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Increased expression of Cardiotrophin-1 in cardiomyopathy patients

S Sharif

S Sharif

Department of Zoology, Lahore College for Women UniversityLahore, Pakistan
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Sharif, S
, 
A Saleem

A Saleem

Department of Zoology, Lahore College for Women UniversityLahore, Pakistan
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Saleem, A
, 
S Naz

S Naz

Department of Zoology, Lahore College for Women UniversityLahore, Pakistan
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Naz, S
, 
F Rashid

F Rashid

Department of Zoology, Lahore College for Women UniversityLahore, Pakistan
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Rashid, F
, 
M Iqtedar

M Iqtedar

Department of Biotechnology, Lahore College for Women UniversityLahore, Pakistan
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Iqtedar, M
, 
A Kaleem

A Kaleem

Department of Biotechnology, Lahore College for Women UniversityLahore, Pakistan
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Kaleem, A
 and 
A Latif

A Latif

Department of Zoology, Lahore College for Women UniversityLahore, Pakistan
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Latif, A
  
Jul 27, 2021
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Article Category: Original Article
Published Online: Jul 27, 2021
Page range: 21 - 26
DOI: https://doi.org/10.2478/bjmg-2021-0008
Keywords
© 2021 Sharif S, Saleem A, Naz S, Rashid F, Iqtedar M, Kaleem A, Latif A, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Cardiotrophin-1 gene expression in the control and CM groups.
Cardiotrophin-1 gene expression in the control and CM groups.

Figure 2

Scattered plot showing correlation between CT-1 gene and BMI in CM group.
Scattered plot showing correlation between CT-1 gene and BMI in CM group.

Demographic parameters of the cardiomyopathy and control groups_

Parameters CM Group (n=20) Control Group (n=20)
Age (years) 40.10±6.03 35.00±3.71
BMI (kg/m2) 25.11±0.39 24.22±0.66
SBP (mmHg) 124.0±0.7 103.0±0.9
DBP (mmHg) 83.0±0.8 79.0±1.5
CT-1 (arbitrary units) 5.29±0.34 1.00

Prevalence of physical activity, etiological attributes and symptomatology in the cardiomyopathy group_

Variables CM Group (n=40)
Physical activity (%)
vigorous 5.0
moderate 20.0
sedentary 75.0
Etiological attributes (%)
idiopathic 65.0
nutritional 15.0
multifactorial 15.0
Symptomatology (%)
breathless 85.0
palpitations 75.0
chest pain 45.0

Correlation between the cardiotrophin-1 gene and demographic parameters in cardiomyopathy group_

Parameters r Values p Values
Age (years) 0.54a <0.05
BMI (kg/m2) 0.46b <0.01
SBP (mmHg) –0.079 >0.05
DBP (mmHg) 0.069 >0.05
Language:
English
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Journal Subjects:
Medicine, Basic Medical Science, Basic Medical Science, other
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