<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and highly accurate test results without involving complicated procedures. This has been accomplished by introducing rapid bioanalytical tools or biosensors such as lateral flow assays (LFAs). The production cost of these tools is very low, allowing developing countries with limited resources to utilize them or produce them on their own. Thus, their use has grown in various fields in recent years. More importantly, LFAs have created the possibility for a new era of incorporating nanotechnology in disease diagnosis and have already attained significant commercial success worldwide, making POCT an essential approach not just for now but also for the future. In this review, we have provided an overview of POCT and its evolution into the most promising rapid diagnostic approach. We also elaborate on LFAs with a special focus on nucleic acid LFAs.</p>
</abstract>

The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and highly accurate test results without involving complicated procedures. This has been accomplished by introducing rapid bioanalytical tools or biosensors such as lateral flow assays (LFAs). The production cost of these tools is very low, allowing developing countries with limited resources to utilize them or produce them on their own. Thus, their use has grown in various fields in recent years. More importantly, LFAs have created the possibility for a new era of incorporating nanotechnology in disease diagnosis and have already attained significant commercial success worldwide, making POCT an essential approach not just for now but also for the future. In this review, we have provided an overview of POCT and its evolution into the most promising rapid diagnostic approach. We also elaborate on LFAs with a special focus on nucleic acid LFAs.

Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases

Department of Biomedical Science, Faculty of Medicine and Health Sciences

Department of Medical Microbiology, Faculty of Medicine and Health Sciences

Centre for Chemical Biology and Therapeutics

Malaysian Research Institute on Ageing (MyAgeing)

Asian Biomedicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases...

Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases

Article Category: Review

Published Online: Dec 28, 2023

Page range: 250 - 266

DOI: https://doi.org/10.2478/abm-2023-0068

Keywords
aptamer, biosensor, lateral flow assay, nucleic acid, point-of-care testin

© 2023 Kumaravel Vealan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases

Article Category: Review

Published Online: Dec 28, 2023

Page range: 250 - 266

DOI: https://doi.org/10.2478/abm-2023-0068

Keywordsaptamer, biosensor, lateral flow assay, nucleic acid, point-of-care testin

© 2023 Kumaravel Vealan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
aptamer, biosensor, lateral flow assay, nucleic acid, point-of-care testin