Antioxidative Activity and Inhibition of Key Enzymes Linked to Type-2 Diabetes (α-Glucosidase and α-Amylase) by Khaya Senegalensis

1. International Diabetes Federation: Diabetes Atlas 2011, 5th ed., International Diabetes Federation, Brussels 2011.Search in Google Scholar

2. K. Srinivasan, B. Viswanad, A. Lydia, C. L. Kaul and P. Ramarao, Combination of high-fat diet-fed and low-dose streptozotocin treated rat: A model for type 2 diabetes and pharmacological screening, Pharmacol. Res. 52 (2005) 313-320; DOI: 10.1016/j.phrs.2005.05.004.10.1016/j.phrs.2005.05.004Search in Google Scholar

3. D. Quilliot, E. Walter, J. P. Bonte, J. C. Fruchart, P. Duriez and O. Ziegler, Diabetes mellitus worsens antioxidant status in patients with chronic pancreatitis, Am. J. Clin. Nutr. 81 (2005) 1111-1117.10.1093/ajcn/81.5.1117Search in Google Scholar

4. N. F. Wiernsperger, Oxidative stress as a therapeutic target in diabetes: revisiting the controversy, Diabetes Metab. 29 (2003) 579-585; DOI: 10.1016/S1262-3636(07)70072-1.10.1016/S1262-3636(07)70072-1Search in Google Scholar

5. A. Ceriello, Oxidative stress and diabetes-associated complications, Endocr. Pract. 1 (2006) 60-62.10.4158/EP.12.S1.6016627383Search in Google Scholar

6. A. O. Ademiluyi and G. Oboh, Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (a-amylase and a-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro, Exp. Tox. Pathol. 65 (2013) 305-309; DOI: 10.1016/j.etp.2011.09.005.10.1016/j.etp.2011.09.00522005499Search in Google Scholar

7. Y. Kawamura-Konishi, N. Watanabe, M. Saito, N. Nakajima, T. Sakaki, T. Katayama and T. Enomoto, Isolation of a new phlorotannin, a potent inhibitor of carbohydrate-hydrolyzing enzymes, from the brown algae Sargassum patens, J. Agric. Food Chem. 60 (2012) 5565−5570; DOI: 10.1021/ jf300165j.Search in Google Scholar

8. T. Fujisawa, H. Ikegami, K. Inoue, Y. Kawabata and T. Ogihara, Effect of two a-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms, Metabolism 54 (2005) 387−390; DOI: 10.1016/j.metabol.2004.10.004.10.1016/j.metabol.2004.10.00415736118Search in Google Scholar

9. D. Neuser, A. Benson, A. Bruckner, R. B. Goldberg, B. J. Hoogwerf and D. Petzinna, Safety and tolerability of acarbose in the treatment of type 1 and type 2 diabetes mellitus, Clin. Drug Invest. 25 (2005) 579−587; DOI: 10.2165/00044011-200525090-00003.10.2165/00044011-200525090-0000317532702Search in Google Scholar

10. W. Benalla, S. Bellahcen and M. Bnouham, Antidiabetic medicinal plants as a source of a-glucosidase inhibitors, Curr. Diabetes Rev. 6 (2010) 247−254; DOI: 10.2174/157339910791658826.10.2174/15733991079165882620522017Search in Google Scholar

11. E. U. Etuk, S. O. Bello, S. A. Isezuo and B. J. Mohammed, Ethnobotanical survey of medicinal plants used for the treatment of diabetes mellitus in the north western region of Nigeria, Asian J. Exp. Biol. Sci. 1 (2010) 55-59.Search in Google Scholar

12. T. van Andel, B. Myren and S. van Onselen, Ghana’s herbal market, J. Ethnopharmacol. 140 (2012) 368-378; DOI: 10.1016/j.jep.2012.01.028.10.1016/j.jep.2012.01.02822306470Search in Google Scholar

13. O. T. Kolawole, S. O. Kolawole, A. A. Ayankunle and O. I. Olaniran, Anti-hyperglycemic effect of Khaya senegalensis stem bark aqueous extract in Wistar rats, Eur. J. Med. Plants 2 (2012) 66-73.10.9734/EJMP/2012/934Search in Google Scholar

14. I. Funke and M. F. Melzig, Traditionally used plants in diabetes therapy-phytotherapeutics as inhibitors of a-amylase activity, Rev. Bras. Farmacogn. 16 (2006) 1-5.10.1590/S0102-695X2006000100002Search in Google Scholar

15. S. McDonald, P. D. Prenzier, M. Autokiwich and K. Robards, Phenolics content and antioxidant activity of olive oil extracts, Food Chem. 73 (2001) 73-84; DOI: 10.1016/S0308-8146(00)00288-0.10.1016/S0308-8146(00)00288-0Search in Google Scholar

16. A. K. Tuba and I. Gulcin, Antioxidant and radical scavenging properties of curcumin, Chemico- Biol. Inter. 174 (2008) 27-37; DOI: 10.1016/j.cbi.2008.05.003.10.1016/j.cbi.2008.05.00318547552Search in Google Scholar

17. I. Hinneburg, H. J. Damien and R. Hiltunen, Antioxidant activities of extracts from selected culinary herbs and spices, Food Chem. 97 (2006) 122-129; DOI: 10.1016/j.foodchem.2005.03.028.10.1016/j.foodchem.2005.03.028Search in Google Scholar

18. A. G. Kurian, S. Suryanarayanan, A. Raman and J. Pidakalla, Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts, Chin. Med. 5 (2010) 1-7; DOI: 10.1186/1749-8546-3.Search in Google Scholar

19. L. J. Shai, P. Masoko, M. P. Mokgotho, S. R. Magano, A. M. Mogale, N. Boaduo and J. N. Eloff, Yeast alpha glucosidase inhibitory and antioxidant activities of six medicinal plants collected in Phalaborwa, South Africa, South Afr. J. Bot. 76 (2010) 465-470; DOI: 10.1016/j.sajb.2010.03.002.10.1016/j.sajb.2010.03.002Search in Google Scholar

20. Y. I. Kwon, E. Apostolidis, Y. C. Kim and K. Shetty, Health benefits of traditional corn, beans and pumpkin: in vitro studies for hyperglycemia and hypertension management, J. Med. Food. 10 (2007) 266-275; DOI: 10.1089/jmf.2006.234.10.1089/jmf.2006.23417651062Search in Google Scholar

21. W. Kang, Y. Song and X. Gu, a-glucosidase inhibitory in vitro and antidiabetic activity in vivo of Osmanthus fragrans, J. Med. Plants Res. 6 (2012) 2850-2856; DOI: 10.5897/JMPR11.1402.10.5897/JMPR11.1402Search in Google Scholar

22. O. Kamiyama, F. Sanae, K. Ikeda, Y. Higashi, Y. Minami, N. Asano, I. Adachi and A. Kato, In vitro inhibition of a-glucosidases and glycogen phosphorylase by catechin gallates in green tea, Food Chem. 122 (2010) 1061−1066; DOI: 10.1016/j.foodchem.2010.03.075.10.1016/j.foodchem.2010.03.075Search in Google Scholar

23. T. T. Mai, N. N. Thu, P. G. Tien and N. V. Chuyen, Alpha-glucosidase and antioxidant activities of Vietnamese edible plants and their relationships with polyphenol contents, J. Nutr. Sci. Vitaminol. 53 (2007) 267-276; DOI: 10.3177/jnsv.53.267.10.3177/jnsv.53.26717874833Search in Google Scholar

24. M. A. Ibrahim, A. B. Aliyu, A. Abusufiyanu, M. Bashir and A. B. Sallau, Inhibition of Naja nigricolis (Reinhardt) venom protease activity by Luffa egyptiaca (Mill) and Nicotiana rustica (Linn) extracts, Indian J. Exp. Biol. 49 (2011) 552-554.Search in Google Scholar

25. A. B. Sallau, G. C. Njoku, A. R. Olabisi, A. U. Wurochekke, A. A. Abdulkadir, S. Isah, M. S. Abubakar and S. Ibrahim, Effect of Guiera senegalensis leaf extract on some Echis carinatum venom enzymes, J. Med. Sci. 5 (2005) 280-283. 10.3923/jms.2005.280.283Search in Google Scholar