1. bookVolume 72 (2022): Issue 3 (September 2022)
Journal Details
License
Format
Journal
eISSN
1846-9558
First Published
28 Feb 2007
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4 times per year
Languages
English
access type Open Access

The effectiveness of dexamethasone as a combination therapy for COVID-19

Published Online: 13 Apr 2022
Volume & Issue: Volume 72 (2022) - Issue 3 (September 2022)
Page range: 345 - 358
Accepted: 28 Jan 2022
Journal Details
License
Format
Journal
eISSN
1846-9558
First Published
28 Feb 2007
Publication timeframe
4 times per year
Languages
English
Abstract

Coronavirus disease 2019 (COVID-19) was reported as a global pandemic in March 2020 after invading many countries and leaving behind tens of thousands of infected patients in a brief time span. Approval of a few vaccines has been obtained and their efficacy of varying degrees established. Still, there is no effective pharmaceutical agent for the treatment of COVID-19 though several drugs are undergoing clinical trials. Recent studies have shown that dexamethasone, a corticosteroid, can reduce the rate of COVID-19-related mortality in the intensive care unit by 35 % for patients who are on mechanical ventilation. Although variable efficacy of other combination therapies has been reported for treating COVID-19 associated with acute respiratory distress syndrome (ARDS), dexamethasone is an extensively used drug in many treatment regimens against COVID-19. The current review aims to explore the role of dexamethasone as an efficient combination treatment for COVID-19.

Keywords

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