Influence of education training in patients with type 2 diabetes in the improvement of lifestyle and biochemical characteristics: a randomized controlled trial

Clinical and biochemical characteristics of the participants by groups at the time of inclusion in the study (n = 100)_

Clinical and biochemical characteristics	Groups (M ± SD)		P
	Intervention	Control
Systolic arterial pressure (mmHg)	129.30 ± 11.80	131.50 ± 7.50	0.111*
Diastolic arterial pressure (mmHg)	74.50 ± 8.40	74.40 ± 7.10	0.678*
HbA1c (%)	7.03 ± 0.25	6.90 ± 0.34	0.118*
BMI (kg/m2)	26.70 ± 1.80	26.90 ± 1.40	0.361*
Cholesterol (mg/dl)	218.37 ± 43.50	213.33 ± 43.20	0.412*
Triglycerides (mg/dl)	228.70 ± 99.20	211.12 ± 75.50	0.100*

The distribution of participants by level of reduction of HbA1c value and study groups_

Group	Reduction of HbA1c <15%	Reduction of HbA1c = 15%
Intervention	57%	43%
Control	98%	2%

Effects of education in lowering HbA1c by 15%_

Group	OR*	95% Coefficient interval	OR**	95% Coefficient interval	OR***	95% Coefficient interval
Intervention	36.9†	8.7–161.9	37.6†	8.7–162	37.9†	8.7–162
Control^	1		1		1

Values of clinical and biochemical characteristics of the participants at the end of the study_

Items	Intervention group			Control group
	Baseline	After 6 months	P	Baseline	After 6 months	P
HbA1c (%)	7.02	6.23	0.001*	6.90	6.81	0.001*
Systolic arterial pressure (mmHg)	129.38	128.54	0.001*	131.50	130.50	0.020*
Diastolic arterial pressure (mmHg)	74.57	74.65	0.535	74.40	74.46	0.695
Cholesterol (mg/dl)	218.37	207.18	0.001*	213.30	210.20	0.001*
Triglycerides (mg/dl)	228.57	197.70	0.001*	210.70	208.60	0.170
BMI (kg/m2)	26.65	25.32	0.001*	26.80	26.90	0.678

Demographic characteristics of participants (n = 200)_

Items	n (%)	M ± SD	95% interval Coefficient	Age range
Gender
Male	104 (52)
Female	96 (48)
Age (years)		54.9 ± 8.7	53.7–56.2	36–80

Comparison of the mean differences in values of the clinical and biochemical characteristics of the participants before and after the intervention_

The mean differences in values of the clinical and biochemical characteristics	Group (mean)		P
	Intervention	Control
BMI (kg/m2)	-1.3203	0.0090	0.001*
HbA1c (%)	-0.7906	-0.0854	0.001*
Triglycerides (mg/dl)	-31.5025	-2.1054	0.001*
Cholesterol (mg/dl)	-11.1878	-3.0894	0.001*
Systolic arterial pressure (mmHg)	0.0800	0.0600	0.715
Diastolic arterial pressure (mmHg)	-0.8400	-1.0200	0.914

Clinical and biochemical characteristics of the participants by groups after intervention_

Clinical and biochemical characteristics	Intervention group	Control group	P
HbA1c (%)	6.20	6.80	0.001*
Systolic arterial pressure (mmHg)	128.50	130.53	0.199
Diastolic arterial pressure (mmHg)	74.60	74.50	0.860
Cholesterol (mg/dl)	207.18	210.20	0.188
Triglycerides (mg/dl)	197.07	208.60	0.187
BMI (kg/m2)	25.30	26.90	0.001*