Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90JemalABrayFCenterMMFerlayJWardEFormanDGlobal cancer statisticsCA Cancer J Clin201161699010.3322/caac.2010721296855Search in Google Scholar
Winder T, Wilson PM, Yang D, Zhang W, Ning Y, Power DG, et al. An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence. Pharmacogenomics J 2013; 13: 342-8WinderTWilsonPMYangDZhangWNingYPowerDGet alAn individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrencePharmacogenomics J20131334234810.1038/tpj.2012.1122491017Search in Google Scholar
Hudler P, Repse S, Juvan R, Komel R. A genomic approach to investigate expression profiles in Slovenian patients with gastric cancer. Oncol Lett 2011; 2: 1003-4HudlerPRepseSJuvanRKomelRA genomic approach to investigate expression profiles in Slovenian patients with gastric cancerOncol Lett201121003100410.3892/ol.2011.362340802522866164Search in Google Scholar
Ottini L, Falchetti M, Lupi R, Rizzolo P, Agnese V, Colucci G, et al. Patterns of genomic instability in gastric cancer: clinical implications and perspectives. Ann Oncol 2006; 17: vii97-vii102OttiniLFalchettiMLupiRRizzoloPAgneseVColucciGet alPatterns of genomic instability in gastric cancer: clinical implications and perspectivesAnn Oncol200617vii97vii10210.1093/annonc/mdl96016760303Search in Google Scholar
Resende C, Ristimaki A, Machado JC. Genetic and epigenetic alteration in gastric carcinogenesis. Helicobacter 2010; 15(Suppl 1): 34-9ResendeCRistimakiAMachadoJCGenetic and epigenetic alteration in gastric carcinogenesisHelicobacter201015(Suppl 1)343910.1111/j.1523-5378.2010.00782.x21054651Search in Google Scholar
Tahara E. Abnormal growth factor/cytokine network in gastric cancer. Cancer Microenviron 2008; 1: 85-91TaharaEAbnormal growth factor/cytokine network in gastric cancerCancer Microenviron20081859110.1007/s12307-008-0008-1265435919308687Search in Google Scholar
Chen J, Liu NN, Li JQ, Yang L, Zeng Y, Zhao XM, et al. Association between ITGA2 C807T polymorphism and gastric cancer risk. World J Gastroenterol2011; 17: 2860-6ChenJLiuNNLiJQYangLZengYZhaoXMet alAssociation between ITGA2 C807T polymorphism and gastric cancer riskWorld J Gastroenterol20111728602866Search in Google Scholar
Gonzalez CA, Agudo A. Carcinogenesis, prevention and early detection of gastric cancer: where we are and where we should go. Int J Cancer 2012; 130: 745-53GonzalezCAAgudoACarcinogenesis, prevention and early detection of gastric cancer: where we are and where we should goInt J Cancer201213074575310.1002/ijc.2643021918974Search in Google Scholar
Milne AN, Carneiro F, O’Morain C, Offerhaus GJ. Nature meets nurture: molecular genetics of gastric cancer. Hum Genet 2009; 126: 615-28MilneANCarneiroFO’morainCOfferhausGJNature meets nurture: molecular genetics of gastric cancerHum Genet200912661562810.1007/s00439-009-0722-x277114019657673Search in Google Scholar
Pinheiro DdR, Ferreira WA, Barros MB, Araujo MD, Rodrigues-Antunes S, Borges Bdo N. Perspectives on new biomarkers in gastric cancer: diagnostic and prognostic applications. World J Gastroenterol 2014; 20: 11574-85PinheiroDdRFerreiraWABarrosMBAraujoMDRodrigues-antunesSBorges bdoNPerspectives on new biomarkers in gastric cancer: diagnostic and prognostic applicationsWorld J Gastroenterol201420115741158510.3748/wjg.v20.i33.11574415535125206265Search in Google Scholar
Tan P. Germline polymorphisms as modulators of cancer phenotypes. BMC Med 2008; 6: 27TanPGermline polymorphisms as modulators of cancer phenotypesBMC Med200862710.1186/1741-7015-6-27254303218778478Search in Google Scholar
Bass AJ, Thorsson V, Shmulevich I, Reynolds SM, Miller M, Bernard B, et al. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014; 513: 202-9BassAJThorssonVShmulevichIReynoldsSMMillerMBernardBet alComprehensive molecular characterization of gastric adenocarcinomaNature201451320220910.1038/nature13480Search in Google Scholar
Grabsch HI, Askham JM, Morrison EE, Pomjanski N, Lickvers K, Parsons WJ, et al. Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability. J Pathol 2004; 202: 208-14GrabschHIAskhamJMMorrisonEEPomjanskiNLickversKParsonsWJet alExpression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instabilityJ Pathol200420220821410.1002/path.1499Search in Google Scholar
Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, et al. High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer. Cancer Sci 2010; 101: 639-45AndoKKakejiYKitaoHIimoriMZhaoYYoshidaRet alHigh expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancerCancer Sci201010163964510.1111/j.1349-7006.2009.01457.xSearch in Google Scholar
Lo YL, Yu JC, Chen ST, Hsu GC, Mau YC, Yang SL, et al. Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibility. Carcinogenesis 2007; 28: 1079-86LoYLYuJCChenSTHsuGCMauYCYangSLet alBreast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibilityCarcinogenesis2007281079108610.1093/carcin/bgl256Search in Google Scholar
Castro dIP, Carcer dG, Malumbres M. A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy. Carcinogenesis 2007; 28: 899-912CastrodIPCarcerdGMalumbresMA census of mitotic cancer genes: New insights into tumor cell biology and cancer therapyCarcinogenesis20072889991210.1093/carcin/bgm019Search in Google Scholar
Yuan B, Xu Y, Woo JH, Wang Y, Bae YK, Yoon DS, et al. Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability. Clin Cancer Res 2006; 12: 405-10YuanBXuYWooJHWangYBaeYKYoonDSet alIncreased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instabilityClin Cancer Res20061240541010.1158/1078-0432.CCR-05-0903Search in Google Scholar
Couch FJ, Wang X, Bamlet WR, de Andrade M, Petersen GM, McWilliams RR. Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Cancer Epidemiol Biomarkers Prev 2010; 19: 251-7CouchFJWangXBamletWRde andradeMPetersenGMMcWilliamsRRAssociation of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcomeCancer Epidemiol Biomarkers Prev20101925125710.1158/1055-9965.EPI-09-0629Search in Google Scholar
Wang P, Wang Y, Yan H, Xie Q, Zhao L, Xu S, et al. Genetic variation in the major mitotic checkpoint genes and risk of breast cancer: a multigenic study on cancer susceptibility. Tumour Biol 2014; 35: 6701-5WangPWangYYanHXieQZhaoLXuSet alGenetic variation in the major mitotic checkpoint genes and risk of breast cancer: a multigenic study on cancer susceptibilityTumour Biol2014356701670510.1007/s13277-014-1906-0Search in Google Scholar
Wang X, Fredericksen ZS, Vierkant RA, Kosel ML, Pankratz VS, Cerhan JR, et al. Association of genetic variation in mitotic kinases with breast cancer risk. Breast Cancer Res Treat 2010; 119: 453-62WangXFredericksenZSVierkantRAKoselMLPankratzVSCerhanJRet alAssociation of genetic variation in mitotic kinases with breast cancer riskBreast Cancer Res Treat201011945346210.1007/s10549-009-0404-3Search in Google Scholar
Duesberg P, Rasnick D. Aneuploidy, the somatic mutation that makes cancer a species of its own. CellMotil Cytoskeleton 2000; 47: 81-107DuesbergPRasnickDAneuploidy, the somatic mutation that makes cancer a species of its ownCellMotil Cytoskeleton2000478110710.1002/1097-0169(200010)47:2<81::AID-CM1>3.0.CO;2-#Search in Google Scholar
Frank SA. Genetic predisposition to cancer - insights from population genetics. Nat Rev Genet 2004; 5: 764-72FrankSAGenetic predisposition to cancer - insights from population geneticsNat Rev Genet2004576477210.1038/nrg145015510167Search in Google Scholar
Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, Cota E, Simpson PJ, Chirgadze DY, et al. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding site. Structure 2011; 19: 1691-700Bolanos-garciaVMLischettiTMatak-vinkovicDCotaESimpsonPJChirgadzeDYet alStructure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding siteStructure2011191691170010.1016/j.str.2011.09.017326704022000412Search in Google Scholar
Chao WC, Kulkarni K, Zhang Z, Kong EH, Barford D. Structure of the mitotic checkpoint complex. Nature 2012; 484: 208-13ChaoWCKulkarniKZhangZKongEHBarfordDStructure of the mitotic checkpoint complexNature201248420821310.1038/nature1089622437499Search in Google Scholar
Tian W, Li B, Warrington R, Tomchick DR, Yu H, Luo X. Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc Natl Acad Sci U S A2012; 109: 18419-24TianWLiBWarringtonRTomchickDRYuHLuoXStructural analysis of human Cdc20 supports multisite degron recognition by APC/CProc Natl Acad Sci U S A20121091841918412410.1073/pnas.1213438109349491023091007Search in Google Scholar
Bolanos-Garcia VM, Blundell TL. BUB1 and BUBR1: multifaceted kinases of the cell cycle. Trends Biochem Sci 2011; 36: 141-50Bolanos-garciaVMBlundellTLBUB1 and BUBR1: multifaceted kinases of the cell cycleTrends Biochem Sci20113614115010.1016/j.tibs.2010.08.004306198420888775Search in Google Scholar
Kagami Y, Nihira K, Wada S, Ono M, Honda M, Yoshida K. Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis. J Cell Biol 2014; 205: 781-90KagamiYNihiraKWadaSOnoMHondaMYoshidaKMps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosisJ Cell Biol201420578179010.1083/jcb.201308172406814024934155Search in Google Scholar
Santaguida S, Tighe A, D’Alise AM, Taylor SS, Musacchio A. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol 2010; 190: 73-87antaguidaSTigheAD’aliseAMTaylorSSMusacchioADissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversineJ Cell Biol2010190738710.1083/jcb.201001036291165720624901Search in Google Scholar
Lee S, Thebault P, Freschi L, Beaufils S, Blundell TL, Landry CR, et al. Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases. J Biol Chem 2012; 287: 5988-6001LeeSThebaultPFreschiLBeaufilsSBlundellTLLandryCRet alCharacterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinasesJ Biol Chem20122875988600110.1074/jbc.M111.307355328536622187426Search in Google Scholar
Hewitt L, Tighe A, Santaguida S, White AM, Jones CD, Musacchio A, et al. Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. J Cell Biol 2010; 190: 25-34HewittLTigheASantaguidaSWhiteAMJonesCDMusacchioAet alSustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complexJ Cell Biol2010190253410.1083/jcb.201002133291165920624899Search in Google Scholar
Rodriguez S, Gaunt TR, Day IN. Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies. Am J Epidemiol2009; 169: 505-14RodriguezSGauntTRDayINHardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studiesAm J Epidemiol200916950551410.1093/aje/kwn359264016319126586Search in Google Scholar
Farre D, Roset R, Huerta M, Adsuara JE, Rosello L, Alba MM, et al. Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN. Nucleic Acids Res 2003; 31: 3651-3FarreDRosetRHuertaMAdsuaraJERoselloLAlbaMMet alIdentification of patterns in biological sequences at the ALGGEN server: PROMO and MALGENNucleic Acids Res2003313651365310.1093/nar/gkg60516901112824386Search in Google Scholar
Messeguer X, Escudero R, Farre D, Nunez O, Martinez J, Alba MM. PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 2002; 18: 333-4MesseguerXEscuderoRFarreDNunezOMartinezJAlbaMMPROMO: detection of known transcription regulatory elements using species-tailored searchesBioinformatics20021833333410.1093/bioinformatics/18.2.33311847087Search in Google Scholar
Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, et al. An integrated map of genetic variation from 1,092 human genomes. Nature 2012; 491: 56-65AbecasisGRAutonABrooksLDDepristoMADurbinRMHandsakerREet alAn integrated map of genetic variation from 1,092 human genomesNature2012491566510.1038/nature11632349806623128226Search in Google Scholar
Cui Y, Cheng X, Zhang C, Zhang Y, Li S, Wang C, et al. Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases. J Biol Chem 2010; 285: 32988-98CuiYChengXZhangCZhangYLiSWangCet alDegradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligasesJ Biol Chem2010285329883299810.1074/jbc.M110.140905296333620729194Search in Google Scholar
Sun T, Yang X, Wang W, Zhang X, Xu Q, Zhu S, et al. Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment. J Biol Chem 2010; 285: 38730-9SunTYangXWangWZhangXXuQZhuSet alCellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitmentJ Biol Chem2010285387303873910.1074/jbc.M110.177642299230620884615Search in Google Scholar
Kaistha BP, Honstein T, Muller V, Bielak S, Sauer M, Kreider R, et al. Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells. Br J Cancer 2014; 111: 1780-7KaisthaBPHonsteinTMullerVBielakSSauerMKreiderRet alKey role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cellsBr J Cancer20141111780178710.1038/bjc.2014.460445372325137017Search in Google Scholar
Ling Y, Zhang X, Bai Y, Li P, Wei C, Song T, et al. Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy. Biochem Biophys Res Commun 2014; 450: 1690-5LingYZhangXBaiYLiPWeiCSongTet alOverexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidyBiochem Biophys Res Commun20144501690169510.1016/j.bbrc.2014.07.07125063032Search in Google Scholar
Rio Frio T, Lavoie J, Hamel N, Geyer FC, Kushner YB, Novak DJ, et al. Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia. N Engl J Med 2010; 363: 2628-37Rio frioTLavoieJHamelNGeyerFCKushnerYBNovakDJet alHomozygous BUB1B mutation and susceptibility to gastrointestinal neoplasiaN Engl J Med20103632628263710.1056/NEJMoa100656521190457Search in Google Scholar
Grabsch H, Takeno S, Parsons WJ, Pomjanski N, Boecking A, Gabbert HE, et al. Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation. J Pathol 2003; 200: 16-22GrabschHTakenoSParsonsWJPomjanskiNBoeckingAGabbertHEet alOverexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferationJ Pathol2003200162210.1002/path.132412692836Search in Google Scholar
Enjoji M, lida S, Sugita H, Ishikawa T, Uetake H, Inokuchi M, et al. BubR1 and AURKB overexpression are associated with a favorable prognosis in gastric cancer. Mol Med Report 2009; 2: 589-96EnjojiMlidaSSugitaHIshikawaTUetakeHInokuchiMet alBubR1 and AURKB overexpression are associated with a favorable prognosis in gastric cancerMol Med Report20092589596Search in Google Scholar
Bohers E, Sarafan-Vasseur N, Drouet A, Paresy M, Latouche JB, Flaman JM, et al. Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy. Hum Genet 2008; 124: 473-8BohersESarafan-vasseurNDrouetAParesyMLatoucheJBFlamanJMet alGradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidyHum Genet200812447347810.1007/s00439-008-0572-y18932004Search in Google Scholar
D’Arcy S, Davies OR, Blundell TL, Bolanos-Garcia VM. Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition. J Biol Chem 2010; 285: 14764-76D’arcySDaviesORBlundellTLBolanos-garciaVMDefining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibitionJ Biol Chem2010285147641477610.1074/jbc.M109.082016286323920220147Search in Google Scholar
