential contributions to behavioral disorders. CNS Neurosci Ther 16, e92–e123, 2010.
]Search in Google Scholar
[
Ben-Ari Y. Excitatory actions of gaba during development: the nature of the nurture. Nat Rev Neurosci 3, 728–739, 2002.
]Search in Google Scholar
[
Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nat Commun 13, 3328, 2022.
]Search in Google Scholar
[
Bissonette GB, Roesch MR. Development and function of the midbrain dopamine system: what we know and what we need to. Genes Brain Behav 15, 62–73, 2016.
]Search in Google Scholar
[
Bolneo E, Chau PYS, Noakes PG, Bellingham MC. Investigating the role of GABA in neural development and disease using mice lacking GAD67 or VGAT genes. Int J Mol Sci 23, 7965, 2022.
]Search in Google Scholar
[
Bowen MT, Peters ST, Absalom N, Chebib M, Neumann ID, McGregor IS. Oxytocin prevents ethanol actions at δ subunit-containing GABAA receptors and attenuates ethanol-induced motor impairment in rats. Proc Natl Acad Sci U S A 112, 3104–3109, 2015.
]Search in Google Scholar
[
Brandenburg C, Soghomonian JJ, Zhang K, Sulkaj I, Randolph B, Kachadoorian M, Blatt GJ. Increased dopamine type 2 gene expression in the dorsal striatum in individuals with autism spectrum disorder suggests alterations in indirect pathway signaling and circuitry. Front Cell Neurosci 14, 577858, 2020.
]Search in Google Scholar
[
Bukatova S, Renczes E, Reichova A, Filo J, Sadlonova A, Mravec B, Ostatnikova D, Bakos J, Bacova Z. Shank3 deficiency is associated with altered profile of neurotransmission markers in pups and adult mice. Neurochem Res 46, 3342–3355, 2021.
]Search in Google Scholar
[
Busnelli M, Chini B. Molecular basis of oxytocin receptor signalling in the brain: What we know and what we need to know. Curr Top Behav Neurosci 35, 3–29, 2018.
]Search in Google Scholar
[
Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereoty-pies and Rett syndrome phenotypes. Nature 468, 263–269, 2010.
]Search in Google Scholar
[
Clements CC, Zoltowski AR, Yankowitz LD, Yerys BE, Schultz RT, Herrington JD. Evaluation of the social motivation hypothesis of autism: A systematic review and meta-analysis. JAMA Psychiatry 75, 797–808, 2018.
]Search in Google Scholar
[
Coghlan S, Horder J, Inkster B, Mendez MA, Murphy DG, Nutt DJ. GABA system dysfunction in autism and related disorders: from synapse to symptoms. Neurosci Biobehav Rev 36, 2044–2055, 2012.
]Search in Google Scholar
[
DeMayo MM, Harris AD, Song YJC, Pokorski I, Thapa R, Patel S, Ambarchi Z, Thomas EE, Hickie IB, Guastella AJ. Age-related parietal GABA alterations in children with autism spectrum disorder. Autism Res 14, 859–872, 2021.
]Search in Google Scholar
[
Dickinson A, Jones M, Milne E. Measuring neural excitation and inhibition in autism: Different approaches, different findings and different interpretations. Brain Res 1648, 277–289, 2016.
]Search in Google Scholar
[
Dougnon G, Matsui H. Modelling autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) using mice and zebrafish. Int J Mol Sci 23, 7550, 2022.
]Search in Google Scholar
[
Eiden LE, Hernandez VS, Jiang SZ, Zhang L. Neuropeptides and small-molecule amine transmitters: cooperative signaling in the nervous system. Cell Mol Life Sci 79, 492, 2022.
]Search in Google Scholar
[
Eyles D, Feldon J, Meyer U. Schizophrenia: do all roads lead to dopamine or is this where they start? Evidence from two epidemiologically informed developmental rodent models. Transl Psychiatry 2, e81, 2012.
]Search in Google Scholar
[
Ferguson JN, Aldag JM, Insel TR, Young LJ. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J Neurosci 21, 8278–8285, 2001.
]Search in Google Scholar
[
Fernandez M, Mollinedo-Gajate I, Penagarikano O. Neural circuits for social cognition: Implications for autism. Neuroscience 370, 148–162, 2018.
]Search in Google Scholar
[
Fung LK, Flores RE, Gu M, Sun KL, James D, Schuck RK, Jo B, Park JH, Lee BC, Jung JH, Kim SE, Saggar M, Sacchet MD, Warnock G, Khalighi MM, Spielman D, Chin FT, Hardan AY. Thalamic and prefrontal GABA concentrations but not GABAA receptor densities are altered in high-functioning adults with autism spectrum disorder. Mol Psychiatry 26, 1634–1646, 2021.
]Search in Google Scholar
[
Gaertner Z, Azcorra M, Dombeck DA, Awatramani R. Molecular heterogeneity in the substantia nigra: A roadmap for understanding PD motor pathophysiology. Neurobiol Dis 175, 105925, 2022.
]Search in Google Scholar
[
Gordon I, Martin C, Feldman R, Leckman JF. Oxytocin and social motivation. Dev Cogn Neurosci 1, 471–493, 2011.
]Search in Google Scholar
[
Gordon-Fennell A, Stuber GD. Illuminating subcortical GABAergic and glutamatergic circuits for reward and aversion. Neuropharmacology 198, 108725, 2021.
]Search in Google Scholar
[
Grapel JN, Cicchetti DV, Volkmar FR. Sensory features as diagnostic criteria for autism: sensory features in autism. Yale J Biol Med 88, 69–71, 2015.
]Search in Google Scholar
[
Grinevich V, Ludwig M. The multiple faces of the oxytocin and vasopressin systems in the brain. J Neuroendocrinol 33, e13004, 2021.
]Search in Google Scholar
[
Hanaie R, Mohri I, Kagitani-Shimono K, Tachibana M, Matsuzaki J, Hirata I, Nagatani F, Watanabe Y, Katayama T, Taniike M. Aberrant cerebellar-cerebral functional connectivity in children and adolescents with autism spectrum disorder. Front Hum Neurosci 12, 454, 2018.
]Search in Google Scholar
[
Havranek T, Mihalj D, Bacova Z, Bakos J. Oxytocin action on components of endoplasmic reticulum in hippocampal neuronal cells. Neurosci Lett 792, 136971, 2023.
]Search in Google Scholar
[
Horder J, Petrinovic MM, Mendez MA, Bruns A, Takumi T, Spooren W, Barker GJ, Kunnecke B, Murphy DG. Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models. Transl Psychiatry 8, 106, 2018.
]Search in Google Scholar
[
Hung LW, Neuner S, Polepalli JS, Beier KT, Wright M, Walsh JJ, Lewis EM, Luo L, Deisseroth K, Dolen G, Malenka RC. Gating of social reward by oxytocin in the ventral tegmental area. Science 357, 1406–1411, 2017.
]Search in Google Scholar
[
Inoue K, Ford CL, Horie K, Young LJ. Oxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine system. J Comp Neurol 530, 2881–2900, 2022.
]Search in Google Scholar
[
Jing P, Shan Q. Exogenous oxytocin microinjection into the nucleus accumbens shell attenuates social dominance in group-housed male mice. Physiol Behav 269, 114253, 2023.
]Search in Google Scholar
[
John S, Jaeggi AV. Oxytocin levels tend to be lower in autistic children: A meta-analysis of 31 studies. Autism 25, 2152–2161, 2021.
]Search in Google Scholar
[
Kana RK, Keller TA, Minshew NJ, Just MA. Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networks. Biol Psychiatry 62, 198–206, 2007.
]Search in Google Scholar
[
Kosillo P, Bateup HS. Dopaminergic dysregulation in syndromic autism spectrum disorders: Insights from genetic mouse models. Front Neural Circuits 15, 700968, 2021.
]Search in Google Scholar
[
Lefevre A, Benusiglio D, Tang Y, Krabichler Q, Charlet A, Grinevich V. Oxytocinergic feedback circuitries: An anatomical basis for neuromodulation of social behaviors. Front Neural Circuits 15, 688234, 2021.
]Search in Google Scholar
[
Leonzino M, Busnelli M, Antonucci F, Verderio C, Mazzanti M, Chini B. The timing of the excitatory-to-inhibitory GABA switch is regulated by the oxytocin receptor via KCC2. Cell Rep 15, 96–103, 2016.
]Search in Google Scholar
[
Lestanova Z, Bacova Z, Kiss A, Havranek T, Strbak V, Bakos J. Oxytocin increases neurite length and expression of cytoskeletal proteins associated with neuronal growth. J Mol Neurosci 59, 184–192, 2016.
]Search in Google Scholar
[
Li LF, Yuan W, He ZX, Wang LM, Jing XY, Zhang J, Yang Y, Guo QQ, Zhang XN, Cai WQ, Hou WJ, Jia R, Tai FD. Involvement of oxytocin and GABA in consolation behavior elicited by socially defeated individuals in mandarin voles. Psychoneuroendocrinology 103, 14–24, 2019.
]Search in Google Scholar
[
Lukas M, Toth I, Veenema AH, Neumann ID. Oxytocin mediates rodent social memory within the lateral septum and the medial amygdala depending on the relevance of the social stimulus: male juvenile versus female adult conspecifics. Psychoneuroendocrinology 38, 916–926, 2013.
]Search in Google Scholar
[
Ma SY, Kwan KM. Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. Behav Brain Res 428, 113896, 2022.
]Search in Google Scholar
[
Maier S, Duppers AL, Runge K, Dacko M, Lange T, Fangmeier T, Riedel A, Ebert D, Endres D, Domschke K, Perlov E, Nickel K, Tebartz van Elst L. Increased prefrontal GABA concentrations in adults with autism spectrum disorders. Autism Res 15, 1222–1236, 2022.
]Search in Google Scholar
[
Maniezzi C, Talpo F, Spaiardi P, Toselli M, Biella G. Oxytocin increases phasic and tonic GABAergic transmission in CA1 region of mouse hippocampus. Front Cell Neurosci 13, 178, 2019.
]Search in Google Scholar
[
Manz KM, Baxley AG, Zurawski Z, Hamm HE, Grueter BA. Heterosynaptic GABAB receptor function within feedforward microcircuits gates glutamatergic transmission in the nucleus accumbens core. J Neurosci 39, 9277–9293, 2019.
]Search in Google Scholar
[
Marotta R, Risoleo MC, Messina G, Parisi L, Carotenuto M, Vetri L, Roccella M. The neurochemistry of autism. Brain Sci 10, 163, 2020.
]Search in Google Scholar
[
Martella G, Meringolo M, Trobiani L, De Jaco A, Pisani A, Bonsi P. The neurobiological bases of autism spectrum disorders: the R451C-neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum. Eur J Neurosci 47, 701–708, 2018.
]Search in Google Scholar
[
Mehta TR, Murala S, Siddiqui J. Dopamine. In: Neurochemistry in Clinical Practice. (ed P.C. Bollu), Springer, Cham, Switzerland, 2022.
]Search in Google Scholar
[
Miranda-Barrientos J, Chambers I, Mongia S, Liu B, Wang HL, Mateo-Semidey GE, Margolis EB, Zhang S, Morales M. Ventral tegmental area GABA, glutamate, and glutamate-GABA neurons are heterogeneous in their electrophysiological and pharmacological properties. Eur J Neurosci 54, 4061–4084, 2021.
]Search in Google Scholar
[
Nieoullon A, Coquerel A. Dopamine: a key regulator to adapt action, emotion, motivation and cognition. Curr Opin Neurol 16, S3–S9, 2003.
]Search in Google Scholar
[
Nunes AR, Gliksberg M, Varela SAM, Teles M, Wircer E, Blechman J, Petri G, Levkowitz G, Oliveira RF. Developmental effects of oxytocin neurons on social affiliation and processing of social information. J Neurosci 41, 8742–8760, 2021.
]Search in Google Scholar
[
Oettl LL, Ravi N, Schneider M, Scheller MF, Schneider P, Mitre M, da Silva Gouveia M, Froemke RC, Chao MV, Young WS, Meyer-Lindenberg A, Grinevich V, Shusterman R, Kelsch W. Oxytocin enhances social recognition by modulating cortical control of early olfactory processing. Neuron 90, 609–621, 2016.
]Search in Google Scholar
[
Paval D. The dopamine hypothesis of autism spectrum disorder: A comprehensive analysis of the evidence. Int Rev Neurobiol 173, 1–42, 2023.
]Search in Google Scholar
[
Paval D, Miclutia IV. The Dopamine hypothesis of autism spectrum disorder revisited: Current status and future prospects. Dev Neurosci 43, 73–83, 2021.
]Search in Google Scholar
[
Paxinos G, Watson C. The rat brain in stereotaxic coordinates. Academic Press, San Diego, USA, 1997.
]Search in Google Scholar
[
Peerboom C, Wierenga CJ. The postnatal GABA shift: A developmental perspective. Neurosci Biobehav Rev 124, 179–192, 2021.
]Search in Google Scholar
[
Rahaman SM, Chowdhury S, Mukai Y, Ono D, Yamaguchi H, Yamanaka A. Functional interaction between GABAergic neurons in the ventral tegmental area and serotonergic neurons in the dorsal raphe nucleus. Front Neurosci 16, 877054, 2022.
]Search in Google Scholar
[
Reichova A, Schaller F, Bukatova S, Bacova Z, Muscatelli F, Bakos J. The impact of oxytocin on neurite outgrowth and synaptic proteins in Magel2-deficient mice. Dev Neurobiol 81, 366–388, 2021.
]Search in Google Scholar
[
Reynolds LM, Flores C. Mesocorticolimbic dopamine pathways across adolescence: diversity in development. Front Neural Circuits 15, 735625, 2021.
]Search in Google Scholar
[
Rigney N, de Vries GJ, Petrulis A, Young LJ. Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities. Endocrinology 163, bqac111, 2022.
]Search in Google Scholar
[
Roberts BM, Lopes EF, Cragg SJ. Axonal modulation of striatal dopamine release by local γ-aminobutyric acid (GABA) signalling. Cells 10, 709, 2021.
]Search in Google Scholar
[
Romero-Fernandez W, Borroto-Escuela DO, Agnati LF, Fuxe K. Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions. Mol Psychiatry 18, 849–850, 2013.
]Search in Google Scholar
[
Roux S, Lohof A, Ben-Ari Y, Poulain B, Bossu JL. Maturation of GABAergic transmission in cerebellar Purkinje cells is sex dependent and altered in the valproate model of autism. Front Cell Neurosci 12, 232, 2018.
]Search in Google Scholar
[
Salamone JD, Pardo M, Yohn SE, Lopez-Cruz L, SanMiguel N, Correa M. Mesolimbic dopamine and the regulation of motivated behavior. Curr Top Behav Neurosci 27, 231–257, 2016.
]Search in Google Scholar
[
Sgado P, Genovesi S, Kalinovsky A, Zunino G, Macchi F, Allegra M, Murenu E, Provenzano G, Tripathi PP, Casarosa S, Joyner AL, Bozzi Y. Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: implications for autism spectrum disorders. Exp Neurol 247, 496–505, 2013.
]Search in Google Scholar
[
Smith AS, Tabbaa M, Lei K, Eastham P, Butler MJ, Linton L, Altshuler R, Liu Y, Wang Z. Local oxytocin tempers anxiety by activating GABAA receptors in the hypothalamic paraventricular nucleus. Psychoneuroendocrinology 63, 50–58, 2016.
]Search in Google Scholar
[
Soden ME, Chung AS, Cuevas B, Resnick JM, Awatramani R, Zweifel LS. Anatomic resolution of neurotransmitter-specific projections to the VTA reveals diversity of GABAergic inputs. Nat Neurosci 23, 968–980, 2020.
]Search in Google Scholar
[
Tang X, Jaenisch R, Sur M. The role of GABAergic signalling in neurodevelopmental disorders. Nat Rev Neurosci 22, 290–307, 2021.
]Search in Google Scholar
[
Tobin VA, Douglas AJ, Leng G, Ludwig M. The involvement of voltage-operated calcium channels in somato-dendritic oxytocin release. PLoS One 6, e25366, 2011.
]Search in Google Scholar
[
Tyzio R, Nardou R, Ferrari DC, Tsintsadze T, Shahrokhi A, Eftekhari S, Khalilov I, Tsintsadze V, Brouchoud C, Chazal G, Lemonnier E, Lozovaya N, Burnashev N, Ben-Ari Y. Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. Science 343, 675–679, 2014.
]Search in Google Scholar
[
Umesawa Y, Matsushima K, Atsumi T, Kato T, Fukatsu R, Wada M, Ide M. Altered GABA concentration in brain motor area is associated with the severity of motor disabilities in individuals with autism spectrum disorder. J Autism Dev Disord 50, 2710–2722, 2020.
]Search in Google Scholar
[
Wu C, Sun D. GABA receptors in brain development, function, and injury. Metab Brain Dis 30, 367–379, 2015.
]Search in Google Scholar
[
Xiao L, Priest MF, Nasenbeny J, Lu T, Kozorovitskiy Y. Biased oxytocinergic modulation of midbrain dopamine systems. Neuron 95, 368–384, 2017.
]Search in Google Scholar
[
Yamasue H, Domes G. Oxytocin and autism spectrum disorders. Curr Top Behav Neurosci 35, 449–465, 2018.
]Search in Google Scholar
[
Yang Y, Wang B, Zhong Z, Chen H, Ding W, Hoi MPM. Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission. Biochem Pharmacol 192, 114711, 2021.
]Search in Google Scholar
[
Yoo T, Cho H, Lee J, Park H, Yoo YE, Yang E, Kim JY, Kim H, Kim E. GABA neuronal deletion of Shank3 exons 14-16 in mice suppresses striatal excitatory synaptic input and induces social and locomotor abnormalities. Front Cell Neurosci 12, 341, 2018.
]Search in Google Scholar
[
Yu X, Ba W, Zhao G, Ma Y, Harding EC, Yin L, Wang D, Li H, Zhang P, Shi Y, Yustos R, Vyssotski AL, Dong H, Franks NP, Wisden W. Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior. Mol Psychiatry 26, 5213–5228, 2021.
]Search in Google Scholar
[
Zatkova M, Reichova A, Bacova Z, Strbak V, Kiss A, Bakos J. Neurite outgrowth stimulated by oxytocin is modulated by inhibition of the calcium voltage-gated channels. Cell Mol Neurobiol 38, 371–378, 2018.
]Search in Google Scholar
[
Zatkova M, Reichova A, Bacova Z, Bakos J. Activation of the oxytocin receptor modulates the expression of synaptic adhesion molecules in a cell-specific manner. J Mol Neurosci 68, 171–180, 2019.
]Search in Google Scholar
[
Zhao H, Mao X, Zhu C, Zou X, Peng F, Yang W, Li B, Li G, Ge T, Cui R. GABAergic system dysfunction in autism spectrum disorders. Front Cell Dev Biol 9, 781327, 2022.
]Search in Google Scholar
[
Zhou Y, Stubbs RJ, Finlayson G. A neurocognitive perspective on the relationship between exercise and reward: Implications for weight management and drug addiction. Appetite 182, 106446, 2023.
]Search in Google Scholar
[
Zhu Y, Li H, Zhou L, Wu JY, Rao Y. Cellular and molecular guidance of GABAergic neuronal migration from an extracortical origin to the neocortex. Neuron 23, 473–485, 1999.
]Search in Google Scholar
