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Acta Pharmaceutica
Volume 71 (2021): Issue 4 (December 2021)
Open Access
New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation
Dima A. Sabbah
Dima A. Sabbah
,
Bara’a A. Al-Azaideh
Bara’a A. Al-Azaideh
,
Wamidh H. Talib
Wamidh H. Talib
,
Rima Hajjo
Rima Hajjo
,
Kamal Sweidan
Kamal Sweidan
,
Aya M. Al-Zuheiri
Aya M. Al-Zuheiri
,
Ghassan Abu Sheikha
Ghassan Abu Sheikha
and
Sawsan Shraim
Sawsan Shraim
| Apr 03, 2021
Acta Pharmaceutica
Volume 71 (2021): Issue 4 (December 2021)
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Published Online:
Apr 03, 2021
Page range:
545 - 565
Accepted:
Dec 08, 2020
DOI:
https://doi.org/10.2478/acph-2021-0043
Keywords
sulfonylhydrazones
,
antitumor
,
HCT-116
,
PI3Kα-inhibitors
,
cheminformatics
,
docking
© 2021 Dima A. Sabbah et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Dima A. Sabbah
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan
Bara’a A. Al-Azaideh
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan
Wamidh H. Talib
Department of Clinical Pharmacy and Therapeutics, Applied Science Private University
Jordan
Rima Hajjo
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan
Kamal Sweidan
Department of Chemistry, The University of Jordan
Jordan
Aya M. Al-Zuheiri
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan
Ghassan Abu Sheikha
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan
Visiting Professor Scholar, Skaggs School of Pharmacy and Pharmaceutical Science University of California
Sawsan Shraim
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan
Jordan