Open Access

The role of Th17 lymphocytes in the pathogenesis of chronic rhinosinusitis

, , , ,  and   
Sep 23, 2024

Cite
Download Cover

Manasterski J, Czajczyńska M. Leczenie. przewlekłego zapalenia zatok przynosowych. Hygeia Public Health. 2021; 56: 42–45. ManasterskiJ CzajczyńskaM Leczenie. przewlekłego zapalenia zatok przynosowych Hygeia Public Health 2021 56 42 45 Search in Google Scholar

Wang M, Zhang N, Zheng M, Li Y, Meng L, Ruan Y, Han J, Zhao N, Wang X, Zhang L, Bachert C. Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 2019; 144: 1254–1264. WangM ZhangN ZhengM LiY MengL RuanY HanJ ZhaoN WangX ZhangL BachertC Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps J. Allergy Clin. Immunol. 2019 144 1254 1264 Search in Google Scholar

Woś J, Remjasz A. Inflammation of the nasal mucosa and paranasal sinuses. Pol. Otorhino. Rev., 2019; 8: 16–26. WośJ RemjaszA Inflammation of the nasal mucosa and paranasal sinuses Pol. Otorhino. Rev. 2019 8 16 26 Search in Google Scholar

Cohen NA, Widelitz JS, Chiu AG, Palmer JN, Kennedy DW. Familial aggregation of sinonasal polyps correlates with severity of disease. J. Otolaryngol. Head Neck Surg., 2006; 134: 601–604. CohenNA WidelitzJS ChiuAG PalmerJN KennedyDW Familial aggregation of sinonasal polyps correlates with severity of disease J. Otolaryngol. Head Neck Surg. 2006 134 601 604 Search in Google Scholar

Jani AL, Hamilos DL. Current thinking on the relationship between rhinosinusitis and asthma. J. Asthma. 2005; 42: 1–7. JaniAL HamilosDL Current thinking on the relationship between rhinosinusitis and asthma J. Asthma. 2005 42 1 7 Search in Google Scholar

Bachert C, Pawankar R, Zhang L, Bunnag C, Fokkens WJ, Hamilos DL, Jirapongsananuruk O, Kern R, Meltzer EO, Mullol J, Naclerio R, Pilan R, Rhee CS, Suzaki H, Voegels R, Blaiss M. ICON: chronic rhinosinusitis. World Allergy Organ J. 2014; 7: 25. BachertC PawankarR ZhangL BunnagC FokkensWJ HamilosDL JirapongsananurukO KernR MeltzerEO MullolJ NaclerioR PilanR RheeCS SuzakiH VoegelsR BlaissM ICON: chronic rhinosinusitis World Allergy Organ J. 2014 7 25 Search in Google Scholar

Van Crombruggen K, Zhang N, Gevaert P, Tomassen P, Bachert C. Pathogenesis of chronic rhinosinusitis: Inflammation. J. Allergy Clin. Immunol. 2011; 128: 728–732. Van CrombruggenK ZhangN GevaertP TomassenP BachertC Pathogenesis of chronic rhinosinusitis: Inflammation J. Allergy Clin. Immunol. 2011 128 728 732 Search in Google Scholar

Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo J.H. Role of IL-17A in Chronic Rhinosinusitis with Nasal Polyp. Allergy Asthma Immunol. Res. 2020; 12: 507–522. RyuG BaeJS KimJH KimEH LyuL ChungYJ MoJ.H. Role of IL-17A in Chronic Rhinosinusitis with Nasal Polyp Allergy Asthma Immunol. Res. 2020 12 507 522 Search in Google Scholar

Promsopa C, Kansara S, Citardi M.J, Fakhri S, Porter P, Luong A. Prevalence of confirmed asthma varies in chronic rhinosinusitis subtypes. Int. Forum Allergy Rhinol. 2016; 6:373–377. PromsopaC KansaraS CitardiM.J. FakhriS PorterP LuongA Prevalence of confirmed asthma varies in chronic rhinosinusitis subtypes Int. Forum Allergy Rhinol. 2016 6 373 377 Search in Google Scholar

Hopkins C. Chronic Rhinosinusitis with Nasal Polyps. N. Engl. J. Med., 2019; 381: 55–63; HopkinsC. Chronic Rhinosinusitis with Nasal Polyps N. Engl. J. Med. 2019 381 55 63 Search in Google Scholar

Min JY, Tan BK. Risk Factors For Chronic Rhinosinusitis. Curr. Opin. Allergy Clin. Immunol. 2015; 15: 1–13. MinJY TanBK Risk Factors For Chronic Rhinosinusitis Curr. Opin. Allergy Clin. Immunol. 2015 15 1 13 Search in Google Scholar

Manciula LG, Jeican II, Tudoran LB, Albu S. Biofilms and inflammation in patients with chronic rhinosinusitis. Med Pharm Rep. 2020; 93: 374–383. ManciulaLG JeicanII TudoranLB AlbuS Biofilms and inflammation in patients with chronic rhinosinusitis Med Pharm Rep. 2020 93 374 383 Search in Google Scholar

Aggarwal S, Ghilardi N, Xie M, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem., 2003; 278: 1910–1914. AggarwalS GhilardiN XieM de SauvageFJ GurneyAL Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 J. Biol. Chem. 2003 278 1910 1914 Search in Google Scholar

Niedźwiedzka-Rystwej P, Tokarz-Deptuła B, Deptuła W. Characteristics of T lymphocyte subpopulations. Postepy Hig. Med. Dosw. 2013; 67. Niedźwiedzka-RystwejP Tokarz-DeptułaB DeptułaW Characteristics of T lymphocyte subpopulations Postepy Hig. Med. Dosw. 2013 67 Search in Google Scholar

Juszczak M, Głąbiński A. Udział limfocytów Th17 w patogenezie stwardnienia rozsianego. Postepy Hig. Med. Dosw. 2009; 63: 492–501. JuszczakM GłąbińskiA Udział limfocytów Th17 w patogenezie stwardnienia rozsianego Postepy Hig. Med. Dosw. 2009 63 492 501 Search in Google Scholar

Romagnani S. Human Th17 cells. Arthritis Res. Ther. 2008; 10: 206. RomagnaniS Human Th17 cells Arthritis Res. Ther. 2008 10 206 Search in Google Scholar

Romagnani S, Maggi E, Liotta F, Cosmi L, Annunziato F. Properties and origin of human Th17 cells. Mol. Immunol. 2009; 47: 3–7. RomagnaniS MaggiE LiottaF CosmiL AnnunziatoF Properties and origin of human Th17 cells Mol. Immunol. 2009 47 3 7 Search in Google Scholar

Szulc-Dąbrowska L, Gieryńska M, Depczyńska D, Schollenberger A, Toka FN. Limfocyty Th17 w zakażeniach bakteryjnych. Postepy Hig. Med. Dosw. 2015; 69: 398–417. Szulc-DąbrowskaL GieryńskaM DepczyńskaD SchollenbergerA TokaFN Limfocyty Th17 w zakażeniach bakteryjnych Postepy Hig. Med. Dosw. 2015 69 398 417 Search in Google Scholar

Singh SP, Zhang HH, Foley JF, Hedrick MN, Farber JM. Human T cells that are able to produce IL-17 express the chemokine receptor CCR6. J. Immunol. 2008; 180: 214–222. SinghSP ZhangHH FoleyJF HedrickMN FarberJM Human T cells that are able to produce IL-17 express the chemokine receptor CCR6 J. Immunol. 2008 180 214 222 Search in Google Scholar

Kostareva OS, Gabdulkhako AG, Kolyadenko IA, Garber MB, Tishchenko SV. Interleukin17: Functional and Structural Features, Application as a Therapeutic Target. Biochemistry. 2019; 84(Suppl 1): S193–S205. KostarevaOS GabdulkhakoAG KolyadenkoIA GarberMB TishchenkoSV Interleukin17: Functional and Structural Features, Application as a Therapeutic Target Biochemistry. 2019 84 Suppl 1 S193 S205 Search in Google Scholar

Winkler I, Gogacz M, Rechberger T. Do Th17 cells play an important role in the pathogenesis and prognosis of ovarian cancer? Ginekol. Pol. 2012; 83: 295–300. WinklerI GogaczM RechbergerT Do Th17 cells play an important role in the pathogenesis and prognosis of ovarian cancer? Ginekol. Pol. 2012 83 295 300 Search in Google Scholar

Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, Shen Y, Du J, Rubtsov YP, Rudensky AY, Ziegler SF, Littman DR. TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function. Nature. 2008; 453: 236–240. ZhouL LopesJE ChongMM IvanovII MinR VictoraGD ShenY DuJ RubtsovYP RudenskyAY ZieglerSF LittmanDR TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function Nature. 2008 453 236 240 Search in Google Scholar

Ye D, Wang Z, Ye J, Wang M, Liu J, Xu Y, Jiang H, Chen J, Wan J. Interleukin-5 levels are decreased in the plasma of coronary artery disease patients and inhibit Th1 and Th17 differentiation in vitro. Rev. Esp. Cardiol. 2020; 73: 393–402. YeD WangZ YeJ WangM LiuJ XuY JiangH ChenJ WanJ Interleukin-5 levels are decreased in the plasma of coronary artery disease patients and inhibit Th1 and Th17 differentiation in vitro Rev. Esp. Cardiol. 2020 73 393 402 Search in Google Scholar

Liu H, Rohowsky-Kochan C. Interleukin-27-Mediated Suppression of Human Th17 Cells Is Associated with Activation of STAT1 and Suppressor of Cytokine Signaling Protein. J. Interferon Cytokine Res. 2011; 31: 459–469. LiuH Rohowsky-KochanC Interleukin-27-Mediated Suppression of Human Th17 Cells Is Associated with Activation of STAT1 and Suppressor of Cytokine Signaling Protein J. Interferon Cytokine Res. 2011 31 459 469 Search in Google Scholar

Cooney LA, Towery K, Endres J, Fox DA. Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J. Immunol. 2011; 187: 4440–4450. CooneyLA ToweryK EndresJ FoxDA Sensitivity and resistance to regulation by IL-4 during Th17 maturation J. Immunol. 2011 187 4440 4450 Search in Google Scholar

Chen Z, Tato CM, Muul L, Laurence A, O’Shea JJ. Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum. 2007; 56: 2936–2946. ChenZ TatoCM MuulL LaurenceA O’SheaJJ Distinct regulation of interleukin-17 in human T helper lymphocytes Arthritis Rheum. 2007 56 2936 2946 Search in Google Scholar

Wilson NJ, Boniface K, Chan JR, McKenzie B, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 2007; 8: 950–957. WilsonNJ BonifaceK ChanJR McKenzieB BlumenscheinWM MattsonJD BashamB SmithK ChenT MorelF LecronJC KasteleinRA CuaDJ McClanahanTK BowmanEP de Waal MalefytR Development, cytokine profile and function of human interleukin 17-producing helper T cells Nat. Immunol. 2007 8 950 957 Search in Google Scholar

Van Beelen AJ, Zelinkova Z, Taanman-Kueter EW, Muller FJ, Hommes DW, Zaat SA, Kapsenberg ML, de Jong EC. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity. 2007; 27: 1–10. Van BeelenAJ ZelinkovaZ Taanman-KueterEW MullerFJ HommesDW ZaatSA KapsenbergML de JongEC Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells Immunity. 2007 27 1 10 Search in Google Scholar

Wang J, Zhao X, Wan YY. Intricacies of TGF-β signaling in Treg and Th17 cell biology. Cell Mol Immunol. 2023; 20:1002–1022. WangJ ZhaoX WanYY Intricacies of TGF-β signaling in Treg and Th17 cell biology Cell Mol Immunol. 2023 20 1002 1022 Search in Google Scholar

Rouvier E, Luciani MF, Mattei MG, Denizot F, Golstein P. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 1993; 150: 5445–5456. RouvierE LucianiMF MatteiMG DenizotF GolsteinP CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene J. Immunol. 1993 150 5445 5456 Search in Google Scholar

Meehan EV, Wang K. Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer. Genes (Basel). 2022; 13:1643. MeehanEV WangK Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer Genes (Basel). 2022 13 1643 Search in Google Scholar

Sánchez-Rodríguez G, Puig L. Pathogenic Role of IL-17 and Therapeutic Targeting of IL-17F in Psoriatic Arthritis and Spondyloarthropathies. Int J Mol Sci. 2023; 24:10305. Sánchez-RodríguezG PuigL Pathogenic Role of IL-17 and Therapeutic Targeting of IL-17F in Psoriatic Arthritis and Spondyloarthropathies Int J Mol Sci. 2023 24 10305 Search in Google Scholar

Harris KM, Clements MA, Kwilasz AJ, Watkins LR. T cell transgressions: Tales of T cell form and function in diverse disease states. Int Rev Immunol. 2022; 41: 475–516. HarrisKM ClementsMA KwilaszAJ WatkinsLR T cell transgressions: Tales of T cell form and function in diverse disease states Int Rev Immunol. 2022 41 475 516 Search in Google Scholar

Meehan EV, Kepeng W. Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer. Genes (Basel). 2022; 13: 1643. MeehanEV KepengW Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer Genes (Basel). 2022 13 1643 Search in Google Scholar

Liu X, Sun S, Liu D. IL-17D: A Less Studied Cytokine of IL-17 Family. Int. Arch. Allergy Immunol. 2020; 181: 618–623. LiuX SunS LiuD IL-17D: A Less Studied Cytokine of IL-17 Family Int. Arch. Allergy Immunol. 2020 181 618 623 Search in Google Scholar

Kostareva OS, Gabdulkhako AG, Kolyadenko IA, Garber MB, Tishchenko SV. Interleukin17: Functional and Structural Features, Application as a Therapeutic Target. Biochemistry (Mosc). 2019; 84(Suppl 1): S193–S205. KostarevaOS GabdulkhakoAG KolyadenkoIA GarberMB TishchenkoSV Interleukin17: Functional and Structural Features, Application as a Therapeutic Target Biochemistry (Mosc) 2019 84 Suppl 1 S193 S205 Search in Google Scholar

Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, Tocker J, Peschon J. Cutting edge: interleukin 17 signals through a heteromeric receptorcomplex, J. Immunol. 2006; 177: 3639. ToyD KuglerD WolfsonM Vanden BosT GurgelJ DerryJ TockerJ PeschonJ Cutting edge: interleukin 17 signals through a heteromeric receptorcomplex J. Immunol. 2006 177 3639 Search in Google Scholar

Ramirez Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L, Jr. Singh H, Ouyang W, Pappu R. IL17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat. Immunol. 2011; 12: 11591166. Ramirez CarrozziV SambandamA LuisE LinZ JeetS LeschJ HackneyJ KimJ ZhouM LaiJ ModrusanZ SaiT LeeW XuM CaplaziP DiehlL de VossJ BalazsM GonzalezLJr SinghH OuyangW PappuR IL17C regulates the innate immune function of epithelial cells in an autocrine manner Nat. Immunol. 2011 12 1159 1166 Search in Google Scholar

Li X, Bechara R, Zhao J, McGeachy MJ, Gaffen SL. IL-17 receptor-based signaling and implications for disease. Nat Immunol. 2019; 20: 1594–1602. LiX BecharaR ZhaoJ McGeachyMJ GaffenSL IL-17 receptor-based signaling and implications for disease Nat Immunol. 2019 20 1594 1602 Search in Google Scholar

Rickel EA, Siegel LA, Yoon BRP, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL. Identification of functional roles for both IL17RB and IL17RA in mediating IL25 induced activities. J. Immunol. 2008; 181: 42994310. RickelEA SiegelLA YoonBRP RottmanJB KuglerDG SwartDA AndersPM TockerJE ComeauMR BudelskyAL Identification of functional roles for both IL17RB and IL17RA in mediating IL25 induced activities J. Immunol. 2008 181 4299 4310 Search in Google Scholar

Shi Y, Ullrich SJ, Zhang J, Connolly K, Grzegorzewski KJ, Barber MC, Wang W, Wathen K, Hodge V, Fisher CL, Olsen H, Ruben SM, Knyazev I, Cho YH, Kao V, Wilkinson KA, Carrell JA, Ebner R. A novel cytokine receptorlig and pair. Identification, molecular characterization, and in vivo immunomodulatory activity. J. Biol. Chem. 2000; 275: 1916719176. ShiY UllrichSJ ZhangJ ConnollyK GrzegorzewskiKJ BarberMC WangW WathenK HodgeV FisherCL OlsenH RubenSM KnyazevI ChoYH KaoV WilkinsonKA CarrellJA EbnerR A novel cytokine receptorlig and pair. Identification, molecular characterization, and in vivo immunomodulatory activity J. Biol. Chem. 2000 275 19167 19176 Search in Google Scholar

Monin L, Gaffen SL. Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications. Cold Spring Harb Perspect Biol. 2018; 10: a028522. MoninL GaffenSL Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications Cold Spring Harb Perspect Biol. 2018 10 a028522 Search in Google Scholar

Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O’Shea JJ. Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling. Nature. 2010; 467: 967–971. GhoreschiK LaurenceA YangXP TatoCM McGeachyMJ KonkelJE RamosHL WeiL DavidsonTS BouladouxN GraingerJR ChenQ KannoY WatfordWT SunHW EberlG ShevachEM BelkaidY CuaDJ ChenW O’SheaJJ Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling Nature. 2010 467 967 971 Search in Google Scholar

Geremia A, Arancibia-Cárcamo CV, Fleming MP, Rust N, Singh B, Mortensen NJ, Travis SP, Powrie F. IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease. J Exp Med. 2011; 208: 1127–1133. GeremiaA Arancibia-CárcamoCV FlemingMP RustN SinghB MortensenNJ TravisSP PowrieF IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease J Exp Med. 2011 208 1127 1133 Search in Google Scholar

Sherlock JP, Joyce-Shaikh B, Turner SP, Chao CC, Sathe M, Grein J, Gorman DM, Bowman EP, McClanahan TK, Yearley JH, Eberl G, Buckley CD, Kastelein RA, Pierce RH, Laface DM, Cua DJ. IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8-entheseal resident T cells. Nat Med. 2012; 18: 1069–1076. SherlockJP Joyce-ShaikhB TurnerSP ChaoCC SatheM GreinJ GormanDM BowmanEP McClanahanTK YearleyJH EberlG BuckleyCD KasteleinRA PierceRH LafaceDM CuaDJ IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8-entheseal resident T cells Nat Med. 2012 18 1069 1076 Search in Google Scholar

Von Stebut E, Boehncke WH, Ghoreschi K, Gori T, Kaya Z, Thaci D, Schäffler A. IL-17A in Psoriasis and Beyond: Cardiovascular and Metabolic Implications. Front Immunol. 2020; 10: 3096. Von StebutE BoehnckeWH GhoreschiK GoriT KayaZ ThaciD SchäfflerA IL-17A in Psoriasis and Beyond: Cardiovascular and Metabolic Implications Front Immunol. 2020 10 3096 Search in Google Scholar

Kolls JK, Lindén A. Interleukin-17 family members and inflammation. Immunity. 2004; 21: 467–476. KollsJK LindénA Interleukin-17 family members and inflammation Immunity. 2004 21 467 476 Search in Google Scholar

Wróbel T, Mazur G, Lindner K, Ziółkowska J. IL−17 as a Mediator of Inflammation and Angiogenesis. Adv. Clin. Exp. Med. 2005; 14: 555–558. WróbelT MazurG LindnerK ZiółkowskaJ IL−17 as a Mediator of Inflammation and Angiogenesis Adv. Clin. Exp. Med. 2005 14 555 558 Search in Google Scholar

Zhang N, Van Zele T, Perez-Novo C, Van Bruaene N, Holtappels G, DeRuyck N, Van Cauwenberge P, Bachert C. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J. Allergy Clin. Immunol. 2008; 122: 961–968. ZhangN Van ZeleT Perez-NovoC Van BruaeneN HoltappelsG DeRuyckN Van CauwenbergeP BachertC Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease J. Allergy Clin. Immunol. 2008 122 961 968 Search in Google Scholar

Derycke L, Zhang N, Holtappels G, Dutré T, Bachert C. IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis. J. Cyst. Fibros. 2012; 11: 193–200. DeryckeL ZhangN HoltappelsG DutréT BachertC IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis J. Cyst. Fibros. 2012 11 193 200 Search in Google Scholar

Wang M, Zhang N, Zheng M, Li Y, Meng L, Ruan Y, Ruan Y, Han J, Zhao N, Wang X, Zhang L, Bachert C. Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol. 2019; 144: 1254–1264. WangM ZhangN ZhengM LiY MengL RuanY RuanY HanJ ZhaoN WangX ZhangL BachertC Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps J. Allergy Clin. Immunol. 2019 144 1254 1264 Search in Google Scholar

Van Bruaene N, Perez Novo C, Deruyck N, Holtappels G, Van Cauwenberge P, Bachert C. Inflammation and remodeling patterns in early-stage chronic rhinosinusitis. Clin. Exp. Allergy. 2012; 42: 883–890. Van BruaeneN Perez NovoC DeruyckN HoltappelsG Van CauwenbergeP BachertC Inflammation and remodeling patterns in early-stage chronic rhinosinusitis Clin. Exp. Allergy. 2012 42 883 890 Search in Google Scholar

Ramezanpour M, Moraitis S, Smith JLP, Wormald PJ, Vreugde S. Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis. Mediators Inflamm. 2016; 2016: 9798206. RamezanpourM MoraitisS SmithJLP WormaldPJ VreugdeS Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis Mediators Inflamm. 2016 2016 9798206 Search in Google Scholar

Jiang XD, Li GY, Li L, Dong Z, Zhu DD. The Characterization of IL-17A Expression in Patients with Chronic Rhinosinusitis with Nasal Polyps. Am. J. Rhinol. Allergy. 2011; 25: e171–175. JiangXD LiGY LiL DongZ ZhuDD The Characterization of IL-17A Expression in Patients with Chronic Rhinosinusitis with Nasal Polyps Am. J. Rhinol. Allergy. 2011 25 e171 175 Search in Google Scholar

Makihara S, Okano M, Fujiwara T, Kariya S, Noda Y, Higaki T, Nishizaki K. Regulation and characterization of IL-17A expression in patients with chronic rhinosinusitis and its relationship with eosinophilic inflammation. J. Allergy Clin. Immunol. 2010; 126: 397–400. MakiharaS OkanoM FujiwaraT KariyaS NodaY HigakiT NishizakiK Regulation and characterization of IL-17A expression in patients with chronic rhinosinusitis and its relationship with eosinophilic inflammation J. Allergy Clin. Immunol. 2010 126 397 400 Search in Google Scholar

Saitoh T, Kusunoki T, Yao T, Kawano K, Kojima Y, Miyahara K, Onoda J, Yokoi H, Ikeda K. Role of Interleukin-17A in the Eosinophil Accumulation and Mucosal Remodeling in Chronic Rhinosinusitis with Nasal Polyps Associated with Asthma. Int. Arch. Allergy Immunol. 2010; 151: 8–16. SaitohT KusunokiT YaoT KawanoK KojimaY MiyaharaK OnodaJ YokoiH IkedaK Role of Interleukin-17A in the Eosinophil Accumulation and Mucosal Remodeling in Chronic Rhinosinusitis with Nasal Polyps Associated with Asthma Int. Arch. Allergy Immunol. 2010 151 8 16 Search in Google Scholar

Hu XD, Bao YY, Zhou SH, Yao HT, Mao JY, Ji XX, Wu XH. Interleukin-17A expression in patients with chronic rhinosinusitis and its relationship with clinical features. J. Int. Med. Res. 2013; 41: 777–784. HuXD BaoYY ZhouSH YaoHT MaoJY JiXX WuXH Interleukin-17A expression in patients with chronic rhinosinusitis and its relationship with clinical features J. Int. Med. Res. 2013 41 777 784 Search in Google Scholar

Chapurin N, Li P, Chandra RK, Turner JH, Chowdhury NI. Elevated mucus interleukin-17A levels are associated with increased prior sinus surgery for chronic rhinosinusitis. Int. Forum Allergy Rhinol. 2021; 11: 120–127. ChapurinN LiP ChandraRK TurnerJH ChowdhuryNI Elevated mucus interleukin-17A levels are associated with increased prior sinus surgery for chronic rhinosinusitis Int. Forum Allergy Rhinol. 2021 11 120 127 Search in Google Scholar

Language:
English
Publication timeframe:
1 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Microbiology and Virology, Medicine, Basic Medical Science, Immunology