<abstract xmlns="http://www.w3.org/1999/xhtml"><p> In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum nuclear diameter (D min, μm) and maximum nuclear diameter (D max, μm) were studied and compared to metastases in regional lymph nodes. The mean values of these parameters were signifi cantly greater in cats with lymph node metastases compared to parameters of tumour cells from cats which were lymph node-negative. A signifi cant positive correlation was observed between all studied morphometric parameters and metastases in the regional lymph nodes. In conclusion, computer -assisted nuclear morphometry could be used as a prognostic method in the diagnosis of spontaneous feline cutaneous squamous cell carcinomas.</p></abstract>

In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum nuclear diameter (D min, μm) and maximum nuclear diameter (D max, μm) were studied and compared to metastases in regional lymph nodes. The mean values of these parameters were signifi cantly greater in cats with lymph node metastases compared to parameters of tumour cells from cats which were lymph node-negative. A signifi cant positive correlation was observed between all studied morphometric parameters and metastases in the regional lymph nodes. In conclusion, computer -assisted nuclear morphometry could be used as a prognostic method in the diagnosis of spontaneous feline cutaneous squamous cell carcinomas.

Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area...

Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas

Published Online: Oct 03, 2018

Page range: 251 - 256

Received: Jun 11, 2018

Accepted: Aug 28, 2018

DOI: https://doi.org/10.2478/acve-2018-0022

Keywords
nuclear morphometry, feline cutaneous squamous cell carcinomas, metastases, prognosis

© 2018 Simeonov Radostina, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas

Published Online: Oct 03, 2018

Page range: 251 - 256

Received: Jun 11, 2018

Accepted: Aug 28, 2018

DOI: https://doi.org/10.2478/acve-2018-0022

Keywordsnuclear morphometry, feline cutaneous squamous cell carcinomas, metastases, prognosis

© 2018 Simeonov Radostina, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
nuclear morphometry, feline cutaneous squamous cell carcinomas, metastases, prognosis