1. bookVolume 71 (2021): Issue 1 (March 2021)
Journal Details
License
Format
Journal
eISSN
1820-7448
First Published
25 Mar 2014
Publication timeframe
4 times per year
Languages
English
access type Open Access

Sarcoid in the Lower Eyelid Due to Bovine Papillomavirus-2 in a Donkey (Equus Asinus)

Published Online: 22 Mar 2021
Volume & Issue: Volume 71 (2021) - Issue 1 (March 2021)
Page range: 131 - 136
Received: 16 Dec 2020
Accepted: 02 Feb 2021
Journal Details
License
Format
Journal
eISSN
1820-7448
First Published
25 Mar 2014
Publication timeframe
4 times per year
Languages
English
Abstract

Sarcoid tumors were described by means of histopathological and molecular procedures in a 5-year-old donkey. Histopathological examination showed epithelial changes including hyperkeratosis, epithelial hyperplasia, koilocytosis, and rete peg formation. Neoplastic fibroblastic cells were plumb, large spindle to stellate and embedded in dense collagenous tissue. Results of Polymerase Chain Reaction and DNA sequence analysis showed that the etiological agent belonged to Bovine Papilloma Virus-II species in the delta papilloma virus genus. This case study represents the first report demonstrating the presence of Bovine Papilloma Virus-II in donkey sarcoid.

Keywords

1. Munday JS, Kiupel M: Papillomavirus-Associated Cutaneous Neoplasia in Mammals. Vet Pathol 2010, 47(2):254–264.10.1177/0300985809358604 Search in Google Scholar

2. Munday JS: Bovine and Human Papillomaviruses: A Comparative Review. Vet Pathol 2014, 51(6): 1063–1075.10.1177/0300985814537837 Search in Google Scholar

3. Bernard HU, Burk RD, Chen Z, Van Doorslaer K, Zur Hausen H, De Villiers EM: Classification of papillomaviruses (PVs) based on 189 PV types and pro posal of taxonomic amendments. Virology 2010, 401:70-79.10.1016/j.virol.2010.02.002 Search in Google Scholar

4. Otten N, Tscharner C, Lazary S, Antczak DF, Gerber H: DNA of bovine papillomavirus type 1 and 2 in equine sarcoids: PCR detection and direct sequencing. Arch Virol 1993, 132:121-131.10.1007/BF01309847 Search in Google Scholar

5. Martens A, De Moor A, Demeulemeester J, Ducatelle R: Histopathological characteristics of five clinical types of equine sarcoid. Res Vet Sci 2000, 69:295-300.10.1053/rvsc.2000.0432 Search in Google Scholar

6. Dagalp SB, Dogan F, Farzani TA, Salar S, Bastan A: The genetic diversity of bovine papillomaviruses (BPV) from different papillomatosis cases in dairy cows in Turkey. Arch Virol 2017, 162:1507–1518.10.1007/s00705-017-3258-8 Search in Google Scholar

7. Kanat O, Ataseven VS, Babaeski S, Derelli F, Kumas C, Dogan F, Dagalp SB: Equine and bovine papillomaviruses from Turkish brood horses: a molecular identification and immunohistochemical study. Vet Arh 2019, 89(5):601-611.10.24099/vet.arhiv.0507 Search in Google Scholar

8. Wosiacki SR, Barreiro MAB, Alfieri AF, Alfieri AA: Semi-nested PCR for detection and typing of bovine Papillomavirus type 2 in urinary bladder and whole blood from cattle with enzootic haematuria. J Virol Methods 2005, 126:215–219.10.1016/j.jviromet.2005.01.021 Search in Google Scholar

9. Lindsey CL, Almeida ME, Vicari CF, Carvalho C, Yaguiu A, Freitas AC, Beçak W, Stocco RC: Bovine papillomavirus DNA in milk, blood, urine, semen, and spermatozoa of bovine papillomavirus-infected animals. Genet Mol Res 2009, 8 (1):310-318.10.4238/vol8-1gmr573 Search in Google Scholar

10. Lunardi M, De Alcântara BK, Otonel RAA, Rodrigues WB, Alfieri AF, Alfieri AA: Bovine papillomavirus type 13 DNA in equine sarcoids. J. Clin. Microbiol 2013, 51(21):67-71.10.1128/JCM.00371-13 Search in Google Scholar

11. Borzacchiello G, Mogavero S, De Vita G, Roperto S, Della Salda L, Roperto F: Activated platelet derived growth factor b receptor expression, PI3K-AKT pathway molecular analysis and transforming signals in equine sarcoids. Vet Pathol 2009, 46:589–597.10.1354/vp.08-VP-0191-B-FL Search in Google Scholar

12. Borzacchiello G, Russo V, Della Salda L, Roperto S, Roperto F: Expression of platelet-derived growth factor-beta receptor and bovine papillomavirus E5 and E7 oncoproteins in equine sarcoid. J Comp Pathol, 2008, 139:231–237.10.1016/j.jcpa.2008.07.006 Search in Google Scholar

13. Epperson ED, Castleman WL. Bovine Papillomavirus DNA and S100 Profiles in Sarcoids and Other Cutaneous Spindle Cell Tumors in Horses. Veterinary Pathology. 2017;54 (1):44-52.10.1177/0300985816653169 Search in Google Scholar

14. Nasir L, McFarlane ST, Torrontegui BO, Reid SW: Screening for bovine papillomavirus in peripheral blood cells of donkeys with and without sarcoids. Res Vet Sci 1997, 63(3):289-290.10.1016/S0034-5288(97)90036-9 Search in Google Scholar

15. Koch C, Ramsauer AS, Drögemüller M, Ackermann M, Gerber V, Tobler K: Genomic comparison of bovine papillomavirus 1 isolates from bovine, equine and asinine lesional tissue samples. Virus Res 2018, 15;244:6-12.10.1016/j.virusres.2017.11.005 Search in Google Scholar

16. Chambers G, Ellsmore VA, O’Brien PM, Reid SWJ, Love S, Campo MS, Nasir L: Association of bovine papillomavirus with the equine sarcoid. J Gen Virol 2003, 84:1055-1062.10.1099/vir.0.18947-0 Search in Google Scholar

Recommended articles from Trend MD

Plan your remote conference with Sciendo