Parameter Identification and Estimation For Stage–Structured Population Models

A stage-structured population model with unknown parameters is considered. Our purpose is to study the identifiability of the model and to develop a parameter estimation procedure. First, we analyze whether the parameter vector can or cannot uniquely be determined with the knowledge of the input-output behavior of the model. Second, we analyze how the information in the experimental data is translated into the parameters of the model. Furthermore, we propose a process to improve the recursive values of the parameters when successive observation data are considered. The structure of the state matrix leads to an analysis of the inverse of a sum of rank-one matrices.