[1. P. D. Darbre, Endocrine Disruption and Human Health, Elsevier Science, Amsterdam 2015, pp. 4–23, 28–43.]Search in Google Scholar
[2. World Health Organization and United Nations Environment Programme, State of the Science of Endocrine Disrupting Chemicals – 2012, An assessment of the state of the science of endocrine disruptors prepared by a group of experts for the United Nations Environment Programme and World Health Organization, Inter-Organization Programme For the Sound Management of Chemicals, (Eds. Å. Bergman, J. J. Heindel, S. Jobling, K. A. Kidd and R. T. Zoeller), WHO Library Cataloguingin-Publication Data, Geneva 2013; https://www.who.int/ceh/publications/endocrine/en/; last access date December 19, 2019]Search in Google Scholar
[3. L. N. Vandenberg, T. Colborn, T. B. Hayes, J. J. Heindel, D. R. Jacobs, Jr., D.-H. Lee, T. Shioda, A. M. Soto, F. S. vom Saal, W. V. Welshons, R. T. Zoeller and J. P. Myers, Hormones and endocrine-disrupting chemicals: Low dose effects and nonmonotonic dose responses, Endocr. Rev.33 (2012) 378–455; https://doi.org/10.1210/er.2011-105010.1210/er.2011-1050336586022419778]Search in Google Scholar
[4. A. Myridakis, E. Fthenou, E. Balaska, M. Vakinti, M. Kogevinas and E. G. Stephanou, Phthalate esters, parabens and bisphenol-A exposure among mothers and their children in Greece (Rhea cohort), Environ. Int.83 (2015) 1–10; https://doi.org/10.1016/j.envint.2015.05.01410.1016/j.envint.2015.05.01426072145]Search in Google Scholar
[5. Y. Guo and K. Kannan, A survey of phthalates and parabens in personal care products from the United States and its implications for human exposure, Environ. Sci. Technol.47 (2013) 14442–14449; https://doi.org/10.1021/es404203410.1021/es404203424261694]Search in Google Scholar
[6. American Council on Science and Health, Fear of Parabens Compromises Safety of Certain Cosmetic Products, ACSH, New York, August 2014; https://www.acsh.org/news/2014/08/26/fear-parabens-compromises-safety-certain-cosmetic-products; last access date December 19, 2019.]Search in Google Scholar
[7. McGill University, Office for Science and Society, Separating Sense from Nonsense, J. Schwarcz, Paraben phobia is unjustified, Pseudoscience, March 20, 2017; https://www.mcgill.ca/oss/article/cancer-controversial-science-cosmetics-health-news-quackery-toxicity/joe-schwarczs-right-chemistry-paraben-phobia-unjustified; last access date December 19, 2019.]Search in Google Scholar
[8. P. J. Sheskey, W. G. Cook and C. G. Cable, Handbook of Pharmaceutical Excipients, 8th ed., Pharmaceutical Press, London, and American Pharmacists Association, Washington D.C. 2017, pp. 130–133, 379–382, 604–608, 803–806.]Search in Google Scholar
[9. C. G. Abrantes, D. Duarte and C. P. Reis, An overview of pharmaceutical excipients: Safe or not safe?, J. Pharm. Sci.105 (2016) 2019–2026; https://doi.org/10.1016/j.xphs.2016.03.01910.1016/j.xphs.2016.03.01927262205]Search in Google Scholar
[10. M. G. Soni, I. G. Carabin and G. A. Burdock, Safety assessment of esters of p-hydroxybenzoic acid (parabens), Food Chem. Toxicol.43 (2005) 985–1015; https://doi.org/10.1016/j.fct.2005.01.02010.1016/j.fct.2005.01.02015833376]Search in Google Scholar
[11. C. Liao, F. Liu and K. Kannan, Occurrence of and dietary exposure to parabens in foodstuffs from the United States, Environ. Sci. Technol. 47 (2013) 3918–3925; https://doi.org/10.1021/es400724s10.1021/es400724s23506043]Search in Google Scholar
[12. P. D. Darbre, A. Aljarrah, W. R. Miller, N. G. Coldham, M. J. Sauer and G. S. Pope, Concentrations of parabens in human breast tumours, J. Appl. Toxicol.24 (2004) 5–13; https://doi.org/10.1002/jat.95810.1002/jat.95814745841]Search in Google Scholar
[13. N. Raza, K.-H. Kim, M. Abdullah, W. Raza and R. J. C. Brown, Recent developments in analytical quantitation approaches for parabens in human-associated sample, Trends Anal. Chem. 98 (2018) 161–173; https://doi.org/10.1016/j.trac.2017.11.00910.1016/j.trac.2017.11.009]Search in Google Scholar
[14. M. Fisher, S. MacPherson, J. M. Braun, R. Hauser, M. Walker, M. Feeley, R. Mallick, R. Bérubé and T. E. Arbuckle, Paraben concentrations in maternal urine and breast milk and its association with personal care product use, Environ. Sci. Technol.51 (2017) 4009–4017; https://doi.org/10.1021/acs.est.6b0430210.1021/acs.est.6b0430228318231]Search in Google Scholar
[15. S. Shekhar, S. Sood, S. Showkat, C. Lite, A. Chandrasekhar, M. Vairamani, S. Barathi and W. Santosh, Detection of phenolic endocrine disrupting chemicals (EDCs) from maternal blood plasma and amniotic fluid in Indian population, Gen. Comp. Endocr. 241 (2017) 100–107; https://doi.org/10.1016/j.ygcen.2016.05.02510.1016/j.ygcen.2016.05.02527235644]Search in Google Scholar
[16. E. V. S Hessel, P. E. Boon, S.P. den Braver-Sewradj, J. A. J. Meesters, M. Weda and W. Brand, Review on butylparaben: exposure, toxicity and risk assessment – With a focus on endocrine disrupting properties and cumulative risk assessment, The Netherlands Food and Consumer Product Safety Authority (NVWA), National Institute for Public Health and the Environment, RIVM Report 2018-0161, Bilthoven (The Netherlands) 2018; https://www.rivm.nl/bibliotheek/rapporten/2018-0161.pdf; last access date October 30, 2019.]Search in Google Scholar
[17. W. Brand, P. E. Boon, E. V. S. Hessel, J. A. J. Meesters, M. Weda and A. G. Schuur, Exposure to and toxicity of methyl-, ethyl- and propylparaben – A literature review with a focus on endocrine-disrupting properties, RIVM Report 2017-0028, The Netherlands Food and Consumer Product Safety Authority (NVWA), National Institute for Public Health and the Environment, RIVM Report 2018-0161, Bilthoven (The Netherlands) 2018; https://www.rivm.nl/bibliotheek/rapporten/2017-0028.pdf; last access date October 30, 2019.]Search in Google Scholar
[18. European Commision (EC), Scientific Committee on Consumer Safety (SCCS), Opinion on Parabens. Updated Request for a Scientific Opinion on Propyl- and Butylparaben; SCCS/1514/13, SCCS, Luxembourg, May 3, 2013; https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_132.pdf; last access date October 29, 2019.]Search in Google Scholar
[19. N. R. Janjua, H. Fredericksen, N. E. Skakkebaek, H. C. Wulf and A. M. Andersson, Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans, Int. J. Androl.31 (2008) 118–130; https://doi.org/10.1111/j.1365-2605.2007.00841.x10.1111/j.1365-2605.2007.00841.x]Search in Google Scholar
[20. R. T. Engeli, S. R. Rohrer, A. Vuorinen, S. Herdlinger, T. Kaserer, S. Leugger, D. Schuster and A. Oder-matt, Interference of paraben compounds with estrogen metabolism by inhibition of 17β-hydroxysteroid dehydrogenases, Int. J. Mol. Sci. 18 (2017) 1–13; https://doi.org/10.3390/ijms1809200710.3390/ijms18092007]Search in Google Scholar
[21. M. Y. Shin, C. Shin, J. W. Choi, J. Lee, S. Lee and S. Kim, Pharmacokinetic profile of propyl paraben in humans after oral administration, Environ. Int.130 (2019) Article ID 104917 (9 pages); https://doi.org/10.1016/j.envint.2019.10491710.1016/j.envint.2019.104917]Search in Google Scholar
[22. M. G. Soni, S. L. Taylor, N. A. Greenberg and G. A. Burdock, Evaluation of the health aspects of methyl paraben: a review of the published literature, Food Chem. Toxicol.40 (2002) 1335–1373; https://doi.org/10.1016/S0278-6915(02)00107-210.1016/S0278-6915(02)00107-2]Search in Google Scholar
[23. M. Lakeram, A. J. Paine, D. J. Lockley, D. J. Sanders, R. Pendlington and B. Forbes, Transesterification of p-hydroxybenzoate esters (parabens) by human intestinal (Caco-2) cells, Xenobiotica36 (2006) 739–749; https://doi.org/10.1080/0049825060073863710.1080/0049825060073863716971340]Search in Google Scholar
[24. H. M. Harville, R. Voorman and J. J. Prusakiewicz, Comparison of paraben stability in human and rat skin, Drug Metab. Lett.1 (2007) 17–21, https://doi.org/10.2174/18723120777981430010.2174/18723120777981430019356013]Search in Google Scholar
[25. W. L. Ma, X. Zhao, Z. Y. Lin, M. O. Mohammed, Z. F. Zhang, L. Y. Liu, W. W. Song and Y. F. Li, A survey of parabens in commercial pharmaceuticals from China and its implications for human exposure, Environ. Int.95 (2016) 30–35; https://doi.org/10.1016/j.envint.2016.07.01310.1016/j.envint.2016.07.01327476643]Search in Google Scholar
[26. S. M. Bell, X. Chang, J. F. Wambaugh, D. G. Allen, M. Bartels, K. L. R. Brouwer, W. M. Casey, N. Choksi, S. S. Ferguson, G. Fraczkiewicz, A. M. Jarabek, A. Ke, A. Lumen, S. G. Lynn, A. Paini, P. S. Price, C. Ring, T. W. Simon, N. S. Sipes, C. S. Sprankle, J. Strickland, J. Troutman, B. A. Wetmore and N. C. Kleinstreuer, In vitro to in vivo extrapolation for high throughput prioritization and decision making, Toxicol. In Vitro47 (2018) 213–227; https://doi.org/10.1016/j.tiv.2017.11.01610.1016/j.tiv.2017.11.016739369329203341]Search in Google Scholar
[27. A. Kizhedath, S. Wilkinson and J. Glassey, Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models, Toxicol. In Vitro55 (2019) 108–115; https://doi.org/10.1016/j.tiv.2018.12.00710.1016/j.tiv.2018.12.00730572011]Search in Google Scholar
[28. M. Calafat, X. Ye, L. Y. Wong, A. M. Bishop and L. L. Needham, Urinary concentrations of four parabens in the U.S. population, Environ. Health Perspect. 118 (2010) 679–685; https://doi.org/10.1289/ehp.090156010.1289/ehp.0901560286668520056562]Search in Google Scholar
[29. R. S. Tade, M. P. More, V. K. Chatap, P. K. Deshmukh and P. O. Patil, Safety and toxicity of parabens in pharmaceutical and food products, Inventi Rapid Pharm. Pract. No. 3 (2018) 1–9.]Search in Google Scholar
[30. F. Artacho-Cordón, J. P. Arrebola, O. Nielsen, P. Hernández, N. E. Skakkebaek, M. F. Fernández, A. M. Andersson, N. Olea and H. Frederiksen, Assumed nonpersistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum, Environ. Res.156 (2017) 120–127; https://doi.org/10.1016/j.envres.2017.03.03010.1016/j.envres.2017.03.030]Search in Google Scholar
[31. P. M. Ashrap, D. J. Watkins, A. M. Calafat, X. Ye, Z. Rasario, F. Brown, C. M. Vélez-Vegae, A. Alshawabkeh, J. F. Corfero and J. D. Meeker, Elevated concentrations of urinary triclocarban, phenol and paraben among pregnant women in Northern Puerto Rico: predictors and trends, Environ. Int.121 (2018) 990–1002; https://doi.org/10.1016/j.envint.2018.08.02010.1016/j.envint.2018.08.020]Search in Google Scholar
[32. H. Frederiksen, N. Jørgensen and A. M. Andersson, Parabens in urine, serum and seminal plasma from healthy Danish men determined by liquid chromatography–tandem mass spectrometry (LC– MS/MS), J. Expo. Sci. Env. Epid.21 (2011) 262–271; https://doi.org/10.1038/jes.2010.610.1038/jes.2010.6]Search in Google Scholar
[33. B. F. Pycke, L. A. Geer, M. Dalloul, O. Abulafia and R. U. Halden, Maternal and fetal exposure to parabens in a multiethnic urban US population, Environ. Int.84 (2015) 193–200; https://doi.org/10.1016/j.envint.2015.08.01210.1016/j.envint.2015.08.012]Search in Google Scholar
[34. C. V. Towers, P. D. Terry, D. Lewis, B. Howard, W. Chambers, C. Armistead, B. Weitz, S. Porter, C. J. Borman, R. C. M. Kennedy and J. Chen, Transplacental passage of antimicrobial paraben preservatives, J. Expo. Sci. Env. Epid. 25 (2015) 604–607; https://doi.org/10.1038/jes.2015.2710.1038/jes.2015.27]Search in Google Scholar
[35. E. J. Routledge, J. Parker, J. Odum, J. Ashby and J. P. Sumpter, Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic, Toxicol. Appl. Pharmacol.153 (1998) 12–19; https://doi.org/10.1006/taap.1998.854410.1006/taap.1998.8544]Search in Google Scholar
[36. J. R. Byford, L. E. Shaw, M. G. B. Drew, G. S. Pope, M. J. Sauer and P. D. Darbre, Oestrogenic activity of parabens in MCF7 human breast cancer cells, J. Steroid Biochem. Mol. Biol. 80 (2002) 49–60; https://doi.org/10.1016/S0960-0760(01)00174-110.1016/S0960-0760(01)00174-1]Search in Google Scholar
[37. R. Golden, J. Gandy and G. Vollmer, A review of the endocrine activity of parabens and implications for potential risks to human health, Crit. Rev. Toxicol. 35 (2005) 435–458; https://doi.org/10.1080/1040844049092010410.1080/1040844049092010416097138]Search in Google Scholar
[38. A. F. Fransway, P. J. Fransway, D. V. Belsito and J. A. Yiannias, Paraben toxicology, Dermatitis30 (2019) 32–45; https://doi.org/10.1097/DER.000000000000042810.1097/DER.000000000000042830570577]Search in Google Scholar
[39. J. A. van Meeuwen, O. van Son, A. H. Piersma, P. C. de Jong and M. van den Berg, Aromatase inhibiting and combined estrogenic effects of parabens and estrogenic effects of other additives in cosmetics, Toxicol. Appl. Pharmacol. 230 (2008) 372–382; https://doi.org/10.1016/j.taap.2008.03.00210.1016/j.taap.2008.03.00218486175]Search in Google Scholar
[40. R. J. Witorsch and J. A. Thomas, Personal care products and endocrine disruption: A critical review of the literature, Crit. Rev. Toxicol.40 (2010) 1–30; https://doi.org/10.3109/10408444.2010.51556310.3109/10408444.2010.515563]Search in Google Scholar
[41. A. M. Wróbel and E. Ł. Gregoraszczuk, Actions of methyl-, propyl- and butylparaben on estrogen receptor-α and -β and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells, Toxicol. Lett.230 (2014) 375–381; https://doi.org/10.1016/j.toxlet.2014.08.01210.1016/j.toxlet.2014.08.012]Search in Google Scholar
[42. J. H. Lee, M. Lee, C. Ahn, H. Y. Kang, D. N. Tran and E. B. Jeung, Parabens accelerate ovarian dys-function in a 4-vinylcyclohexene diepoxide-induced ovarian failure model, Int. J. Environ. Res. Public Health14 (2017) Article ID 161 (13 pages); https://doi.org/10.3390/ijerph1402016110.3390/ijerph14020161]Search in Google Scholar
[43. Y. Nishihama, J. Yoshinaga, A. Iida, S. Konishi, H. Imai, M. Yoneyama, D. Nakajima and H. Shiraishi, Association between paraben exposure and menstrual cycle in female university students in Japan, Reprod. Toxicol.63 (2016) 107–113; https://doi.org/10.1016/j.reprotox.2016.05.01010.1016/j.reprotox.2016.05.010]Search in Google Scholar
[44. S. Oishi, Effects of butyl paraben on the male reproductive system in mice, Arch. Toxicol.76 (2002) 423–429; https://doi.org/10.1007/s00204-002-0360-810.1007/s00204-002-0360-8]Search in Google Scholar
[45. S. Oishi, Effects of propylparaben on the male reproductive system, Food Chem. Toxicol. 40 (2002) 1807–1813; https://doi.org/10.1016/S0278-6915(02)00204-110.1016/S0278-6915(02)00204-1]Search in Google Scholar
[46. A. M. Hoberman, D. K. Schreur, T. Leazer, G. P. Daston, P. Carthew, T. Re, L. Loretz and P. Mann, Lack of effect of butylparaben and methylparaben on the reproductive system in male rats, Birth Defects Res. B Dev. Reprod. Toxicol.83 (2008) 123–133; https://doi.org/10.1002/bdrb.2015310.1002/bdrb.2015318393383]Search in Google Scholar
[47. S. Khanna, P. R. Dash and P. D. Darbre, Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro, J. Appl. Toxicol. 34 (2014) 1051–1059; https://doi.org/10.1002/jat.300310.1002/jat.300324652746]Search in Google Scholar
[48. P. D. Darbre, Endocrine disruptors and obesity, Curr. Obes. Rep.6 (2017) 18–27; https://doi.org/10.1007/s13679-017-0240-410.1007/s13679-017-0240-4535937328205155]Search in Google Scholar
[49. D. G. Bayülken, B. A. Tüylü, H. Sinan and H. Sivaset, Investigation of genotoxic effects of paraben in cultured human lymphocytes, Drug Chem. Toxicol. 42 (2019) 349–356; https://doi.org/10.1080/01480545.2017.141483410.1080/01480545.2017.141483429281926]Search in Google Scholar
[50. D. G. Bayülken and B. A. Tüylü, In vitro genotoxic and cytotoxic effects of some paraben esters on human peripheral lymphocytes, Drug Chem. Toxicol. 42 (2019) 386–393; https://doi.org/10.1080/01480545.2018.145704910.1080/01480545.2018.145704929681198]Search in Google Scholar
[51. M. M. Smarr, M. Honda, K. Kannan, Z. Chen, S. Kim and G. M. B. Louis, Male urinary biomarkers of antimicrobial exposure and bi-directional associations with semen quality parameters, Reprod. Toxicol. 77 (2018) 103–108; https://doi.org/10.1016/j.reprotox.2018.02.00810.1016/j.reprotox.2018.02.008587814729474822]Search in Google Scholar
[52. M. M. Smarr, R. Sundaram, M. Honda, K. Kannan and G. M. B. Louis, Urinary concentrations of parabens and other antimicrobial chemicals and their association with couples’ fecundity, Environ. Health Perspect. 125 (2017) 730–736; https://doi.org/10.1289/EHP18910.1289/EHP189538197427286252]Search in Google Scholar
[53. L. Mínguez-Alarcón, Y.-H. Chiu, C. Messerlian, P. L. Williams, M. E. Sabatini, T. L. Toth, J. B. Ford, A. M. Calafat and R. Hauser – EARTH Study Team, Urinary paraben concentrations and in vitro fertilization outcomes among women from a fertility clinic, Fertil. Steril. 105 (2016) 714–721; https://doi.org/10.1016/j.fertnstert.2015.11.02110.1016/j.fertnstert.2015.11.021477971826654974]Search in Google Scholar
[54. The European Medicinal Agency (EMA), The Committee for Medicinal Products for Human Use and The Safety Working Party (SWP), Reflection Paper on the Use of Methyl- and Propylparaben as Excipients in Human Medicinal Products for Oral Use, London, October 2015; https://www.ema.europa.eu/en/documents/scientific-guideline/reflection-paper-use-methyl-propylparaben-excipients-human-medicinal-products-oral-use_en.pdf; last access date October 30, 2019.]Search in Google Scholar
[55. L. E. Dodge, K. E. Kelley, P. L. Williams, M. A. Williams, S. Hernandez-Diaz, S. A. Missmer and R. Hauser, Medications as a source of paraben exposure, Reprod. Toxicol. 52 (2015) 93–100; https://doi.org/10.1016/j.reprotox.2015.02.00210.1016/j.reprotox.2015.02.002442604325728410]Search in Google Scholar
[56. Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Fourth National Report on Human Exposure to Environmental Chemicals, CDC, Atlanta (GA), January 2019; https://www.cdc.gov/exposurereport/pdf/FourthReport_UpdatedTables_Volume1_Jan2019-508.pdf; last access date March 5, 2020.]Search in Google Scholar
[57. L. E. Dodge, J. W. Choi, K. E. Kelley, S. Herńandez-Diaz and R. Hauser, Medications as a potential source of exposure to parabens in the U.S. population, Environ. Res. 164 (2018) 580–584, https://doi.org/10.1016/j.envres.2018.03.03510.1016/j.envres.2018.03.035591794429625341]Search in Google Scholar
[58. A. Pop, T. Drugan, A. C. Gutleb, D. Lupu, J. Cherfan J, F. Loghin and B. Kiss, Estrogenic and anti-estrogenic activity of butylparaben, butylated hydroxyanisole, butylated hydroxytoluene and propyl gallate and their binary mixtures on two estrogen responsive cell lines (T47D-Kbluc, MCF-7), J. Appl. Toxicol.38 (2018) 944–957; https://doi.org/10.1002/jat.360110.1002/jat.360129460325]Search in Google Scholar
[59. The European Parliament and the Council of the European Union, Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products (Text with EEA relevance), OJ L 342 (2009) 59-209, November 2009; https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32009R1223&from=EN; last access date December 20, 2019]Search in Google Scholar
[60. The European Parliament and the Council of the European Union, Regulation (EC) No 1333/2008 of the European Parliament and of the Council of 16 December 2008 on food additives (Text with EEA relevance), OJ L 354 (2008) 16–33, December 2008; https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32008R1333&from=EN; last access date December 20, 2019.]Search in Google Scholar
[61. The European Parliament and the Council of the European Union, Regulation (EC) No 648/2004 of the European Parliament and of the Council of 31 March 2004 on detergents (Text with EEA relevance) OJ L 104 (2004) 1–35, March 2004; https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32004R0648; last access date December 20, 2019.]Search in Google Scholar
[62. European Commission, Report from The European Commission to The European Parliament and the Council, Review of Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products with regard to substances with endocrine-disrupting properties, November 2018; https://www.europarl.europa.eu/RegData/docs_autres_institutions/commission_europeenne/com/2018/0739/COM_COM(2018)0739_EN.pdf; last access date October 9, 2019.]Search in Google Scholar
[63. The European Food Safety Authority (EFSA), Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food on a request from the commission related to para hydroxybenzoates (E 214-219), Question number EFSA-Q-2004-063 (adopted on 13 July 2004), EFSA J. 83 (2004) 1–26; https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2004.8310.2903/j.efsa.2004.83]Search in Google Scholar
[64. L. Cuzzolin, Neonates exposed to excipients: concern about safety, J. Pediatr. Neonat. Individual Med. 7 (2018) e070112 (10 pages); https://doi.org/10.7363/070112]Search in Google Scholar
[65. The European Commission (EC), Scientific Committee on Consumer Safety (SCCS), Clarification on opinion SCCS/1348/10 in the light of the Danish clause of safeguard banning the use of parabens in cosmetic products intended for children under three years of age, SCCS, Luxembourg, October 2011; https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_069.pdf; last access date December 20, 2019.]Search in Google Scholar
[66. K. S. Valeur, H. Holst and K. Allegaert, Excipients in neonatal medicinal products: Never prescribed, commonly administered, Pharm. Med. 32 (2018) 251–258; https://doi.org/10.1007/s40290-018-0243-910.1007/s40290-018-0243-9610518130174435]Search in Google Scholar
[67. S. Kang, S. Kim, J. Park, H. J. Kim, J. Lee, G. Choi, S. Choi, S. Kim, S. Y. Kim, H. B. Moon, S. Kim, Y. L. Kho and K. Choi, Urinary paraben concentrations among pregnant women and their matching newborn infants of Korea, and the association with oxidative stress biomarkers, Sci. Total Environ. 461–462 (2013) 214–221, https://doi.org/10.1016/j.scitotenv.2013.04.09710.1016/j.scitotenv.2013.04.09723727995]Search in Google Scholar
[68. N.-Y. Park, Y. H. Cho, K. Choi, E.-H. Lee, Y. J. Kim, J. H. Kim and Y. Kho, Parabens in breast milk and possible sources of exposure among lactating women in Korea, Environ. Poll. 255 (2019) Article ID 113142; https://doi.org/10.1016/j.envpol.2019.11314210.1016/j.envpol.2019.11314231563777]Search in Google Scholar
[69. S. Yakkundi, H. Mulla, H. Pandya, M. A. Turner and J. McElnay, Quantitative analysis of methyl and propyl parabens in neonatal DBS using LC-MS/MS, Bioanalysis8 (2016) 1173–1182; https://doi.org/10.4155/bio-2016-002910.4155/bio-2016-002927212021]Search in Google Scholar
[70. M. A. Turner, J. C. Duncan, U. Shah, T. Metsvaht, H. Varendi, G. Nellis, I. Lutsar, S. Yakkundi, J. C. McElnay, H. Jandya, H. Mulla, P. Vaconsin, T. Storme, A. Rieutord and A. J. Nunn, Risk assessment of neonatal excipient exposure: lessons from food safety and other areas, Adv. Drug Deliv. Rev.73 (2014) 89–101; https://doi.org/10.1016/j.addr.2013.11.00310.1016/j.addr.2013.11.00324239480]Search in Google Scholar
[71. M. Bilal and H. M. N. Iqbal, An insight into toxicity and human-health-related adverse consequences of cosmeceuticals – A review, Sci. Total Environ.670 (2019) 555–568; https://doi.org/10.1016/j.scitotenv.2019.03.26110.1016/j.scitotenv.2019.03.26130909033]Search in Google Scholar
[72. C. L. Burnett, I. Boyer, W. F. Bergfeld, D. V. Belsito, R. A. Hill, C. D. Klaassen, D. C. Liebler, J. G. Marks, Jr., R. C. Shank, T. J. Slaga, P. W. Snyder, L. J. Gill and B. Heldreth, Amended safety assessment of methylisothiazolinone as used in cosmetics, Int. J. Toxicol. 38 (2019) 70–84; https://doi.org/10.1177/109158181983879210.1177/109158181983879231170842]Search in Google Scholar
[73. J. D. Lee, J. Y. Lee, S. J. Kwack, C. Y. Shin, H. J. Jang, H. Y. Kim, M. K. Kim, D. W. Seo, B. M. Lee and K. B. Kim, Risk assessment of triclosan, a cosmetic preservative, Toxicol. Res.35 (2019) 137–154; https://doi.org/10.5487/TR.2019.35.2.13710.5487/TR.2019.35.2.137646735531015896]Search in Google Scholar
[74. The SUBSPORTplus Portal, SUBSPORT project, SUBSPORT Specific Substances Alternatives Assessment – Parabens, March 2013; http://www.subsportplus.eu/wp-content/uploads/data/parabens.pdf; last access date December 20, 2019.]Search in Google Scholar
[75. M. Eisenhut, The toxicity of essential oils, Int. J. Infect. Dis. 11 (2007) 365; https://doi.org/10.1016/j.ijid.2006.07.00410.1016/j.ijid.2006.07.00417321181]Search in Google Scholar
[76. Council of Europe, European Directorate for the Quality of Medicines & HealthCare (EDQM), Guidance on essential oils in cosmetic products, 2016; https://zdravlje.gov.hr/UserDocsImages/2017%20dokumenti%20razni/Guidance%20on%20essential%20oils%20in%20cosmetic%20products_EDQM%202016.PDF; last access date December 22, 2019]Search in Google Scholar