Article Category: Review article
Published Online: Jun 25, 2020
Page range: 207 - 216
DOI: https://doi.org/10.1515/abm-2019-0063
Keywords
© 2019 Teerasit Techawiwattanaboon et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
Background
Leptospirosis, caused by pathogenic
Objective
To summarize current literature regarding commonly used and new promising molecular approaches to
Method
The relevant articles in
Results
Several molecular techniques have been developed for diagnosis of human leptospirosis. Polymerase chain reaction-based techniques targeting on either
Conclusion
Detection of leptospiral DNA in clinical specimens using molecular techniques enhances sensitivity for diagnosis of leptospirosis. The efficient and robust molecular detection especially in the early leptospiremic phase may prompt early and appropriate treatment leading to reduced morbidity and mortality of patients with leptospirosis.