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Evaluation of Dissolution Release Profiles of Nicotine and Three Distinct Flavor Markers in Loose Moist Smokeless Tobacco Products

Fadi Aldeek

Fadi Aldeek

Altria Client Services LLCRichmond, USA
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Aldeek, Fadi
, 
John H. Miller

John H. Miller

Altria Client Services LLCRichmond, USA
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Miller, John H.
 and 
Tim Danielson

Tim Danielson

Altria Client Services LLCRichmond, USA
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Danielson, Tim
  
Aug 10, 2024
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Article Category: Short Communication
Published Online: Aug 10, 2024
Page range: 157 - 163
Received: Feb 15, 2024
Accepted: Apr 24, 2024
DOI: https://doi.org/10.2478/cttr-2024-0005
Keywords
© 2024 Fadi Aldeek et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Figure 1.

UPLC-PDA chromatograms of (A) glycyrrhizic acid, (B) nicotine, (C) methyl salicylate, and (D) ethyl salicylate in fraction 1 from products -C, -A, and -B, respectively. The inserts show the chemical structures of nicotine and the three flavor markers.
UPLC-PDA chromatograms of (A) glycyrrhizic acid, (B) nicotine, (C) methyl salicylate, and (D) ethyl salicylate in fraction 1 from products -C, -A, and -B, respectively. The inserts show the chemical structures of nicotine and the three flavor markers.

Figure 2.

(A) Cumulative release and (B) percent of total dissolution release profiles (n = 12) of nicotine collected from products -A,-B, and -C. (Error Bars ± 1 SD).
(A) Cumulative release and (B) percent of total dissolution release profiles (n = 12) of nicotine collected from products -A,-B, and -C. (Error Bars ± 1 SD).

Figure 3.

(A) Cumulative release and (B) percent of total dissolution release profiles (n = 12) of flavor markers collected from product-A, -B, and -C. (Error Bars ± 1 SD).
(A) Cumulative release and (B) percent of total dissolution release profiles (n = 12) of flavor markers collected from product-A, -B, and -C. (Error Bars ± 1 SD).
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
General Interest, Life Sciences, Life Sciences, other, Physics, Physics, other
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