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Acta Pharmaceutica
Volume 69 (2019): Issue 3 (September 2019)
Open Access
Metabolic stability and its role in the discovery of new chemical entities
Karolina Słoczyńska
Karolina Słoczyńska
,
Agnieszka Gunia-Krzyżak
Agnieszka Gunia-Krzyżak
,
Paulina Koczurkiewicz
Paulina Koczurkiewicz
,
Katarzyna Wójcik-Pszczoła
Katarzyna Wójcik-Pszczoła
,
Dorota Żelaszczyk
Dorota Żelaszczyk
,
Justyna Popiół
Justyna Popiół
and
Elżbieta Pękala
Elżbieta Pękala
| Jun 26, 2019
Acta Pharmaceutica
Volume 69 (2019): Issue 3 (September 2019)
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Published Online:
Jun 26, 2019
Page range:
345 - 361
Accepted:
Dec 29, 2018
DOI:
https://doi.org/10.2478/acph-2019-0024
Keywords
metabolic stability
,
biotransformation
,
intrinsic clearance
,
half-life
,
metabolites
,
new chemical entity
© 2019 Karolina Słoczyńska et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.