1. bookVolume 9 (2016): Issue 2 (October 2016)
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
access type Open Access

Determination of enantiomeric composition of fluoxetine by synchronous fluorescence spectrometry coupled with multivariate calibration in biological samples

Published Online: 08 Dec 2016
Volume & Issue: Volume 9 (2016) - Issue 2 (October 2016)
Page range: 163 - 168
Journal Details
License
Format
Journal
eISSN
1339-3065
First Published
10 Dec 2012
Publication timeframe
2 times per year
Languages
English
Abstract

This paper presents rapid and low cost analytical method for the determination of the fluoxetine enantiomeric composition in biological samples (urine). The combination of synchronous fluorescence spectrometry and inverse multivariate calibration methods was used. The chiral recognition of the fluoxetine was based on the creating of the diastereomeric complexes with β-cyclodextrin. A net analytical signal of diastereomeric complexes was obtained by the addition of aliquot part of urine into calibration and validation sets. This step ensures the elimination of the urine matrix effect. The synchronous fluorescence spectra at the constant wavelength differences (Δλ) of 30 and 50 nm, based on RMS %RE values, were chosen for chemometric analysis. Principal component regression (PCR) and partial least square method (PLS) were compared to determine the enantiomeric composition. The most suitable results were provided by the PLS model constructed from the synchronous data at Δλ = 50 nm. The calculated figure of merit was used for validation of proposed method.

Keywords

Ali SM, Asmat F, Maheshwari A, Koketsu M (2005) Il Farmaco 60: 445—449.10.1016/j.farmac.2005.03.003Search in Google Scholar

Asensi-Bernardi L, Martin-Biosca Y, Fornet-Herrero E, Sagrado S, Medina-Henández MJ (2013) Biomedical Chromatography 27: 377—381.Search in Google Scholar

Douša M, Lehnert P, Adamusová H, Bosáková Z (2013) Journal of Pharmaceutical and Biomedical Analysis 74: 111—116.10.1016/j.jpba.2012.10.017Search in Google Scholar

Finn MG (2002) Chirality 14: 534.10.1002/chir.10101Search in Google Scholar

Ferré J, Faber NM (2003) Chemometrics and Intelligent Laboratory Systems 69: 123—136.10.1016/S0169-7439(03)00118-7Search in Google Scholar

Gergely A (2000) Journal of Pharmaceutical and Biomedical Analysis 4: 553—561.10.1016/S1464-3456(00)80039-3Search in Google Scholar

Grodner B, Sitkiewicz D (2013) Psychiatria Polska 3: 511—516.Search in Google Scholar

Horvát P, Gergely A, Noszál B (1997) Talanta 44: 1479—1485.10.1016/S0039-9140(97)00058-1Search in Google Scholar

Konno K, Shinna I, Yui HJ (2013) Journal of Molecular Structure 1035: 260—266.10.1016/j.molstruc.2012.11.025Search in Google Scholar

Kusnir J, Leskova L (2005) Analytical letters 38: 1559—1567.10.1081/AL-200065787Search in Google Scholar

Lerena A, Dorado P, Berecz R, González A, Norberto M, De La Rubia A (2003) Journal of Chromatography B, Analytical technologies in the biomedical and life sciences 783: 25—31.10.1016/S1570-0232(02)00486-5Search in Google Scholar

Li K, Thompson M, McGregor I (2004) Journal of Chromatography B, Analytical technologies in the biomedical and life sciences 804: 319—26.10.1016/j.jchromb.2004.01.03415081926Search in Google Scholar

Mifsud J, Sqhendo LJ (2012) Journal of Pharmacy and Bioallied Sciences 4: 236—245.10.4103/0975-7406.99065Search in Google Scholar

Mohr S, Weiss JA, Spreitz J, Schmid MG (2012) Journal of Chromatography A 1269: 352—359.10.1016/j.chroma.2012.09.079Search in Google Scholar

Poláček R, Májek P (2015) International Journal of Development Research 5(8): 5240—5244.Search in Google Scholar

Poláček R, Májek P (2016) Chemické listy 110: 18—25.Search in Google Scholar

Poláček R, Májek P, Hroboňova K, Sádecka J (2016) Chirality 28: 319—324.10.1002/chir.22577Search in Google Scholar

Rajalahti T, Kvalheim OM (2011) International Journal of Pharmaceutics 417: 280—290.10.1016/j.ijpharm.2011.02.019Search in Google Scholar

Ribeiro AR, Afonso CM, Castro PML, Tiritan ME (2013) Environmental Chemistry Letters 11: 83—90.10.1007/s10311-012-0383-1Search in Google Scholar

Shamsipur M, Dastjerdi LS, Haghgoo S, Armspach D, Matt D, Aboul-Enein HY (2007) Analytica Chimica Acta 601: 130—138.10.1016/j.aca.2007.08.017Search in Google Scholar

Shen J, Yang J, Heyse W, Schweitzer H, Nagel N, Andert D, Zhu Ch, Morrison V, Nemeth GA, Chen TM, Zhao Z, Ayers T, Choi YM (2014) Journal of Pharmaceutical Analysis 4: 197—204.10.1016/j.jpha.2013.10.001Search in Google Scholar

Sullivan GR (1978) Topics in Stereochemistry 10: 2874.Search in Google Scholar

Suliman FO, Elbashir AA (2012) Journal of Molecular Structure 1019: 43—49.10.1016/j.molstruc.2012.03.055Search in Google Scholar

Wise BM, Gallagher NB, Bro R, Shaver JM, Windig W, Koch RS (2006) PLS Toolboox 4.0 for use with MatlabTM. Eigenvector Research Inc., Wenatchee.Search in Google Scholar

Wold S, Sjostrom M, Eriksson L (2001) Chemometrics and Intelligent Laboratory Systems 58: 109—130.10.1016/S0169-7439(01)00155-1Search in Google Scholar

Yee L, Wong SHY, Skrinska VA (2000) Journal of Analytical Toxicology 24: 651—655.10.1093/jat/24.7.65111043675Search in Google Scholar

Yu L, Wang S, Jiang H, Zhou H, Zeng S (2012) Journal of Chromatography A 1326: 97—104.10.1016/j.chroma.2012.03.00622436668Search in Google Scholar

Recommended articles from Trend MD

Plan your remote conference with Sciendo