<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Glioblastoma is a highly aggressive and complex pathology that has garnered significant interest among researchers and clinicians due to its high mortality rates. This research article provides a systematic analysis of key aspects related to glioblastoma, offering comprehensive insights into its underlying complexities. The text explores the epidemiological patterns, etiological factors, and genetic and molecular foundations underlying the development of GBM. It also examines the interplay between the immune system and the tumor, identifying specific immune markers with potential diagnostic value. The article describes the complex processes involved in tumor growth, including its interaction with surrounding tissues, the development of the tumor microenvironment, and the role of stem cells. It also provides an analysis of current treatment options and the challenges they face, particularly in relation to tumor resistance. The article concludes with a thorough examination of the changing landscape of diagnostic and therapeutic approaches. It highlights notable recent research findings and provides insight into potential advancements that could shape the future of medical interventions for glioblastoma.</p>
</abstract>

Glioblastoma is a highly aggressive and complex pathology that has garnered significant interest among researchers and clinicians due to its high mortality rates. This research article provides a systematic analysis of key aspects related to glioblastoma, offering comprehensive insights into its underlying complexities. The text explores the epidemiological patterns, etiological factors, and genetic and molecular foundations underlying the development of GBM. It also examines the interplay between the immune system and the tumor, identifying specific immune markers with potential diagnostic value. The article describes the complex processes involved in tumor growth, including its interaction with surrounding tissues, the development of the tumor microenvironment, and the role of stem cells. It also provides an analysis of current treatment options and the challenges they face, particularly in relation to tumor resistance. The article concludes with a thorough examination of the changing landscape of diagnostic and therapeutic approaches. It highlights notable recent research findings and provides insight into potential advancements that could shape the future of medical interventions for glioblastoma.

Glioblastoma: A molecular insight into current discoveries and treatment directions

Medical Journal of Cell Biology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Glioblastoma is a highly aggressive and complex pathology that has garnered significant interest among researchers and clinicians due to its high mortality...

Glioblastoma: A molecular insight into current discoveries and treatment directions

Published Online: Jul 05, 2024

Page range: 1 - 20

Received: Feb 15, 2024

Accepted: Apr 10, 2024

DOI: https://doi.org/10.2478/acb-2024-0001

Keywords
glioblastoma, GBM, IDH, EGFR, GSC, TME

© 2024 Wiktor Świątek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Glioblastoma: A molecular insight into current discoveries and treatment directions

Published Online: Jul 05, 2024

Page range: 1 - 20

Received: Feb 15, 2024

Accepted: Apr 10, 2024

DOI: https://doi.org/10.2478/acb-2024-0001

Keywordsglioblastoma, GBM, IDH, EGFR, GSC, TME

© 2024 Wiktor Świątek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
glioblastoma, GBM, IDH, EGFR, GSC, TME