1. bookVolume 14 (2014): Issue 3 (July 2014)
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Journal
eISSN
2300-8733
First Published
25 Nov 2011
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4 times per year
Languages
English
access type Open Access

A Review on Effects of Aloe Vera as a Feed Additive in Broiler Chicken Diets

Published Online: 29 Jul 2014
Volume & Issue: Volume 14 (2014) - Issue 3 (July 2014)
Page range: 491 - 500
Received: 16 Oct 2013
Accepted: 03 Jan 2014
Journal Details
License
Format
Journal
eISSN
2300-8733
First Published
25 Nov 2011
Publication timeframe
4 times per year
Languages
English
Abstract

Prohibition of application of antibiotic growth promoters in broiler chicken diets has resulted in increased use of herbs as natural additives in broiler feeds over the recent years. Researchers particularly look for herbs that can affect such parameters as growth performance, immune response, or treatment of certain diseases. Aloe vera is a well-known herb characterized by properties such as anti-bacterial, anti-viral, anti-fungal, anti-tumor, anti-inflammatory, immunomodulatory, wound-healing, anti-oxidant, and anti-diabetic effects. During the past years, attention has shifted toward Aloe vera as a natural additive to broiler diets, and studies have shown that Aloe vera can improve immune response and growth performance in broilers. In addition, Aloe vera is an excellent alternative for antibiotic growth promoters and anticoccidial drugs. Since Aloe vera can be used for broilers in the form of gel, powder, ethanolic extract, aqueous extract, and a polysaccharide contained in Aloe vera gel (i.e. acemannan), more studies are required to determine the best form and to compare Aloe vera with other medicinal herbs. This paper reviews effects of Aloe vera on intestinal microflora, growth performance, immune response, and coccidiosis in broiler chickens.

Keywords

Agarry O.O., Olaleye M.T., Bello - Michael C.O. (2005). Comparative antimicrobial activities of Aloe vera gel and leaf. Afr. J. Biotechnol., 4: 1413–1414.Search in Google Scholar

Ahlawat K.S., Khatkar B.S. (2011). Processing, food applications and safety of Aloe vera products: a review. J. Food Sci. Technol., 48: 525–533.Search in Google Scholar

Akhtar M., Hai A., Awais M.M., Iqbal Z., Muhammad F., Anwar M.I. (2012). Immunostimulatory and protective effects of Aloe vera against coccidiosis in industrial broiler chickens. Vet. Parasitol., 186: 170–177.Search in Google Scholar

Alemdar S., Agaoglu S. (2009). Investigation of in vitro antimicrobial activity of Aloe vera juice. J. Anim. Vet. Adv., 8: 99–102.Search in Google Scholar

Alemi F., Mahdavi A., Ghazvinian K., Ghaderi M., Darabighane B. (2012). The effects of different levels of Aloe vera gel powder on antibody titer against Newcastle disease virus and performance in broilers. Proc. International Poultry Scientific Forum, Georgia World Congress Center, Atlanta, Georgia, 23–24.01.2012, p. 47.Search in Google Scholar

Altuğ N., Yüksek N., Ağaoğlu Z.T. (2010). Immunostimulatory effects of Aloe vera and β-Glucan on cellular and humoral immune responses following vaccination with polyvalent vaccines in dogs. J. Fac. Vet. Med., University of Kafkas, Kars, 16: 405–412.Search in Google Scholar

Besharatian M., Arshami J., Valizade R., Tahmasebi A., BahariKashani R. (2012). Effects of Aloe vera leaf powder and extract on immune response in broilers. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 366–370.Search in Google Scholar

Boudreau M.D., Beland F.A. (2006). An evaluation of the biological and toxicological properties of Aloe barbadensis (Miller), Aloe vera. J. Environ. Sci. Heal. C., 24: 103–154.Search in Google Scholar

Chinnah A.D., Baig M.A., Tizard I.R., Kemp M.C. (1992). Antigen dependent adjuvant activity of a polydispersed beta-(1, 4)-linked acetylated mannan (acemannan). Vaccine, 10: 551–557.Search in Google Scholar

Choi S., Chung M.-H. (2003). A review on the relationship between Aloe vera components and their biologic effects. Semin. Integr. Med., 1: 53–62.Search in Google Scholar

Christaki E.V., Florou - Paneri P.C. (2010). Aloe vera: A plant for many uses. J. Food Agric. Environ., 8: 245–249.Search in Google Scholar

Dai B., Jiang L., Chen S. (2007). Effects of medicinal herb and polysaccharide from Aloe on gut microflora, immune function and growth performance in broiler. China Poultry., 29: 21–24.Search in Google Scholar

Darabighane B., Zarei A. (2011). The effects of the different levels of Aloe vera gel on oocysts shedding in broilers with coccidiosis. Planta Med., 77: PN2.Search in Google Scholar

Darabighane B., Zarei A., Zare Shahneh A., Mahdavi A. (2011 a). A study on the effects of Aloe vera gel on phagocytic ability of macrophages and blood parameters in broilers. Poultry Sci., 90 (E-Suppl. 1): p. 128.Search in Google Scholar

Darabighane B., Zarei A., Zare Shahneh A., Mahdavi A. (2011 b). Effects of different levels of Aloe vera gel as an alternative to antibiotic on performance and ileum morphology in broilers. Ital. J. Anim. Sci., 10: 189–194.10.4081/ijas.2011.e36Search in Google Scholar

Darabighane B., Zarei A., Shahneh A.Z. (2012). The effects of different levels of Aloe vera gel on ileum microflora population and immune response in broilers: a comparison to antibiotic effects. J. Appl. Anim. Res., 40: 31–36.Search in Google Scholar

Djeraba A., Quere P. (2000). In vivo macrophage activation in chickens with Acemannan, a complex carbohydrate extracted from Aloe vera. Int. J. Immunopharmaco., 22: 365–372.Search in Google Scholar

Eshun K., He Q. (2004). Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries. a review. Crit. Rev. Food Sci., 44: 91–96.Search in Google Scholar

Femenia A., Sanchez E.S., Simal S., Rossello C. (1999). Compositional features of polysaccharides from Aloe vera (Aloe barbadensis Miller) plant tissues. Carbohyd. Polym., 39: 109–117.Search in Google Scholar

Feng Y.Z., Gu F.X., Yuan Z.X., Zhang Y.J., Liu S.H., Hu L.L., Xu L. (2011). Effects of Aloe polysaccharide on immune organ index and immune efficacy of vaccine against Newcastle disease in broiler. J. Henan Agricult. Univ., 45: 432–436.Search in Google Scholar

Guo F., Williams B., Kwakkel R., Verstegen M. (2003). In vitro fermentation characteristics of two mushroom species, an herb, and their polysaccharide fractions, using chicken cecal contents as inoculum. Poultry Sci., 82: 1608–1615.Search in Google Scholar

Guo F., Kwakkel R., Williams B., Parmentier H., Li W., Yang Z., Verstegen M. (2004 a). Effects of mushroom and herb polysaccharides on cellular and humoral immune responses of Eimeria tenella-infected chickens. Poultry Sci., 83: 1124–1132.10.1093/ps/83.7.112415285503Search in Google Scholar

Guo F.C., Williams B.A., Kwakkel R.P., Li H.S., Li X.P., Luo J.Y., Li W.K., Verstegen M.W.A. (2004 b). Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poultry Sci., 83: 175–182.10.1093/ps/83.2.17514979567Search in Google Scholar

Hamman J.H. (2008). Composition and applications of Aloe vera leaf gel. Molecules., 13: 1599–1616.Search in Google Scholar

Hardy B. (2002). The issue of antibiotic use in the livestock industry: what have we learned? Anim. Biotechnol., 13: 129–147.Search in Google Scholar

Harlev E., Nevo E., Lansky E.P., Ofir R., Bishayee A. (2012). Anticancer potential of Aloes: antioxidant, antiproliferative, and immunostimulatory attributes. Planta Med., 78: 843–852.Search in Google Scholar

Hassanbeigy - Lakeh Z., Roustaee Ali - Mehr M., Haghighian - Roudsari M. (2012). Effect of Aloe gel on broiler performance. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 973–977.Search in Google Scholar

He C.L., Fu B.D., Shen H.Q., Jiang X.L., Wei X.B. (2011). Fumaric acid, an antibacterial component of Aloe vera L. Afr. J. Biotechnol., 10: 2973–2977.Search in Google Scholar

Jiang L., Feng Y., Yang X., Zhou X., Yang D. (2005). Effects of gel, polysaccharide and acemannan from Aloe vera on broiler gut flora, microvilli density, immune function and growth performance. Chinese J. Vet. Sci., 25: 668–671.Search in Google Scholar

Karaca K., Sharma J.M., Nordgren R. (1995). Nitric oxide production by chicken macrophages activated by Acemannan, a complex carbohydrate extracted from Aloe vera. Int. J. Immunopharmaco., 17: 183–188.Search in Google Scholar

Kwon K.H., Hong M.K., Hwang S.Y., Moon B.Y., Shin S., Baek J.H., Park Y.H. (2011). Antimicrobial and immunomodulatory effects of Aloe vera peel extract. J. Med. Plants Res., 5: 5384–5392.Search in Google Scholar

Mahdavi A., Alemi F., Ghazvinian K., Ghaderi M., Darabighane B. (2012). Study of effects of different levels of Aloe vera gel powder on antibody titre against sheep red blood cells and other blood parameters in broilers. Abstracts 2012, British Poultry Abstracts, 8: 49–50.Search in Google Scholar

Mbanga J., Mangoma N., Saidi B. (2010). An evaluation of the antimicrobial activities of Aloe barbadensis, A. chabaudii and A. arborescens leaf extracts used in folklore veterinary medicine in Zimbabwe. J. Anim. Vet. Adv., 9: 2918–2923.Search in Google Scholar

McAnalley B.H. (1989). Process for preparation of aloe products, Google Patents.Search in Google Scholar

Mehala C., Moorthy M. (2008). Effect of Aloe vera and Curcuma longa (turmeric) on carcass characteristics and biochemical parameters of broilers. Int. J. Poultry Sci., 7: 857–861.Search in Google Scholar

Mmereole F. (2011). Evaluation of the dietary inclusion of Aloe vera as an alternative to antibiotic growth promoter in broiler production. Pakistan J. Nutr., 10: 1–5.Search in Google Scholar

Mwale M., Bhebhe E., Chimonyo M., Halimani T.E. (2005). Use of herbal plants in poultry health management in the Mushagashe small-scale commercial farming area in Zimbabwe. Int. J. Appl. Res. Vet. M., 3: 163–170.Search in Google Scholar

Mwale M., Bhebhe E., Chimonyo M., Halimani T. (2006). The in vitro studies on the effect of Aloe vera ((L.) Webb. and Berth.) and Aloe spicata (L. f.) on the control of coccidiosis in chickens. Int. J. Appl. Res. Vet. M., 4: 128–133.Search in Google Scholar

Olupona J.A., Omotoso O.R., Adeyeye A.A., Kolawole O.D., Airemionkhale A.P., Adejinmi O.O. (2010). Effect of aloe vera juice application through drinking water on performance, carcass characteristics, hematology and organoleptics properties in broilers. Poultry Sci., 88 (E-Suppl. 1): p. 42.Search in Google Scholar

Pandey R., Mishra A. (2010). Antibacterial activities of crude extract of Aloe barbadensis to clinically isolated bacterial pathogens. Appl. Biochem. Biotech., 160: 1356–1361.Search in Google Scholar

Shokraneh M., Ghalamkari Gh., Toghyani M., Tabeidian S.A., Taghizadeh M., Landy N., Fekri F. (2012). Effect of Aloe vera (Aloe barbadensis Miller) gel in drinking water on some of the immune responses in broiler chickens. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 791–795.Search in Google Scholar

Sinurat A.P., Purwadaria T., Togatorop M.H., Pasaribu T., Bintang I.A.K., Sitompul S., Rosida J. (2002). Responses of broilers to Aloe vera bioactives as feed additive: the effect of different forms and levels of bioactives on performances of broilers. Jurnal Ilmu Ternak dan Veteriner, 7: 69–75.Search in Google Scholar

Sun Z., Wei K., Yan Z., Zhu X., Wang X., Wang H., Tan Y., Sheng P., Zhu R. (2011). Effect of immunological enhancement of aloe polysaccharide on chickens immunized with Bordetella avium inactivated vaccine. Carbohyd. Polym., 86: 684–690.Search in Google Scholar

Tizard I.R., Ni Y. (1998). Carbohydrates, immune stimulating. In: Encyclopedia of immunology, Delves P.J., Roitt I.M. (eds). Academic Press Inc., San Diego, CA, 2nd ed., pp. 427–431.10.1006/rwei.1999.0110Search in Google Scholar

Valle - Paraso M., Vidamo P., Anunciado R., Lapitan A. (2005). Effects of Aloe vera (Aloe barbadensis) on the white blood cell count and antibody titre of broiler chickens vaccinated against Newcastle disease. Philipp. J. Vet. Med., 42: 49–52.Search in Google Scholar

Verstegen M.W., Williams B.A. (2002). Alternatives to the use of antibiotics as growth promoters for monogastric animals. Anim. Biotechnol., 13: 113–127.Search in Google Scholar

Waihenya R., Mtambo M., Nkwengulila G. (2002). Evaluation of the efficacy of the crude extract of Aloe secundiflora in chickens experimentally infected with Newcastle disease virus. J. Ethnopharmacol., 79: 299–304.Search in Google Scholar

Yang Y., Iji P., Choct M. (2009). Dietary modulation of gut microflora in broiler chickens: a review of the role of six kinds of alternatives to in-feed antibiotics. World Poultry Sci. J., 65: 97–114.Search in Google Scholar

Yim D., Kang S.S., Kim D.W., Kim S.H., Lillehoj H.S., Min W. (2011). Protective effects of Aloe vera-based diets in Eimeria maxima-infected broiler chickens. Exp. Parasitol., 127: 322–325.Search in Google Scholar

Zhang L., Tizard I.R. (1996). Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera gel. Immunopharmacology, 35: 119–128.Search in Google Scholar

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