Wiltfang et al. [15] |
1999 |
36/no control group |
S100B serum level has advantage over ammonia serum level in detecting portal-systemic encephalopathy |
Vaquero et al. [16] |
2003 |
54/no control group |
S100B serum level has no correlation with HE severity and liver function |
Saleh et al. [17] |
2007 |
43/9 |
S100B level has correlation with HE (stages I and II), compared to healthy and cirrhotic patients without HE |
Isobe-Harima et al. [18] |
2008 |
9/no control group |
S100B serum level is higher in HE patients |
Duarte Rojo et al. [19] |
2016 |
46/15 |
S100B serum levels are higher in patients with cirrhosis and HE than in healthy subjects |
Toney et al. [21] |
2019 |
82/no control group |
no correlation between serum S100B level and severity of HE |
Strebel et al. [20] |
2020 |
30/no control group |
serum S100B protein level correlated with the presence of HE |