<abstract xmlns="http://www.w3.org/1999/xhtml">Knee osteoarthritis is a degenerative joint disease characterized by cartilage degeneration and hypertrophic lesions of the epiphyseal bone. It is a disabling condition that causes difficulties of locomotion and severe complications in case of inappropriate treatment. There is growing evidence proving the beneficial effects of using platelet-rich plasma (PRP) in the treatment of knee osteoarthritis.<italic>The aim</italic> of the present paper is to review the recent scientific literature on the treatment of knee osteoarthritis with platelet-rich plasma presenting the current opinion on this subject.<italic>Methods</italic>: We analys several studies about PRP who were identified using online databases: EBSCO, ScienceDirect, Scopus and PubMed.<italic>Results:</italic> After the primary analysis we selected a total of 23 relevant studies. The analysis focused on different PRP administration techniques and methods used in knee osteoarthritis.<italic>Conclusions:</italic> PRP is most widely used in incipient and moderate symptomatic knee osteoarthritis. Most studies show a significant decrease in pain and significant improvement in joint functionality. These results were mostly obtained after a short follow-up period (6 months-1 year) and also this treatment has a small number of side effects.</abstract>

Knee osteoarthritis is a degenerative joint disease characterized by cartilage degeneration and hypertrophic lesions of the epiphyseal bone. It is a disabling condition that causes difficulties of locomotion and severe complications in case of inappropriate treatment. There is growing evidence proving the beneficial effects of using platelet-rich plasma (PRP) in the treatment of knee osteoarthritis.The aim of the present paper is to review the recent scientific literature on the treatment of knee osteoarthritis with platelet-rich plasma presenting the current opinion on this subject.Methods: We analys several studies about PRP who were identified using online databases: EBSCO, ScienceDirect, Scopus and PubMed.Results: After the primary analysis we selected a total of 23 relevant studies. The analysis focused on different PRP administration techniques and methods used in knee osteoarthritis.Conclusions: PRP is most widely used in incipient and moderate symptomatic knee osteoarthritis. Most studies show a significant decrease in pain and significant improvement in joint functionality. These results were mostly obtained after a short follow-up period (6 months-1 year) and also this treatment has a small number of side effects.

Platelet-rich plasma intra-articular injections as an alternative treatment for knee osteoarthritis: a systematic review

Timisoara Physical Education and Rehabilitation Journal

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Knee osteoarthritis is a degenerative joint disease characterized by cartilage degeneration and hypertrophic lesions of the epiphyseal bone. It is a disabling...

Platelet-rich plasma intra-articular injections as an alternative treatment for knee osteoarthritis: a systematic review

Published Online: Mar 28, 2019

Page range: 46 - 51

DOI: https://doi.org/10.1515/tperj-2017-0015

Keywords
platelet-rich plasma (PRP), knee osteoarthritis, pain, function, range of motion

© 2017 Elena Sîrbu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Platelet-rich plasma intra-articular injections as an alternative treatment for knee osteoarthritis: a systematic review

Published Online: Mar 28, 2019

Page range: 46 - 51

DOI: https://doi.org/10.1515/tperj-2017-0015

Keywordsplatelet-rich plasma (PRP), knee osteoarthritis, pain, function, range of motion

© 2017 Elena Sîrbu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
platelet-rich plasma (PRP), knee osteoarthritis, pain, function, range of motion