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Influence of Perfluorodecalin Content on the Properties of Blood Substitute

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Dec 31, 2024

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Alexy T, Detterich J, Connes P, Toth K, Nader E, Kenyeres P, et al. Physical Properties of Blood and their Relationship to Clinical Conditions. Front Physiol [Internet]. 2022; 13. Available from: https://www.frontiersin.org/articles/10.3389/fphys.2022.906768/fullSearch in Google Scholar

Yuyen T. Composition of Blood. In: Transfusion Practice in Clinical Neurosciences. 2022.Search in Google Scholar

Pretini V, Koenen MH, Kaestner L, Fens MHAM, Schiffelers RM, Bartels M, et al. Red blood cells: Chasing interactions. Frontiers in Physiology. 2019.Search in Google Scholar

Stevens GA, Paciorek CJ, Flores-Urrutia MC, Borghi E, Namaste S, Wirth JP, et al. National, regional, and global estimates of anaemia by severity in women and children for 2000–19: a pooled analysis of population-representative data. Lancet Glob Health. 2022;10(5).Search in Google Scholar

Lattimore S, Wickenden C, Brailsford SR. Blood donors in England and North Wales: Demography and patterns of donation. Transfusion (Paris). 2015; 55(1).Search in Google Scholar

Jägers J, Wrobeln A, Ferenz KB. Perfluorocarbon-based oxygen carriers: from physics to physiology. Pflugers Archiv European Journal of Physiology. 2021.Search in Google Scholar

Spahn DR, Casutt M. Eliminating blood transfusions: New aspects and perspectives. Anesthesiology. 2000.Search in Google Scholar

Grzegorzewski W, Mil E, Gołda K, Czerniecka-Kubicka A, Puchała Ł. Progress in the search for blood substitutes, part 1. Preparations currently used in haemotherapy as an indicator of new drug development. Farm Pol. 2022;78(8).Search in Google Scholar

Jahr JS. Blood substitutes: Basic science, translational studies and clinical trials. Front Med Technol [Internet]. 2022; 4. Available from: https://www.frontiersin.org/articles/10.3389/fmedt.2022.989829/fullSearch in Google Scholar

Charbe NB, Castillo F, Tambuwala MM, Prasher P, Chellappan DK, Carreño A, et al. A new era in oxygen therapeutics? From perfluoro-carbon systems to haemoglobin-based oxygen carriers. Blood Rev [Internet]. 2022; 54:100927. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0268960X22000017Search in Google Scholar

Krafft MP, Riess JG. Therapeutic oxygen delivery by perfluorocarbon-based colloids. Adv Colloid Interface Sci [Internet]. 2021; 294:102407. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0001868621000488Search in Google Scholar

Ferenz KB, Steinbicker AU. Artificial oxygen carriers—past, present, and future—a review of the most innovative and clinically relevant concepts. Journal of Pharmacology and Experimental Therapeutics. 2019.Search in Google Scholar

Amberson WR, Mulder AG, Steggerda FR, Flexner J, Pankratz DS. Mammalian Life Without Red Blood Corpuscles. Science (1979) [Internet]. 1933; 78(2014):106–7. Available from: https://www.science.org/doi/10.1126/science.78.2014.106Search in Google Scholar

Gould SA, Moss GS. Clinical Development of Human Polymerized Hemoglobin as a Blood Substitute. World J Surg [Internet]. 1996; 20(9):1200–7. Available from: https://onlinelibrary.wiley.com/doi/10.1007/s002689900183Search in Google Scholar

Mohanto N, Park Y-J, Jee J-P. Current perspectives of artificial oxygen carriers as red blood cell substitutes: a review of old to cutting-edge technologies using in vitro and in vivo assessments. J Pharm Investig [Internet]. 2023; 53(1):153–90. Available from: https://link.springer.com/10.1007/s40005-022-00590-ySearch in Google Scholar

Wrobeln A, Laudien J, Groß-Heitfeld C, Linders J, Mayer C, Wilde B, et al. Albumin-derived perfluorocarbon-based artificial oxygen carriers: A physico-chemical characterization and first in vivo evaluation of bio-compatibility. European Journal of Pharmaceutics and Biopharmaceutics [Internet]. 2017; 115:52–64. Available from: https://linking-hub.elsevier.com/retrieve/pii/S0939641116305173Search in Google Scholar

Jaegers J, Haferkamp S, Arnolds O, Moog D, Wrobeln A, Nocke F, et al. Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity. Langmuir. 2021.Search in Google Scholar

Bodewes SB, Leeuwen OB van, Thorne AM, Lascaris B, Ubbink R, Lisman T, et al. Oxygen Transport during Ex Situ Machine Perfusion of Donor Livers Using Red Blood Cells or Artificial Oxygen Carriers. Int J Mol Sci [Internet]. 2020; 22(1):235. Available from: https://www.mdpi.com/1422-0067/22/1/235Search in Google Scholar

Lambert E, Gorantla VS, Janjic JM. Pharmaceutical design and development of perfluorocarbon nanocolloids for oxygen delivery in regenerative medicine. Nanomedicine. 2019.Search in Google Scholar

Haldar R, Gupta D, Chitranshi S, Singh MK, Sachan S. Artificial Blood: A Futuristic Dimension of Modern Day Transfusion Sciences. Cardiovasc Hematol Agents Med Chem. 2019;17(1).Search in Google Scholar

Alayash AI. Hemoglobin-based blood substitutes and the treatment of sickle cell disease: More harm than help? Biomolecules. 2017.Search in Google Scholar

Connes P, Alexy T, Detterich J, Romana M, Hardy-Dessources MD, Ballas SK. The role of blood rheology in sickle cell disease. Blood Rev. 2016; 30(2).Search in Google Scholar

Alexy T, Detterich J, Connes P, Toth K, Nader E, Kenyeres P, et al. Physical Properties of Blood and their Relationship to Clinical Conditions. Frontiers in Physiology. 2022.Search in Google Scholar

Woodcock JP. Physical properties of blood and their influence on blood-flow measurement. Reports on Progress in Physics. 1976; 39(1).Search in Google Scholar

James SH, Kish PE, Sutton TP. Biological and Physical Properties of Human Blood. In: Principles of Bloodstain Pattern Analysis. 2021.Search in Google Scholar

Kawthalkar S. Essentials of Haematology. Essentials of Haematology. 2013.Search in Google Scholar

Chintapalli M, Timachova K, Olson KR, Mecham SJ, Devaux D, DeS-imone JM, et al. Relationship between Conductivity, Ion Diffusion, and Transference Number in Perfluoropolyether Electrolytes. Macromolecules [Internet]. 2016; 49(9):3508–15. Available from: https://pubs.acs.org/doi/10.1021/acs.macromol.6b00412Search in Google Scholar

Yadav SS, Sikarwar BS, Ranjan P, Janardhanan R, Goyal A. Surface tension measurement of normal human blood samples by pendant drop method. J Med Eng Technol [Internet]. 2020; 44(5):227–36. Available from: https://www.tandfonline.com/doi/full/10.1080/03091902.2020.1770348Search in Google Scholar

Gersh KC, Nagaswami C, Weisel JW. Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes. Thromb Haemost. 2009;102(6).Search in Google Scholar

He D, Kim DA, Ku DN, Hu Y. Viscoporoelasticity of coagulation blood clots. Extreme Mech Lett. 2022; 56.Search in Google Scholar

Litvinov RI, Weisel JW. Blood clot contraction: Mechanisms, patho-physiology, and disease. Res Pract Thromb Haemost. 2023; 7(1).Search in Google Scholar

Pitts KL, Abu-Mallouh S, Fenech M. Contact angle study of blood dilutions on common microchip materials. J Mech Behav Biomed Mater. 2013;17.Search in Google Scholar

Wang Z, Paul S, Stein LH, Salemi A, Mitra S. Recent Developments in Blood-Compatible Superhydrophobic Surfaces. Polymers. 2022.Search in Google Scholar

Pal A, Gope A, Iannacchione G. Temperature and concentration dependence of human whole blood and protein drying droplets. Biomolecules. 2021;11(2).Search in Google Scholar

Gokhale SJ, Plawsky JL, Wayner PC. Experimental investigation of contact angle, curvature, and contact line motion in dropwise condensation and evaporation. J Colloid Interface Sci [Internet]. 2003; 259(2):354–66. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0021979702002138Search in Google Scholar

Podolean I, Fergani MEl, Candu N, Coman SM, Parvulescu VI. Selective oxidation of glucose over transitional metal oxides based magnetic core-shell nanoparticles. Catal Today [Internet]. 2023; 423:113886. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0920586122003327.Search in Google Scholar

Carter DE. Oxidation-reduction reactions of metal ions. Environ Health Perspect [Internet]. 1995; 103(suppl 1):17–9. Available from: https://ehp.niehs.nih.gov/doi/10.1289/ehp.95103s117Search in Google Scholar

Kim J-H, Jung E-A, Kim J-E. Perfluorocarbon-based artificial oxygen carriers for red blood cell substitutes: considerations and direction of technology. J Pharm Investig [Internet]. 2024; 54(3):267–82. Available from: https://link.springer.com/10.1007/s40005-024-00665-y.Search in Google Scholar

Li S, Pang K, Zhu S, Pate K, Yin J. Perfluorodecalin-based oxygenated emulsion as a topical treatment for chemical burn to the eye. Nat Commun [Internet]. 2022; 13(1):7371. Available from: https://www.nature.com/articles/s41467-022-35241-1Search in Google Scholar

Moradi S, Jahanian-Najafabadi A, Roudkenar MH. Artificial Blood Substitutes: First Steps on the Long Route to Clinical Utility. Clin Med Insights Blood Disord [Internet]. 2016; 9:CMBD.S38461. Available from: http://journals.sagepub.com/doi/10.4137/CMBD.S38461Search in Google Scholar

Habler OP, Messmer KF. Tissue perfusion and oxygenation with blood substitutes. Adv Drug Deliv Rev [Internet]. 2000; 40(3):171–84. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0169409X99000484Search in Google Scholar

Riess JG. The Design and Development of Improved Fluorocarbon-Based Products for use in Medicine and Biology. Artificial Cells, Blood Substitutes, and Biotechnology [Internet]. 1994; 22(2):215–34. http://www.tandfonline.com/doi/full/10.3109/10731199409117416.Search in Google Scholar

Kuznetsova IN. Perfluorocarbon emulsions: Stability in vitro and in vivo (A review). Pharmaceutical Chemistry Journal. 2003.Search in Google Scholar

Nader E, Skinner S, Romana M, Fort R, Lemonne N, Guillot N, et al. Blood Rheology: Key Parameters, Impact on Blood Flow, Role in Sickle Cell Disease and Effects of Exercise. Front Physiol [Internet]. 2019; 10(OCT). Available from: https://www.frontiersin.org/article/10.3389/fphys.2019.01329/fullSearch in Google Scholar

Shaik A, Chen Q, Mar P, Kim H, Mejia P, Pacheco H, et al. Blood hyperviscosity in acute and recent COVID-19 infection. Clin Hemorheol Microcirc [Internet]. 2022; 82(2):149–55. Available from: https://www.medra.org/servlet/aliasRe-solver?alias=iospress&doi=10.3233/CH-221429Search in Google Scholar

Pop GAM, Duncker DJ, Gardien M, Vranckx P, Versluis S, Hasan D, et al. The clinical significance of whole blood viscosity in (cardio)vascular medicine. Neth Heart J. 2002;10(12).Search in Google Scholar

Pal R. Rheology of concentrated suspensions of deformable elastic particles such as human erythrocytes. J Biomech [Internet]. 2003; 36(7):981–9. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0021929003000678Search in Google Scholar

Yilmaz F, Gundogdu MY. A critical review on blood flow in large arteries; relevance to blood rheology, viscosity models, and physiologic conditions. Korea Australia Rheology Journal. 2008.Search in Google Scholar

Vásquez DM, Ortiz D, Alvarez OA, Briceño JC, Cabrales P. Hemorheological implications of perfluorocarbon based oxygen carrier interaction with colloid plasma expanders and blood. Biotechnol Prog [Internet]. 2013; 29(3):796–807. Available from: https://aiche.onlinelibrary.wiley.com/doi/10.1002/btpr.1724Search in Google Scholar

Mukherji B, Sloviter HA. A stable perfluorochemical blood substitute. Transfusion (Paris) [Internet]. 1991; 31(4):324–6. Available from: https://onlinelibrary.wiley.com/doi/10.1046/j.1537-2995.1991.31491213296.xSearch in Google Scholar

Syed UT, Dias AMA, Crespo J, Brazinha C, Sousa HC de. Studies on the formation and stability of perfluorodecalin nanoemulsions by ultra-sound emulsification using novel surfactant systems. Colloids Surf A Physicochem Eng Asp [Internet]. 2021; 616:126315. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0927775721001849Search in Google Scholar