<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Objectives: Assessment of autoimmune cause hypothyroidism and dyslipidemia involvement in the apparition of major vascular complications. Methods: A total of 152 patients were investigated appreciating in comparison to a healthy control lot the hormone serum level, the presence of antimicrosomal thyroid antibodies and the serum levels of lipids. Atherogenic index and coronarian risk were calculated and correlated with the incidence of coronarian and cerebral vascular accidents. Results: Among the patients with goiter it was noted a high incidence of a subclinical hypothyroidism (31,58%). Thyroid autoimmunity was involved in 94,4% of the patients with clinical hypothyroidism, in 93,7 % with subclinical hypothyroidism and 100% in the patients with thyrotoxicosis. Low serum level of HDL-cholesterol was identified in 66,6% of patients with clinical hypothyroidism and 64,5% patients with subclinical hypothyroidism. The assessment of atherogenic index and coronarian risk was significantly higher (p&lt;0,01) in patients with hypothyroidism in comparison to healthy control subjects. The incidence of vascular accidents was significantly higher (p&lt;0,01) among the hypothyroid patients ( 19,7%/ 10,8%), of masculine gender (12,7%) where the main cause of hypothyroidism was autoimmunity. Conclusions: The atherogenic index and coronarian risk were higher in patients with hypothyroidism associated to thyroid autoimmunity resulting in an increased probability in producing vascular accidents </p></abstract>

Objectives: Assessment of autoimmune cause hypothyroidism and dyslipidemia involvement in the apparition of major vascular complications. Methods: A total of 152 patients were investigated appreciating in comparison to a healthy control lot the hormone serum level, the presence of antimicrosomal thyroid antibodies and the serum levels of lipids. Atherogenic index and coronarian risk were calculated and correlated with the incidence of coronarian and cerebral vascular accidents. Results: Among the patients with goiter it was noted a high incidence of a subclinical hypothyroidism (31,58%). Thyroid autoimmunity was involved in 94,4% of the patients with clinical hypothyroidism, in 93,7 % with subclinical hypothyroidism and 100% in the patients with thyrotoxicosis. Low serum level of HDL-cholesterol was identified in 66,6% of patients with clinical hypothyroidism and 64,5% patients with subclinical hypothyroidism. The assessment of atherogenic index and coronarian risk was significantly higher (p<0,01) in patients with hypothyroidism in comparison to healthy control subjects. The incidence of vascular accidents was significantly higher (p<0,01) among the hypothyroid patients ( 19,7%/ 10,8%), of masculine gender (12,7%) where the main cause of hypothyroidism was autoimmunity. Conclusions: The atherogenic index and coronarian risk were higher in patients with hypothyroidism associated to thyroid autoimmunity resulting in an increased probability in producing vascular accidents

Atherogenic index and coronarian risk – comparative assessment regarding the particularities of chronic autoimmune thyroiditis presence

Department of Endocrinology, Faculty of Medicine, “Ovidius” University Constanta

Department of Cardiology, Faculty of Medicine, “Ovidius” University Constanta

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Objectives: Assessment of autoimmune cause hypothyroidism and dyslipidemia involvement in the apparition of major vascular complications. Methods: A total of...

Atherogenic index and coronarian risk – comparative assessment regarding the particularities of chronic autoimmune thyroiditis presence

Published Online: Aug 25, 2015

Page range: 146 - 150

DOI: https://doi.org/10.1515/arsm-2015-0037

Keywords
hypothyroidism, dyslipidemia, atherogenic index, coronarian risk, antimicrosomal thyroid antibodies

© by Mihaela Seceleanu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Atherogenic index and coronarian risk – comparative assessment regarding the particularities of chronic autoimmune thyroiditis presence

Published Online: Aug 25, 2015

Page range: 146 - 150

DOI: https://doi.org/10.1515/arsm-2015-0037

Keywordshypothyroidism, dyslipidemia, atherogenic index, coronarian risk, antimicrosomal thyroid antibodies

© by Mihaela Seceleanu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
hypothyroidism, dyslipidemia, atherogenic index, coronarian risk, antimicrosomal thyroid antibodies