Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide
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May 27, 2014
![Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide's Cover Image](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6470799b71e4585e08a9e01d/cover-image.jpg)
About this article
Published Online: May 27, 2014
Page range: 34 - 37
DOI: https://doi.org/10.2478/acs-2014-0007
Keywords
© Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava
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The title compound, C11H16NOS・I, is chiral molecule with three stereogenic centres. The absolute configuration was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine moiety adopts a half-chair conformation with atom displaced by 0.655 (2) A from the plane of the oder remaining five atoms. The pyrrolidine ring adopts an envelope conformation, with the greatest deviation from the mean plane of the ring being 0.646 (2) A for the bridgehead N atom. The crystal structure of the title compound is stabilized by O-H・・・I and C-H・・・O hydrogen bonds.