<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Aim</bold>: The present study aims to evaluate the efficacy of naturally-derived bovine hydroxyapatite (Cerabone) versus demineralized freeze-dried bone allograft both combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects.
<bold>Method</bold>: This clinical study included 20 systemically healthy patients, with grade II mandibular furcation defects, performed over 6 months. Control group comprised of open flap debridement + demineralized freeze-dried bone allograft + platelet-rich fibrin and test group comprised of open flap debridement + Cerabone + platelet-rich fibrin. Clinical parameters included: Plaque index, Modified Sulcular bleeding index, Vertical probing pocket depth, Horizontal probing depth, Probing clinical attachment level, Radiographic furcation depth, and radiographic bone fill percentage.
<bold>Results</bold>: Both groups showed satisfactory bone regeneration and improvement in clinical parameters. The test group exhibited greater reduction in vertical probing pocket depth, horizontal probing depth, and higher radiographic bone fill percentage when compared to control group, although these findings were not statistically significant.
<bold>Conclusion</bold>: Both bone grafts were equally effective in treatment of grade II furcation defects. Further long-term studies are required to explore their maximum regenerative potential.
</abstract>

Aim: The present study aims to evaluate the efficacy of naturally-derived bovine hydroxyapatite (Cerabone) versus demineralized freeze-dried bone allograft both combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects.
Method: This clinical study included 20 systemically healthy patients, with grade II mandibular furcation defects, performed over 6 months. Control group comprised of open flap debridement + demineralized freeze-dried bone allograft + platelet-rich fibrin and test group comprised of open flap debridement + Cerabone + platelet-rich fibrin. Clinical parameters included: Plaque index, Modified Sulcular bleeding index, Vertical probing pocket depth, Horizontal probing depth, Probing clinical attachment level, Radiographic furcation depth, and radiographic bone fill percentage.
Results: Both groups showed satisfactory bone regeneration and improvement in clinical parameters. The test group exhibited greater reduction in vertical probing pocket depth, horizontal probing depth, and higher radiographic bone fill percentage when compared to control group, although these findings were not statistically significant.
Conclusion: Both bone grafts were equally effective in treatment of grade II furcation defects. Further long-term studies are required to explore their maximum regenerative potential.

Comparative clinical evaluation of xenograft (Cerabone) versus allograft combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

Aim: The present study aims to evaluate the efficacy of naturally-derived bovine hydroxyapatite (Cerabone) versus demineralized freeze-dried bone allograft...

Comparative clinical evaluation of xenograft (Cerabone) versus allograft combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects

Published Online: Jun 30, 2023

Page range: 113 - 120

Received: Jan 12, 2023

Accepted: Apr 05, 2023

DOI: https://doi.org/10.2478/amma-2023-0016

Keywords
periodontal regeneration, demineralized freeze-dried bone allograft, naturally derived bovine hydroxyapatite, furcation defects, platelet rich fibrin

© 2023 Suhina Mitra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Comparative clinical evaluation of xenograft (Cerabone) versus allograft combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects

Published Online: Jun 30, 2023

Page range: 113 - 120

Received: Jan 12, 2023

Accepted: Apr 05, 2023

DOI: https://doi.org/10.2478/amma-2023-0016

Keywordsperiodontal regeneration, demineralized freeze-dried bone allograft, naturally derived bovine hydroxyapatite, furcation defects, platelet rich fibrin

© 2023 Suhina Mitra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
periodontal regeneration, demineralized freeze-dried bone allograft, naturally derived bovine hydroxyapatite, furcation defects, platelet rich fibrin