<abstract xmlns="http://www.w3.org/1999/xhtml"><p>We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.</p></abstract>

We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.

A Polarized Light Microscopy Study in a Case of Morphea

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"A Polarized Light Microscopy Study in a Case of Morphea"}

We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of...

A Polarized Light Microscopy Study in a Case of Morphea

Published Online: Apr 22, 2021

Page range: 1 - 4

DOI: https://doi.org/10.2478/arsm-2020-0001

Keywords
morphea, polarized microscopy, picro sirius red, collagen

© 2020 Mocanu Liliana et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

A Polarized Light Microscopy Study in a Case of Morphea

Published Online: Apr 22, 2021

Page range: 1 - 4

DOI: https://doi.org/10.2478/arsm-2020-0001

Keywordsmorphea, polarized microscopy, picro sirius red, collagen

© 2020 Mocanu Liliana et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
morphea, polarized microscopy, picro sirius red, collagen