Apomorphine subcutaneous titration in Parkinson’s disease - the effectiveness and safety of apomorphine challenges: A Literature Review

Article Number	Type of Bias Found
(Pfeiffer, Gutmann et al. 2007) RCT	Measurement bias, Funding bias
(Pahwa, Koller et al. 2007) RCT	Sampling bias, Participant/ rater bias, Funding bias
(Katzenschlager, Poewe et al. 2018) RCT	Funding bias
(Ostergaard, Werdelin et al. 1995) RCT	Sample bias, Blinding bias
(Ondo, Hunter et al. 2012) Cohort	blinding, sample bias, reporter, patient bias,
(Colzi, Turner et al. 1998) Cohort	Sample, Measurement, Unblinded, No randomisation
(Sesar, Fernández-Pajarín et al. 2017) Cohort	Attrition bias, Measurement bias, Unblinded, No randomisation
(Isaacson, Lew et al. 2016) Cohort	Funding, Unblinded, No randomisation
(Pietz, Hagell et al. 1998) Cohort	Measurement bias, Sample bias, Unblinded, No randomisation
(Muguet, Broussolle et al. 1995)	Measurement, reporter, search strategy, design
(Setter 2008)	Measurement, reporter, search strategy design
(Perez-Lloret and Rascol 2010)	Measurement, reporter, search strategy design
(Factor 2004)	Measurement, reporter, search strategy design
(van Laar and Borgemeester 2016)	Measurement, reporter, search strategy design
(Bhidayasiri, Garcia Ruiz et al. 2016)	Not systematic, excluded studies or inclusion criteria, did not explain risks of bias or study design, nil meta-analysis, reporter, publication, selection bias, omitted bias, statistical and observer
(Deleu, Hanssens et al. 2004)	Rater bias,
(Clarke, Davies et al. 2000)	Reporter bias - unable to tell if reviewed independently.
(Tomlinson, Stowe et al. 2010)	Rater bias,
(Bhidayasiri, Chaudhuri et al. 2015)	Rater, measurement, reporter, search strategy, design
(Price, Martin et al. 2016)	Nil blinding, selection bias, reporter bias, study design, no control of confounders, nil blinding, nil standardised collection tools, nil statistical analysis
(Albanese, Bonuccelli et al. 2001)	Not systematic, no thorough literature search methods mentioned, did not list excluded studies or inclusion criteria, did not explain risks of bias or study design, nil metanalysis, high risk of reporter, publication, selection bias, omitted bias,
(Trenkwalder, Chaudhuri et al. 2015)	Rater, reporter, funded, measurement, sample, design, blinding,
(Jenner and Katzenschlager 2016)	Rater, measurement, reporter, sample, design, blinding, funding

Language:: English

Publication timeframe:: 2 times per year
Journal Subjects:: Medicine, Basic Medical Science, Basic Medical Science, other

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Apomorphine subcutaneous titration in Parkinson’s disease - the effectiveness and safety of apomorphine challenges: A Literature Review

Amy E Jones

Elise M Tune

Published Online: May 30, 2023

Page range: 39 - 47

DOI: https://doi.org/10.21307/ajon-2023-005

Keywords

© 2023 Amy E Jones et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

j_ajon-2023-005_utab_001