1. bookVolume 10 (2017): Issue 1 (April 2017)
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
access type Open Access

Electrochemical and analytical performance of boron-doped diamond electrode for determination of ascorbic acid

Published Online: 23 Jun 2017
Volume & Issue: Volume 10 (2017) - Issue 1 (April 2017)
Page range: 21 - 28
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
Abstract

The electrochemical behavior and determination of ascorbic acid (AA) was investigated at a bare boron-doped diamond (BDD) electrode using cyclic and differential pulse voltammetry. The influence of pH of supporting electrolyte and scan rate on the current response of analyte was examined to select the suitable experimental conditions. It was found that AA provided one well-shaped irreversible and diffusioncontrolled oxidation peak at +0.87 V vs. Ag/AgCl in Britton-Robinson buffer pH 4.0. Applying differential pulse voltammetry, the peak current of AA was linearly proportional to its concentration from 5 × 10-6 to 2 × 10-4 mol L-1 (R2 = 0.999), with the limit of detection of 1.1 × 10-6 mol L-1 and the good repeatability (relative standard deviation of 2.3 %). The developed electroanalytical protocol was successfully applied to determine the content of AA in commercial pharmaceutical preparations, based on the standard additions method, with the obtained recovery of 122 %. The accomplished analytical performance indicates that BDD electrodes are promising electrochemical sensors for pharmaceutical analysis.

Keywords

Bi H, Fernandes AC, Cardoso S, Freitas P (2016) Sens. Actuators B 224: 668-675.10.1016/j.snb.2015.10.072Search in Google Scholar

Cinková K, Švorc Ľ, Šatkovská P, Vojs M, Michniak P, Marton M (2016) Anal. Lett. 49: 107-121.Search in Google Scholar

Compton RG, Banks CE, Undestanding Voltammetry, 2nd Edition, Imperial College Press, London, 2010.10.1142/p726Search in Google Scholar

Ensafi AA, Taei M, Khayamian T, Arabzadeh A (2010) Sens. Actuators B 147: 213-221.10.1016/j.snb.2010.02.048Search in Google Scholar

Falkova MT, Bulatov AV, Pushina MO, Ekimov AA, Alekseeva GM, Moskvin LN (2015) Talanta 133: 82-87.10.1016/j.talanta.2014.04.092Search in Google Scholar

Fong JFY, Chin SF, Ng SM (2016) Biosens. Bioelectron. 85: 844-852.10.1016/j.bios.2016.05.087Search in Google Scholar

Guanghan L, Yu W, Leiming Y, Shuanglong H (1994) Food Chem. 51: 237-239.Search in Google Scholar

Habibi B, Jahanbakhshi M, Pournaghi-Azar MH (2011) Anal. Biochem. 411: 167-175.Search in Google Scholar

Lee C, Seo JY, Jin EH, Lim JH, Kang HY, Yang JI, Chung SJ, Yang SY, Kim JS (2016) Gastrointest. Endosc. 83: AB226.Search in Google Scholar

Mason SA, Della Gatta PA, Snow RJ, Russell AP, Wadley GD (2016) Free Radical Biol. Med. 93: 227-238.Search in Google Scholar

Muñoz RAA, Matos RC, Angnes L (2001) Talanta 55: 855-860.10.1016/S0039-9140(01)00515-XSearch in Google Scholar

Ping J, Wang Y, Wu J, Ying Y, Ji F (2012) Food Chem. 135: 362-367.Search in Google Scholar

Pisoschi AM, Pop A, Negulescu GP, Pisoschi A (2011) Molecules 16: 1349-1365.10.3390/molecules16021349625960621285920Search in Google Scholar

Silva FAS, Lopes CB, Kubota LT, Lima PR, Goulart MOF (2012) Sens. Actuators B 168: 289-296.10.1016/j.snb.2012.04.025Search in Google Scholar

Svítková J, Ignat T, Švorc Ľ, Labuda J, Barek J (2016) Crit. Rev. Anal. Chem. 46: 248-256.Search in Google Scholar

Švorc Ľ, Cinková K, Samphao A, Stanković DM, Mehmeti E, Kalcher K (2015) J. Electroanal. Chem. 744: 37-44.Search in Google Scholar

Thangamuthu R, Kumar SMS, Pillai KC (2007) Sens. Actuators B 120: 745-753.10.1016/j.snb.2006.03.048Search in Google Scholar

Tian K, Bian J, Wang B, Qi Y (2010) Electrochim. Acta 55: 3083-3088.Search in Google Scholar

Zhang X, Cao Y, Yu S, Yang F, Xi P (2013) Biosens. Bioelectron. 44: 183-190.10.1016/j.bios.2013.01.02023428731Search in Google Scholar

Zheng X, Guo Y, Zheng J, Zhou X, Li Q, Lin R (2015) Sens. Actuators B 213: 188-194.10.1016/j.snb.2015.02.044Search in Google Scholar

Zuo X, Zhang H, Li N (2012) Sens. Actuators B 161: 1074-1079.10.1016/j.snb.2011.12.013Search in Google Scholar

Zuo R, Zhou S, Zuo Y, Deng Y (2015) Food Chem. 182: 242-245.Search in Google Scholar

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