<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The post-weaning period is very stressful for piglets, leading to a transitory inflammation, alterations in the intestinal barrier, oxidative stress and a higher susceptibility to intestinal diseases with economic losses. The finding of new nutritional alternatives with anti-inflammatory, anti-bacterial, anti-oxidant properties is a challenge in post-weaning piglet’s nutrition. Of these strategies, those based on agro-industry wastes rich in bioactive compounds are promising, the increasing number of studies focusing on the use of these wastes as successful modulators of post-weaning – associated disturbances in piglets. This review describes the role of grape by-products in the modulation of inflammation, reinforcement of the intestinal barrier and their role as antioxidant factors. Also, their in-depth intracellular mechanisms of action related to their anti-inflammatory, antioxidant properties are described.</p>
</abstract>

The post-weaning period is very stressful for piglets, leading to a transitory inflammation, alterations in the intestinal barrier, oxidative stress and a higher susceptibility to intestinal diseases with economic losses. The finding of new nutritional alternatives with anti-inflammatory, anti-bacterial, anti-oxidant properties is a challenge in post-weaning piglet’s nutrition. Of these strategies, those based on agro-industry wastes rich in bioactive compounds are promising, the increasing number of studies focusing on the use of these wastes as successful modulators of post-weaning – associated disturbances in piglets. This review describes the role of grape by-products in the modulation of inflammation, reinforcement of the intestinal barrier and their role as antioxidant factors. Also, their in-depth intracellular mechanisms of action related to their anti-inflammatory, antioxidant properties are described.

Grape by-products and their efficiency in alleviating the intestinal disorders in post-weaning piglets

Laboratory of Animal Biology, INCDBNA-IBNA

Archiva Zootechnica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

The post-weaning period is very stressful for piglets, leading to a transitory inflammation, alterations in the intestinal barrier, oxidative stress and a...

Grape by-products and their efficiency in alleviating the intestinal disorders in post-weaning piglets

Published Online: May 27, 2023

Page range: 56 - 76

DOI: https://doi.org/10.2478/azibna-2023-0004

Keywords
grape by-products, post-weaning, pigs, intestine, inflammation, oxidative stress, signalling pathways

© 2023 Gina Cecilia Pistol et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Grape by-products and their efficiency in alleviating the intestinal disorders in post-weaning piglets

Published Online: May 27, 2023

Page range: 56 - 76

DOI: https://doi.org/10.2478/azibna-2023-0004

Keywordsgrape by-products, post-weaning, pigs, intestine, inflammation, oxidative stress, signalling pathways

© 2023 Gina Cecilia Pistol et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
grape by-products, post-weaning, pigs, intestine, inflammation, oxidative stress, signalling pathways