Resveratrol as a modulator of the gut-brain axis in irritable bowel syndrome

Resveratrol, a polyphenolic compound synthesized by plants, has garnered increasing attention in recent years for its potential pharmacological applications. Notably, it has been explored as a modulator of the gut-brain axis, particularly concerning irritable bowel syndrome (IBS). IBS is a life-quality impairing condition characterized by recurrent abdominal pain associated with defecation, as well as alterations in stool frequency or form. This review provides a comprehensive overview of the role of the gut-brain axis in IBS, with a specific focus on the potential of resveratrol as a modulator of this axis and its therapeutic implications for IBS management.