1. bookVolume 26 (2020): Issue 1 (February 2020)
Journal Details
License
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Journal
First Published
16 Feb 2013
Publication timeframe
4 times per year
Languages
English
access type Open Access

A Polarized Light Microscopy Study in a Case of Morphea

Published Online: 22 Apr 2021
Page range: 1 - 4
Journal Details
License
Format
Journal
First Published
16 Feb 2013
Publication timeframe
4 times per year
Languages
English
Abstract

We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.

Keywords

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