The pattern of renal artery Doppler indices in patients with sickle cell disease
Vivek Patre
Orcid profile and Nobal Chandrakar
Orcid profile 
Article Category: Research paper
Published Online: Nov 08, 2024
Page range: 1 - 4
Received: Aug 16, 2023
Accepted: Dec 27, 2023
DOI: https://doi.org/10.15557/jou.2024.0017
Keywords
© 2024 Vivek Patre et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Aim
To evaluate the pattern of renal artery Doppler indices in patients with sickle cell disease who do not have laboratory evidence of renal impairment.
Material and methods
A case-control study was carried out after enrolling 50 patients with sickle cell disease (HbSS phenotype) (sickle cell disease group) and 50 control subjects (control group). All the participants underwent ultrasound and color Doppler examination, and the pulsatility index and resistive index values of the main renal artery, segmental artery, and interlobar artery in both kidneys were recorded and compared.
Results
The Doppler measurements of the main renal artery, segmental artery, and interlobar artery were compared between the control and sickle cell disease groups. It was found that both pulsatility index and resistive index were significantly higher in the sickle cell disease group, as compared to the control group, for the main renal artery, segmental artery, and interlobar artery (
Conclusions
Resistive index and pulsatility index values in renal Doppler sonography can serve as early radiologic predictors of renal vascular changes in sickle cell disease patients who do not have laboratory evidence of renal impairment.