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The effect of curcumin on symptoms and quality of life in patients with irritable bowel syndrome

Małgorzata Woźniak

Małgorzata Woźniak

Medical University of Łódź, Department of Digestive Tract DiseasesŁódź, Poland
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Woźniak, Małgorzata
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Adam Fabisiak

Adam Fabisiak

Medical University of Łódź, Department of Digestive Tract DiseasesŁódź, Poland
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Fabisiak, Adam
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Renata Talar-Wojnarowska

Renata Talar-Wojnarowska

Medical University of Łódź, Department of Digestive Tract DiseasesŁódź, Poland
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Talar-Wojnarowska, Renata
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Ewa Małecka-Wojciesko

Ewa Małecka-Wojciesko

Medical University of Łódź, Department of Digestive Tract DiseasesŁódź, Poland
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Małecka-Wojciesko, Ewa
  
Aug 09, 2022
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Article Category: Original Study
Published Online: Aug 09, 2022
Page range: 345 - 350
Received: Jan 18, 2022
Accepted: May 15, 2022
DOI: https://doi.org/10.2478/ahem-2022-0048
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© 2022 Małgorzata Woźniak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

Disease activity scores on the IBS-SSS scale at initiation of treatment (visit 0) and after 4 (visit 1) and 12 weeks (visit 2) of curcumin treatment (mean ± SD), * p < 0.05 compared to visit 0, ** p < 0.01 compared to visit 1
Disease activity scores on the IBS-SSS scale at initiation of treatment (visit 0) and after 4 (visit 1) and 12 weeks (visit 2) of curcumin treatment (mean ± SD), * p < 0.05 compared to visit 0, ** p < 0.01 compared to visit 1

Fig. 2

Changes in individual categories of IBS-SSS from the start of treatment (visit 0), after 4 (visit 1), and 12 weeks (visit 2) of curcumin consumption * p < 0.05, compared to visit 0, ** p < 0,01, compared to visit 0
Changes in individual categories of IBS-SSS from the start of treatment (visit 0), after 4 (visit 1), and 12 weeks (visit 2) of curcumin consumption * p < 0.05, compared to visit 0, ** p < 0,01, compared to visit 0

Fig. 3

Results of overall quality of life scale (IBS-QoL) at initiation of treatment (visit 0) and after 4 (visit 1) and 12 weeks (visit 2) of curcumin consumption (mean ± SD). * p < 0.05 compared to visit 0, ** p < 0.01 compared to visit 1
Results of overall quality of life scale (IBS-QoL) at initiation of treatment (visit 0) and after 4 (visit 1) and 12 weeks (visit 2) of curcumin consumption (mean ± SD). * p < 0.05 compared to visit 0, ** p < 0.01 compared to visit 1

Fig. 4

Quality of life results in individual domains at the start of treatment (visit 0), after 4 (visit 1), and after 12 weeks (visit 2) of curcumin use. * p < 0.05, compared to visit 0, ** p < 0.05, compared to visit 0
Quality of life results in individual domains at the start of treatment (visit 0), after 4 (visit 1), and after 12 weeks (visit 2) of curcumin use. * p < 0.05, compared to visit 0, ** p < 0.05, compared to visit 0

Characteristics of the study group

nSex 51
female n (%) 30 (58.8) p = 0.08
male n (%) 21 (41.2)
Age (years) 52.6 ± 15.9
female 56.9 ± 14.2 p = 0.02
male 46.6 ± 16.5
Severity of IBSn (%) mild 4 (7.8) p = 0.55
moderate 25 (49.0)
severe 22 (43.2)
Type of IBSn (%) diarrhea 35 (68.6) p < 0.05
constipation 16 (31.4)
Language:
English
Publication timeframe:
1 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Microbiology and Virology, Medicine, Basic Medical Science, Immunology
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