Evaluation of Presence or Absence of α-Tocopherol and α-Tocopheryl Acetate in Various E-Liquids

1 Centers for Disease Control and Prevention (CDC), Smoking and Tobacco Use: Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products. Available at: https://www.cdc.gov/tobacco/-basic_information/e-cigarettes/severe-lung-disease.html (accessed March, 2021) Centers for Disease Control, Prevention (CDC), Smoking and Tobacco Use Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products Available at: https://www.cdc.gov/tobacco/-basic_information/e-cigarettes/severe-lung-disease.html (accessed March, 2021) Search in Google Scholar

2 Moritz, E.D., L.B. Zapata, A. Lekiachvili, E. Glidden, F.B. Annor, A.K. Werner, E.N. Ussery, M.M. Hughes, A. Kimball, C.L. DeSisto, B. Kenemer, M. Shamout, M.C. Garcia, S. Reagan-Steiner, E.E. Petersen, E.H. Koumans, M.D. Ritchey, B.A. King, C.M. Jones, P.A. Briss, L. Delaney, A. Patel, K.D. Polen, K. Sives, D. Meaney-Delman, and K. Chatham-Stephens: Lung Injury Response Epidemiology / Surveillance Group; Lung Injury Response Epidemiology / Surveillance Task Force. Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injuries – United States, October 2019; MMWR Morb. Mortal. Wkly. Rep. 68 (2019) 985–989. DOI: 10.15585/mmwr.mm6843e1. Erratum in: MMWR Morb. Mortal. Wkly. Rep. 68 (2019) 1170. DOI: 10.15585/mmwr.mm6850a6 MoritzE.D. ZapataL.B. LekiachviliA. GliddenE. AnnorF.B. WernerA.K. UsseryE.N. HughesM.M. KimballA. DeSistoC.L. KenemerB. ShamoutM. GarciaM.C. Reagan-SteinerS. PetersenE.E. KoumansE.H. RitcheyM.D. KingB.A. JonesC.M. BrissP.A. DelaneyL. PatelA. PolenK.D. SivesK. Meaney-DelmanD. Chatham-StephensK. Lung Injury Response Epidemiology / Surveillance Grou; Lung Injury Response Epidemiology / Surveillance Task Force Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injuries – United States, October 2019 MMWR Morb. Mortal. Wkly. Rep. 68 2019 985 989 10.15585/mmwr.mm6843e1 Erratum in: MMWR Morb. Mortal. Wkly. Rep. 68 (2019) 1170. DOI: 10.15585/mmwr.mm6850a6 Open DOISearch in Google Scholar

3 Lampi, A.-M.: Analysis of Tocopherols and Tocotrienols by HPLC; AOAC Lipid library. Available at: https://lipidlibrary.aocs.org/lipid-analysis/selected-topics-in-the-analysis-of-lipids/analysis-of-tocopherols-and-tocotrienols-by-hplc (accessed March, 2021) LampiA.-M. Analysis of Tocopherols and Tocotrienols by HPLC AOAC Lipid library Available at: https://lipidlibrary.aocs.org/lipid-analysis/selected-topics-in-the-analysis-of-lipids/analysis-of-tocopherols-and-tocotrienols-by-hplc (accessed March, 2021) Search in Google Scholar

4 Eitenmiller, R.R. and J. Lee: Vitamin E: Food Chemistry, Composition, and Analysis; CRC Press, New York, NY, USA, 2004. ISBN: 0203970144, 9780203970140 EitenmillerR.R. LeeJ. Vitamin E: Food Chemistry, Composition, and Analysis CRC Press New York, NY, USA 2004 ISBN: 0203970144, 9780203970140 10.1201/9780203970140 Search in Google Scholar

5 Ng, M.H. and C.Y. May: Chromatographic Analysis of Tocopherols and Tocotrienols in Palm Oil; J. Chrom. Sci. 50 (2012) 283–286. DOI: 10.1093/chromsci/bms002 NgM.H. MayC.Y. Chromatographic Analysis of Tocopherols and Tocotrienols in Palm Oil J. Chrom. Sci. 50 2012 283 286 10.1093/chromsci/bms002 Open DOISearch in Google Scholar

6 Mayne, S.T. and R.S. Parker: HPLC Analysis of Vitamin E by Conversion to α-Tocopheryl Acetate in Samples Containing Canthaxanthin or Other Coeluting Compounds; J. Agric. Food Chem. 36 (1988) 483–485. DOI: 10.1021/jf00081a019 MayneS.T. ParkerR.S. HPLC Analysis of Vitamin E by Conversion to α-Tocopheryl Acetate in Samples Containing Canthaxanthin or Other Coeluting Compounds J. Agric. Food Chem. 36 1988 483 485 10.1021/jf00081a019 Open DOISearch in Google Scholar

7 Moldoveanu, S.C.: Profiling of Lipids from Fruit and Seed Extracts; in Sea Food, Marine Based Dietary Supplement, Fruit and Seed, edited by Su Chen, Chapter 5, 1–19, Lipidomics, Transworld Research, Kerala, India (2012). ISBN: 978-81-7895-573-5 MoldoveanuS.C. Profiling of Lipids from Fruit and Seed Extracts in Sea Food, Marine Based Dietary Supplement, Fruit and Seed, edited by Su Chen, Chapter 5, 1–19 Lipidomics, Transworld Research Kerala, India 2012 ISBN: 978-81-7895-573-5 Search in Google Scholar

8 Rupérez, F.J., D. Martín, E. Herrera, and C. Barbas: Chromatographic Analyses of Alpha-Tocopherol and Related Compounds in Various Matrices; J. Chromatogr. A 935 (2001) 45–69. DOI: 10.1016/s0021-9673(01)01101-3 RupérezF.J. MartínD. HerreraE. BarbasC. Chromatographic Analyses of Alpha-Tocopherol and Related Compounds in Various Matrices J. Chromatogr. A 935 2001 45 69 10.1016/s0021-9673(01)01101-3 Open DOISearch in Google Scholar

9 Xu, Z.: Analysis of Tocopherols and Tocotrienols; Current Protocols in Food Analytical Chemistry 4 (2002) D1.5.1–D1.5.12. DOI: 10.1002/0471142913.fad0105s04 XuZ. Analysis of Tocopherols and Tocotrienols Current Protocols in Food Analytical Chemistry 4 2002 D1.5.1 D1.5.12 10.1002/0471142913.fad0105s04 Open DOISearch in Google Scholar

10 Gentili, A. and F. Caretti: Evaluation of a Method Based on Liquid Chromatography-Diode Array Detector-Tandem Mass Spectrometry for a Rapid and Comprehensive Characterization of the Fat-Soluble Vitamin and Carotenoid Profile of Selected Plant Foods; J. Chromatogr. A 1218 (2011) 684–697. DOI: 10.1016/j.chroma.2010.12.001 GentiliA. CarettiF. Evaluation of a Method Based on Liquid Chromatography-Diode Array Detector-Tandem Mass Spectrometry for a Rapid and Comprehensive Characterization of the Fat-Soluble Vitamin and Carotenoid Profile of Selected Plant Foods J. Chromatogr. A 1218 2011 684 697 10.1016/j.chroma.2010.12.001 21190690 Open DOISearch in Google Scholar

11 Hryniewicka, M., A. Karpinska, M. Kijewska, M.J. Turkowicz, and J. Karpinska: LC/MS/MS Analysis of α-Tocopherol and Coenzyme Q₁₀ Content in Lyophilized Royal Jelly, Beebread and Drone Homogenate; J. Mass Spectrom. 51 (2016) 1023–1029. DOI: 10.1002/jms.3821. HryniewickaM. KarpinskaA. KijewskaM. TurkowiczM.J. KarpinskaJ. LC/MS/MS Analysis of α-Tocopherol and Coenzyme Q₁₀ Content in Lyophilized Royal Jelly, Beebread and Drone Homogenate J. Mass Spectrom. 51 2016 1023 1029 10.1002/jms.3821 27459546 Open DOISearch in Google Scholar

12 Jiang, Q., T. Xu, J. Huang, A.S. Jannasch, B. Cooper, and C. Yang: Analysis of Vitamin E Metabolites Including Carboxychromanols and Sulfated Derivatives Using LC/MS/MS; J. Lipid Res. 56 (2015) 2217–2225. DOI: 10.1194/jlr.d061663 JiangQ. XuT. HuangJ. JannaschA.S. CooperB. YangC. Analysis of Vitamin E Metabolites Including Carboxychromanols and Sulfated Derivatives Using LC/MS/MS J. Lipid Res. 56 2015 2217 2225 10.1194/jlr.d061663 461740826351363 Open DOISearch in Google Scholar

13 Zhou, W.: Alpha-Tocopherol Analysis by HPLC; Protocol Exchange Method Article Biochemistry (2011). Available at: https://assets.researchsquare.com/files/nprot-2154/v1/manuscript.pdf (assecced March 2021) DOI: 10.1038/protex.2011.244 ZhouW. Alpha-Tocopherol Analysis by HPLC Protocol Exchange Method Article Biochemistry 2011 Available at: https://assets.researchsquare.com/files/nprot-2154/v1/manuscript.pdf (assecced March 2021) 10.1038/protex.2011.244 Open DOISearch in Google Scholar

14 Arora, R., S. Kaul, P. Winkler, and P. Taylor: Analysis of Vitamin E and Vitamin E Acetate in Vape Oils; SCIEX, Application Note, 2019, Doc. No. RUO-MKT-02-10498-A. Available at: https://sciex.com/content/dam/SCIEX/pdf/tech-notes/all/Analysis-of-Vitamin-E-and-Vitamin-E-Acetate-in-Vape-Oils.pdf (accessed March, 2021) AroraR. KaulS. WinklerP. TaylorP. Analysis of Vitamin E and Vitamin E Acetate in Vape Oils SCIEX, Application Note 2019 Doc. No. RUO-MKT-02-10498-A. Available at: https://sciex.com/content/dam/SCIEX/pdf/tech-notes/all/Analysis-of-Vitamin-E-and-Vitamin-E-Acetate-in-Vape-Oils.pdf (accessed March, 2021) Search in Google Scholar

15 Rodriguez-Lafuente, A. and P. Joza: Determination of α-Tocopherol Acetate (Vitamin E Acetate) in E-Liquids and Cannabis Liquids Samples – A Comparison between HPLC-DAD and LC-MS/MS Methods: CORESTA Congress 2020, Oct.12–Nov.12, STPOST 08 (1815). Available at: https://www.coresta.org/sites/default/files/events/CORESTA2020_Programme_web_201012.pdf (accessed March, 2021) Rodriguez-LafuenteA. JozaP. Determination of α-Tocopherol Acetate (Vitamin E Acetate) in E-Liquids and Cannabis Liquids Samples – A Comparison between HPLC-DAD and LC-MS/MS Methods: CORESTA Congress 2020, Oct.12–Nov.12, STPOST 08 (1815) Available at: https://www.coresta.org/sites/default/files/events/CORESTA2020_Programme_web_201012.pdf (accessed March, 2021) Search in Google Scholar

16 Moldoveanu, S.C.: Analysis of α-Tocopherol in Tobacco and Cigarette Smoke; Beitr. Tabakforsch. Int. 29 (2020) 56–64. DOI: 10.2478/cttr-2020-0007 MoldoveanuS.C. Analysis of α-Tocopherol in Tobacco and Cigarette Smoke Beitr. Tabakforsch. Int. 29 2020 56 64 10.2478/cttr-2020-0007 Open DOISearch in Google Scholar